A5101823324- Cancer-related molecular mechanisms research
- Nanoplatforms for cancer theranostics
- Extracellular vesicles in disease
- Mercury impact and mitigation studies
- Advanced Nanomaterials in Catalysis
- Plant Molecular Biology Research
- Chromosomal and Genetic Variations
- Heavy Metal Exposure and Toxicity
- Bioenergy crop production and management
- Metal-Organic Frameworks: Synthesis and Applications
- MicroRNA in disease regulation
- Agronomic Practices and Intercropping Systems
- Molecular Sensors and Ion Detection
- RNA modifications and cancer
- Conducting polymers and applications
- Oral microbiology and periodontitis research
- Trace Elements in Health
- Gold and Silver Nanoparticles Synthesis and Applications
- Electrochemical Analysis and Applications
- Advanced Image Fusion Techniques
- interferon and immune responses
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Single-cell and spatial transcriptomics
- 2D Materials and Applications
- Liver Disease Diagnosis and Treatment
Stomatology Hospital
2025
Sichuan University
2020-2025
First Hospital of China Medical University
2005-2025
Xiangtan University
2025
China Medical University
2005-2025
Zhejiang Normal University
2023-2024
Ministry of Agriculture and Rural Affairs
2024
Central South University
2023-2024
Dongguan University of Technology
2024
Huazhong University of Science and Technology
2021-2024
Conventional biomaterial-mediated osteosarcoma therapy mainly focuses on its antitumor effect yet often fails to overcome the problem of post-treatment bone tissue defect repair. Simultaneously, minimally invasive drug delivery methods are becoming spotlights for normal preservation. Herein, an injectable curcumin-microsphere/IR820 coloaded hybrid methylcellulose hydrogel (Cur-MP/IR820 gel) platform was designed and regeneration. In vitro, K7M2wt cells were eradicated by hyperthermia...
Abstract Populus euphratica is well adapted to extreme desert environments and an important model species for elucidating the mechanisms of abiotic stress resistance in trees. The current assembly P. genome highly fragmented with many gaps errors, thereby impeding downstream applications. Here, we report improved chromosome‐level reference (v2.0) using single‐molecule sequencing chromosome conformation capture (Hi‐C) technologies. Relative previous genome, our represents a nearly 60‐fold...
Radiations are especially important for generating species biodiversity in mountainous ecosystems. The contribution of hybridization to such radiations has rarely been examined. Here, we use extensive genomic data test whether was involved evolutionary radiation within Rhododendron subgenus Hymenanthes, whose members show strong geographic isolation the mountains southwest China. We sequenced genomes 143 this and 93 four other subgenera, found that Hymenanthes monophyletic radiated during...
Abstract Gold nanorods (GNRs) are a unique class of metal nanostructures that have attractive potentials in biomedical applications, and the concern on their biological safety is concomitantly increasing. Hemocompatibility extremely important as contact with blood circulation unavoidable during vivo delivery. Herein, two kinds GNRs coated hexadecyltrimethylammonium bromide (C‐GNRs) or poly(sodium‐ p ‐styrenesulfonate) used to test potential toxicological effects blood. C‐GNRs positive...
Abstract Dioecy, the presence of separate sexes on distinct individuals, has evolved repeatedly in multiple plant lineages. However, specific mechanisms by which sex systems evolve and their commonalities among species remain poorly understood. With both XY ZW systems, family Salicaceae provides a system to uncover evolutionary forces driving chromosome turnovers. In this study, we performed genome-wide association study characterize determination two Populus species, P. euphratica alba. Our...
Osteosarcoma (OS) is the most serious bone malignancy, and survival rate has not significantly improved in past 40 years. Thus, it urgent to develop a new strategy for OS treatment. Chemodynamic therapy (CDT) as novel therapeutic method can destroy cancer cells by converting endogenous hydrogen peroxide (H2 O2 ) into highly toxic hydroxyl radicals (·OH). However, efficacy of CDT severely limited low catalytic efficiency overexpressed glutathione (GSH). Herein, an excellent nanocatalytic...
Aflatoxins (AFTs), as a group 1 carcinogen, could lead to hepatocellular carcinoma (HCC). Dietary intake is the primary way of AFT exposure in humans. However, contribution foodborne HCC burden remains unknown recent years China. Hence, present study was conducted estimate attributed by using disability-adjusted life (DALYs). The risk assessment used incidence related exposure. Concentrations AFTs peanuts, peanut oil, corn, and corn products were retrieved from literature published between...
Nonalcoholic fatty liver disease (NAFLD) can progress to cirrhosis and cancer if left untreated. Therefore, it is of great importance develop useful tools for the noninvasive accurate diagnosis NAFLD. Increased microenvironmental viscosity was considered as a biomarker NAFLD, but occurrence increased in other diseases highly reduces accuracy NAFLD by single detection viscosity. Hence, very necessary seek second It has been innovatively proposed that overexpressed heme oxygenase-1 enzyme...
Transforming growth factor-beta (TGF-β) signaling is essential in initialization and progression of hepatocellular carcinoma (HCC). Therefore, a treatment targeting TGF-β pathway may be promising option for HCC control.First, publicly available RNA-seq datasets clinical characteristics 374 patients The Cancer Genome Atlas (TCGA) database were downloaded. Then, Cox regression analysis LASSO used to construct prognostic model family genes. area under the curve (AUC) risk signature was...
Abstract Background Salicaceae species have diverse sex determination systems and frequent chromosome turnovers. However, compared with poplars, the diversity of in willows is poorly understood, little known about evolutionary forces driving their turnover. Here, we characterized two Salix species, S. chaenomeloides arbutifolia , which an XY system on 7 15, respectively. Results Based assemblies regions, found that mechanism may underlying similarities both involving intact and/or partial...
Abstract Populus species have long been used as model organisms to study the adaptability of trees and evolution sex chromosomes. As a belonging section limited tropical areas, P. qiongdaoensis genome contains important information for poplar studies protection. Here, we report chromosome‐level assembly annotation female . Gene family clustering, positive selection detection historical reconstruction population dynamics revealed adaptation , showed convergent with another poplar, ilicifolia...
Perovskite solar cells have experienced rapid development in the last few years due to their excellent photovoltaic properties, and efficiency stability attracted widespread attention. Passivating interfacial defects has been universally recognized as an effective performance enhancement strategy for perovskite (PSCs), but most reported strategies often fail simultaneously meet requirements of stability. This paper proposes enhance passivation function phosphine oxide by fluorination. On one...
<title>Abstract</title> Allopolyploidy involves the fusion of genomes from different lineages through hybridization and chromosome doubling. However, detecting early allopolyploidy events in evolutionary history understanding specific subgenomic evolution that contributes to origin adaptive innovations for species radiation can be challenging. Here, we sequenced representing all three subfamilies Salicaceae, a woody model clade, collected epigenetic transcriptomic samples. We revealed one...