Abstract Acoustic sensors with ultrahigh sensitivity, broadband response, and high resolution are essential for high-precision nondestructive weak signal detection technology. In this paper, based on the size effect of an ultrahigh-quality ( Q ) calcium fluoride (CaF 2 resonator, a acoustic is detected by dispersive response regime in which acoustic, elastic wave modulates geometry converted to resonance frequency shift. Through structural design sensitivity reaches 11.54 V/Pa at 10 kHz...

SARS-CoV-2 continues to pose a threat public health. Main protease (Mpro) is one of the most lucrative drug targets for developing specific antivirals against infection. By targeting Mpro, peptidomimetic nirmatrelvir able inhibit viral replication and reduce risk progression severe COVID-19. However, multiple mutations in gene encoding Mpro emerging variants raise concern resistance. In present study, we expressed 16 previously reported mutants (G15S, T25I, T45I, S46F, S46P, D48N, M49I,...

Chirp modulation can generate a relatively flat electro-optic frequency comb (EO comb) and offers the advantage of reconfigurability, demonstrating significant potential in high-precision sensing absorption spectroscopy measurements. However, nonresonant devices such as waveguides are susceptible to limitations efficiency bandwidth during modulation. In this paper, by utilizing chirp resonance mode, we have realized an EO based on lithium niobate resonator with small tooth spacing high...

The optical resonators with ultrahigh quality (Q) factor are advantageous as highly sensitive sensors, benefiting from the sharp characteristics of their resonance peaks. However, this high sensitivity is usually achieved at expense linear range, so sensing dynamic range physically limited. In paper, we propose a nonlinear modulation method based on generation an interference phenomenon between two scattering amplitudes. recursive property Bessel function utilized to construct expressions...

Optical whispering-gallery mode (WGM) sensors have been developed for the detection of clinically relevant biomolecules, materials in different phases and forms, field-based sensing applications. The optical resonance inside a microsphere cavity, induced by total internal reflection that excites WGM, small refractive index change caused loading nano-scale particles, results detectable shift resonant dip. We confirmed this volume-dependent reactive mechanism using SiO2 nanoparticles obtained...

We propose a low-frequency magnetic sensing method using magnetically modulated microcavity resonant mode. Our sensitive unit with periodically changing poles is formed by combining an AC excitation coil microcavity. The vibrates at the frequency of amplitude-modulated signal and changes its mode when interacts field. Signal processing performed on spectrum to obtain signals. results experiment show that measured sensitivity 0.5 Hz field 12.49 V/mT, bias instability noise 16.71 nT achieved....

The parity-time (PT) -symmetric gyroscope system is able to solve the problem of achieving high sensitivity in a reduced footprint for optical gyroscopes by manipulating physical properties exceptional points (EP). Nevertheless, its tuning intricate and hard read, which hinders practical implementation. On contrary, real frequency splitting simple anti-parity-time(APT)-symmetric represents viable alternative conventional PT-symmetric gyroscope. However, due fabrication process required...

Abstract The resonant amplification of the optical and mechanical components in cavity optomechanical systems enhances performance sensing applications, which rely on precise frequency control narrowed linewidth. This study proposes a direct closed‐loop feedback technique for narrow linewidth phonon laser based self‐oscillation. By continuously pumping resonator with laser, is achieved an oscillation 17.58 MHz, exhibiting just 0.44 mHz effective Q 4 × 10 , while preserving linear response....

In non-Hermitian systems, enhancing sensitivity under exceptional point (EP) conditions offers an ideal solution for reconciling the trade-off between and size constraints in sensing applications. However, practical application is limited by undesired to external fluctuations, noise, errors signal amplification synchronization. This paper presents a precisely controlled EP tracking detection system (EPTDS) that achieves long-term rapid locking near constructing second-order optical unit,...

Acceleration measurement is widely used in military, civil, and industrial applications. However, it difficult for traditional microelectromechanical systems (MEMS) accelerometers to combine high sensitivity large bandwidth. Therefore, we propose a Fabry-Perot (F-P) optomechanical accelerometer based on suspended Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> membrane resonator. We...

Changes in coagulation indexes, thromboelastogram(TEG) and autoantibodies patients with recurrent pregnancy loss (RPL) different number of abortions were analyzed.Medical records 48 abortion, treated Quzhou people's Hospital from November 2019 to October 2020, collected as the observation group. Based on abortions, divided into Group-A (Two n=21), Group-B (Three n=16) group C (Abortion ≥ four times, n=11). Records 50 healthy pregnant women our hospital same period selected control...

Whispering gallery mode (WGM) crystalline resonator is an excellent platform for acoustic sensing because the quality ( <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Q</i> ) factor of 10 <sup xmlns:xlink="http://www.w3.org/1999/xlink">11</sup> can theoretically increase sensitivity by more than three orders magnitude. However, ultrahigh and wide dynamic response range cannot be achieved simultaneously, due to extremely narrow linewidth...

The bound states in the continuum (BIC) support anomalous resonances optical or terahertz band with a theoretically infinite quality factor. Therefore, it has great application prospects field of sensors. However, current regulation BIC mainly relies on asymmetry material structure, which requires high processing technology. structure can hardly be effectively adjusted once is formed. In this work, we propose new metasurface consisting an array rectangular hole combined aluminum and...

This paper aims to investigate the nonreciprocity caused by orthogonal magnetic field (OMF) vertical light direction propagating in a polarization-maintaining fiber-optic gyro (PM-FOG). In field, nonreciprocal phase error (NPE) results from small change of propagation constants two opposite waves fiber coil. Even using PM coil, pressure, twist, and other imperfections will polarization state, which may lead an instable drift PM-FOGs. phenomenon was observed 0°-coupling regime is commonly...

In this paper, a simple sensing method based on silicon oxide microcavity optomechanical oscillator (OMO) is proposed and demonstrated for the detection of acoustic signals. Firstly, resonance damping was reduced by improving optical quality factor ( Q o ) increasing sphere-to-neck ratio. After optimizing process, microsphere OMO fabricated, which has an ultra-high mechanical (6.8 × 10 6 greater ratio (∼11:1), ultra-narrow linewidth phonon laser (∼1 Hz) constructed. Secondly, changing...

Abstract The design and fabrication processes of the stimulated Brillouin laser (SBL) are complex, it is affected by many factors such as temperature resonance shift. In this study, we have fabricated a using fiber ring resonator with Q factor = 7.1 × 10 8 depth ( h ) 96%. free spectral range automatic feedback control technology proposed to realize accurate matching resonant mode Stokes mode. influence on SBL frequency shift suppressed. fluctuation SBL’s decreases 5 times. maximum steady...