Siming Li

ORCID: 0000-0001-9498-9689
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About
Contact & Profiles
Research Areas
  • Traditional Chinese Medicine Analysis
  • Eosinophilic Disorders and Syndromes
  • Traditional Chinese Medicine Studies
  • Sarcoidosis and Beryllium Toxicity Research
  • Cutaneous Melanoma Detection and Management
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Computational Drug Discovery Methods
  • Cancer-related molecular mechanisms research
  • Adipose Tissue and Metabolism
  • Autism Spectrum Disorder Research
  • Cancer, Hypoxia, and Metabolism
  • Melanoma and MAPK Pathways
  • Catalytic Processes in Materials Science
  • Chalcogenide Semiconductor Thin Films
  • Liver Disease Diagnosis and Treatment
  • Phagocytosis and Immune Regulation
  • Inflammasome and immune disorders
  • Cardiovascular Health and Risk Factors
  • Protein Tyrosine Phosphatases
  • Atherosclerosis and Cardiovascular Diseases
  • interferon and immune responses
  • Immune cells in cancer
  • Lipid metabolism and biosynthesis

Capital Medical University
2023-2025

University of Michigan
2014-2025

Centre for Movement Disorders
2023

Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2021

Xiyuan Hospital
2013-2021

Beijing University of Chinese Medicine
2013-2018

Tianjin University
2016

Jilin University
2015

Pyroptosis is a new programmed cell death discovered in recent years. plays an important role various diseases. Nevertheless, there are few bibliometric analysis systematically studies this field. We aimed to visualize the research hotspots and trends of pyroptosis using help understand future development basic clinical research.The articles reviews regarding were culled from Web Science Core Collection. Countries, institutions, authors, references keywords field visually analyzed by...

10.3389/fimmu.2021.731933 article EN cc-by Frontiers in Immunology 2021-08-18

Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by injury to steatotic hepatocytes that triggers the release of endogenous danger-associated molecular patterns. Recent work demonstrated exposed lipid droplets (LDs) serve as a pathogenic signal promotes monocyte infiltration and its maturation into triggering receptor expressed in myeloid cells 2 (TREM2+) macrophages MASH liver. Here we explore role LD exposure modulating inflammatory signaling macrophages. We found...

10.1016/j.celrep.2025.115310 article EN cc-by-nc-nd Cell Reports 2025-02-01

Insulin-like growth factor binding protein 6 (IGFBP6) is a key in regulating the effects of insulin-like 2 (IGF2) on animal and development, but mechanism far from known. In this study, 5'-terminal sequence IGFBP6 gene (from −920 to −1 bp) which may regulate expression was sequenced Bama mini-pigs, Tibetan Landrace pigs, Large White pigs Northeast wild boars screen for single nucleotide polymorphisms (SNPs) analyze relations with body size traits swine through chi-square test analysis. The...

10.1080/19768354.2015.1108227 article EN Animal Cells and Systems 2015-11-02

Menopausal women appear lipid metabolism disorder with the ovarian function decline and estrogen levels decreased. Modern clinical usually use replacement therapy long time application lots of side effect appear. Traditional Chinese medicine has more secure effective methords,using warming Yang drugs methods. And previous study proves Astragali Complanati Semen water extraction a good role in regulation blood lipids. Because liver is most important organ on regulating metabolism, therefore...

10.19540/j.cnki.cjcmm.20180408.002 article EN PubMed 2018-06-01

<div>Abstract<p><b>Purpose:</b> Ethnic differences are conspicuous in melanoma. This study is to obtain a comprehensive view of genomic landscape and better understanding the correlations gene mutation status with clinicopathologic characteristics disease prognosis Asian population.</p><p><b>Experimental Design:</b> A total 2,793 melanoma patient samples were retrospectively collected analyzed for mutations C-KIT, BRAF, NRAS, PDGFRA coding...

10.1158/1078-0432.c.6525039 preprint EN 2023-03-31

<div>Abstract<p><b>Purpose:</b> Ethnic differences are conspicuous in melanoma. This study is to obtain a comprehensive view of genomic landscape and better understanding the correlations gene mutation status with clinicopathologic characteristics disease prognosis Asian population.</p><p><b>Experimental Design:</b> A total 2,793 melanoma patient samples were retrospectively collected analyzed for mutations C-KIT, BRAF, NRAS, PDGFRA coding...

10.1158/1078-0432.c.6525039.v1 preprint EN 2023-03-31

Recent progress has been made in improving efficiency Cu(In,Ga)Se2 (CIGS) absorbers with steady increases peak efficiency. One way this achieved is by adding Ag to CIGS (ACIGS) achieve higher VOC. However, these efficiencies are still well below the Shockley-Queisser limit, and traps acting as recombination centers compensating one thing limiting solar Past research shown that alkali treatment can improve metastability problems CIGS, but less understood about role of treatments ACIGS. Here,...

10.2172/1807858 article EN 2020-06-25
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