A5014037341- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Renal cell carcinoma treatment
- Cancer Genomics and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Prostate Cancer Diagnosis and Treatment
- Renal and Vascular Pathologies
- Urological Disorders and Treatments
- Prostate Cancer Treatment and Research
- Epigenetics and DNA Methylation
- Eosinophilic Disorders and Syndromes
- Sexual function and dysfunction studies
- Gastrointestinal motility and disorders
- Microscopic Colitis
- Myasthenia Gravis and Thymoma
- Genetic factors in colorectal cancer
- Medical Imaging and Pathology Studies
- Pediatric Urology and Nephrology Studies
- Renal and related cancers
- Clostridium difficile and Clostridium perfringens research
- Organ Donation and Transplantation
- Urologic and reproductive health conditions
- Esophageal Cancer Research and Treatment
- Cardiac tumors and thrombi
- Eosinophilic Esophagitis
Iwate Medical University
2018-2024
Iwate Prefectural Central Hospital
2022
Toyota Industries (Japan)
2019
The aim of this study was to evaluate the clinical validity monitoring urine pellet DNA (upDNA) bladder cancer (BC) by digital PCR (dPCR) as a biomarker for early recurrence prediction, treatment efficacy evaluation, and no-recurrence corroboration. Tumor panel sequencing first performed select patient-unique somatic mutations monitor both upDNA circulating tumor (ctDNA) dPCR. For longitudinal using well plasma ctDNA, an average 7.2 (range, 2 12) time points per case were with dPCR assay 32...
Abstract Biomarkers that could detect the postoperative recurrence of upper tract urothelial carcinoma (UTUC) have not been established. In this prospective study, we aim to evaluate utility individualized circulating tumor DNA (ctDNA) monitoring using digital PCR (dPCR) as a biomarker for UTUC in perioperative period. Twenty‐three patients who underwent radical nephroureterectomy (RNU) were included. each patient, whole exome sequencing by next‐generation and TERT promoter carried out....
Introduction Decreased renal function after radical nephroureterectomy is one of the most important complications because it contributes to decision initiate adjuvant chemotherapy. This study aimed investigate clinical factors associated with changes in elderly patients. Methodology A total 145 patients who underwent for upper tract urothelial carcinoma were evaluated. The was calculated preoperatively, postoperatively, and month long-term change investigated once a year. association between...
Treatment options as second-line therapy for advanced ureteral carcinoma are limited and patients experiencing recurrence after first-line cisplatin-based chemotherapy have a poor prognosis. Recently, the PD-1 inhibitor pembrolizumab provided better survival benefit with complete response rate (9.2%) chemoresistatant urothelial carcinoma. However, dynamic change of cancer microenvironment about cases still unknown. We herein report case 57-year-old man who had been diagnosed localized,...
Prostate cancer in the anterior region may be missed on transrectal systematic biopsy (SBx). Therefore, this study aimed to evaluate performance of magnetic resonance imaging-transrectal ultrasound (MRI-TRUS) fusion targeted (TBx) detecting patients with a history SBxs. biopsies were performed 224 after multiparametric MRI, among whom 119 prostate imaging reporting and data system (PI-RADS version 2) scores 3 5 underwent MRI-TRUS TBxs. Afterward, detection rates (CDRs) TBx-positive core...
You have accessJournal of UrologyBladder Cancer: Upper Tract Transitional Cell Carcinoma II (MP38)1 May 2024MP38-04 PREDICTION OF RECURRENCE USING CASE-SPECIFIC CIRCULATING TUMOR DNA IN POSTOPERATIVE PATIENTS WITH UPPER TRACT UROTHELIAL CARCINOMA Daichi Tamura, Masakazu Abe, Daiki Ikarashi, Renpei Kato, Shigekatsu Maekawa, Yutaka Suzuki, Hidewaki Nakagawa, and Wataru Obara TamuraDaichi Tamura , AbeMasakazu Abe IkarashiDaiki Ikarashi KatoRenpei Kato MaekawaShigekatsu Maekawa SuzukiYutaka...
Introduction Secondary eosinophilia due to solid tumors is a rare case. This the first study report secondary renal cancer in patient on dialysis. Case presentation A 70‐year‐old man, long‐term hemodialysis was incidentally detected with right cancer, and workup performed revealed eosinophilia. Allergic symptoms caused by were initially considered; however, treatment did not lead any improvement Therefore, nephrectomy for performed. The resolution of after surgery suggested as cause...
Robotic surgery has become widely used in the field of urology. We experienced concurrent robot-assisted radical prostatectomy (RARP) and partial nephrectomy (RAPN) for complex cases synchronous primary cancers. Concurrent RARP RAPN with horseshoe kidney have not been reported to date. Mean operative time was 398.6 minutes mean total console 259.6 minutes. Total estimated blood loss 313.4 mL. None patients required conversion open surgery, none needed transfusion, no perioperative...
Background: The long-term split renal function after robot-assisted partial nephrectomy (RAPN) is yet to be elucidated. This study aimed assess of RAPN, using scintigraphy, and identify clinical factors related deterioration on the affected side kidney. Patients Methods: RAPN for small tumors was performed, evaluated 99m-Tc DTPA scintigraphy before 1 year surgery. Clinical (age, gender, body mass index, tumor side, presence urinary protein, diabetes, hypertension, dyslipidemia),...
Objective: Old age is a risk factor for Clostridioides difficile infection (CDI). As the world's aging population increases, identifying factors CDI in elderly patients matter of urgency. This study examined relationship between relapse and nutritional status using geriatric index (GNRI). Patients Methods: Between January 2016 December 2021, 108 were diagnosed with CDI. Of patients, 19 excluded because younger (<65 years), early death within 14 days initial diagnosis, insufficient data. The...
You have accessJournal of UrologyCME1 Apr 2023PD46-01 DETECTION OF INDIVIDUALIZED MUTATIONS AND MONITORING POSTOPERATIVE RECURRENCE USING CIRCULATING TUMOR DNA IN PATIENTS WITH UPPER TRACT UROTHELIAL CARCINOMA Daichi Tamura, Masakazu Abe, Daiki Ikarashi, Renpei Kato, Yoichiro Shigekatsu Maekawa, Mitsugu Kanehira, Ryo Takata, Yutaka Suzuki, Hidewaki Nakagawa, Satoshi Nishizuka, and Wataru Obara TamuraDaichi Tamura More articles by this author , AbeMasakazu Abe IkarashiDaiki Ikarashi...
Abstract Introduction: Approximately half of high-risk non-muscle-invasive bladder cancers (NMIBCs) recur after transurethral resection the tumor (TURBT), whereas conventional urological testing for cancer (BC) patients has been considered invasive and with low sensitivity. Our previous reports have shown that circulating DNA (ctDNA) monitored by digital PCR (dPCR) can predict relapse evaluate treatment efficacy in digestive tract cancers. In BC patients, tumor-derived genetic mutations...
Abstract Although the role of laparoscopic nephrectomy (LN) has been established, few studies have reported cases LN in individuals with scoliosis. Here we report a case right patient severe convex A 26‐year‐old man presented fever. His medical history comprised lumbar CT revealed hydronephrosis and kidney stones. Pyelonephritis requiring was diagnosed. Right feasible elaborate perioperative care. The postoperative course uneventful no relapse urinary tract infection.
Recent studies suggest that window glare is affected by more parameters than the four main variables.The view through a one of which includes both environmental and humanistic factors.Two series subjective experiments were conducted using scale-model with an artificial window.The first experiment showed higher contrast within resulted in discomfort evaluation, when average luminance was same.The moderate frequency dark-light bands evaluation uniform luminance.The second horizontal division...
You have accessJournal of UrologyCME1 May 2022PD58-03 DETECTION OF INDIVIDUALIZED MUTATION USING PLASMA AND URINARY CIRCULATING TUMOR DNA IN PATIENTS WITH UPPER TRACT UROTHELIAL CARCINOMA Daichi Tamura, Masakazu Abe, Renpei Kato, Yoichiro Shigekatsu Maekawa, Mitsugu Kanehira, Ryo Takata, Yutaka Suzuki, Hidewaki Nakagawa, Satoshi Nishizuka, and Wataru Obara TamuraDaichi Tamura More articles by this author , AbeMasakazu Abe KatoRenpei Kato KatoYoichiro MaekawaShigekatsu Maekawa KanehiraMitsugu...
A 75-year-old male visited a clinic with the chief complaint of pollakiuria. computed tomography scan revealed, left adrenal mass, and patient was then referred to our hospital. Since malignant tumor could not be ruled out. We performed laparoscopic resection. Postoperative histopathological findings revealed mass bronchogenic cyst, which had no continuity normal gland. The postoperative course uneventful, recurrence has been observed. Retroperitoneal cysts are rare often difficult diagnose...
You have accessJournal of UrologyBladder Cancer: Upper Tract Transitional Cell Carcinoma I (PD43)1 Sep 2021PD43-03 INDIVIDUALIZED MUTATION DETECTION IN PLASMA AND URINARY CIRCULATING TUMOR DNA FOR MONITORING UPPER TRACT UROTHELIAL CARCINOMA USING DIGITAL POLYMERASE CHAIN REACTION Daichi Tamura, Masakazu Abe, Renpei Kato, Yoichiro Shigekatsu Maekawa, Mitsugu Kanehira, Ryo Takata, Satoshi Nishizuka, Hidewaki Nakagawa, and Wataru Obara TamuraDaichi Tamura More articles by this author ,...
Objective To investigate if the use of therapeutic agents for dysuria is a risk factor primary recurrence non-muscle invasive bladder cancer (NMIBC). Methods First, patients with NMIBC were divided into two groups: non-recurrence group and group. Patient characteristics compared between both groups. The factors that statistically different groups identified by multivariate analysis. Second, we non-risk groups, differences in recurrence-free survival (RFS) analyzed before after propensity...