A5036591343- Asthma and respiratory diseases
- Pediatric health and respiratory diseases
- COVID-19 and Mental Health
- Stress and Burnout Research
- Tryptophan and brain disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Stress Responses and Cortisol
- Inflammasome and immune disorders
- Allergic Rhinitis and Sensitization
- Long-Term Effects of COVID-19
- Dermatology and Skin Diseases
Instituto Politécnico Nacional
2014-2024
Allergic rhinitis (AR) has considerable impact on the general health of individuals. Therefore, treatment trials should include an evaluation quality life. We aimed to determine changes in life moderate/severe AR patients treated with standard addition dialyzable leukocyte extract (DLE), a peptide-based immunomodulator. In prospective, non-controlled trial, DLE was added regimen for AR. administered orally at 2 mg per day 5 days, followed by 4 week weeks, and then weeks. The primary...
Major depressive disorder (MDD) is a mood that has become global health emergency according to the World Health Organization (WHO). It affects 280 million people worldwide and leading cause of disability financial loss. Patients with MDD present immunoendocrine alterations like cortisol resistance inflammation, which are associated in neurotransmitter metabolism. There currently numerous therapeutic options for patients MDD; however, some studies suggest high rate failure. multiple...
Background: Dialyzable leukocyte extracts (DLE) are heterogeneous mixtures of peptides less than 10 kDa in size that used as immunomodulatory adjuvants immune-mediated diseases. TransferonTM is DLE manufactured by National Polytechnic Institute (IPN), and registered Mexican health-regulatory authorities an drug commercialized nationally. The proposed mechanism action induction a Th1 immunoregulatory response. Despite it widely used, to date there no reports adverse events related the...
This article was originally published online on 03 February 2014 Dialyzable leukocyte extracts (DLE) are human blood derived peptides less than 12kDa in size. DLE hypothesized to induce a TH1 response, which makes them useful the treatment of allergic disease. The purpose this study determine changes symptomatology patients with moderate and severe rhinitis treated standard plus DLE. We analyzed clinical files 68 receiving dialyzable as adjuvant for period between 2009 2013, at our...