Nektarios Koufopoulos

ORCID: 0000-0001-9502-7916
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About
Contact & Profiles
Research Areas
  • Cancer and Skin Lesions
  • Breast Lesions and Carcinomas
  • Ovarian cancer diagnosis and treatment
  • Sarcoma Diagnosis and Treatment
  • Metastasis and carcinoma case studies
  • Endometrial and Cervical Cancer Treatments
  • Breast Cancer Treatment Studies
  • Cancer Diagnosis and Treatment
  • AI in cancer detection
  • Cardiac tumors and thrombi
  • Salivary Gland Tumors Diagnosis and Treatment
  • Reproductive Biology and Fertility
  • Radiomics and Machine Learning in Medical Imaging
  • Lymphoma Diagnosis and Treatment
  • Uterine Myomas and Treatments
  • Adrenal and Paraganglionic Tumors
  • Cancer Immunotherapy and Biomarkers
  • Head and Neck Surgical Oncology
  • Soft tissue tumor case studies
  • Renal cell carcinoma treatment
  • Urologic and reproductive health conditions
  • Cutaneous lymphoproliferative disorders research
  • Vascular Tumors and Angiosarcomas
  • Cancer Treatment and Pharmacology
  • Cancer Risks and Factors

National and Kapodistrian University of Athens
2011-2025

General Hospital of Athens Elpis
2022-2025

Athens Medical Center
2022-2025

LETO Maternity Hospital
2022-2025

University of Crete
2025

Hippocration General Hospital
2024

University General Hospital Attikon
2019-2023

University of Ioannina
2023

Istanbul Medipol University
2023

401 General Military Hospital of Athens
2022

Background: Basic research using animal models is essential for investigating pathogenic molecular mechanisms and exploring new pharmaceutical treatments tumors, including breast tumors. Methods results: Thirty-six female Wistar rats, four weeks old, were included in the study, but six excluded early due to health complications, leaving 30 rats final cohort. Mammary gland tumors induced a single subcutaneous dose of 20 mg 7,12-dimethylbenz(a)anthracene (DMBA) on right side MCF7 cells...

10.7759/cureus.77648 article EN Cureus 2025-01-19

Hybrid Peripheral Nerve Sheath Tumors (HPNSTs) are rare benign neoplasms that exhibit a combination of histological features from multiple types peripheral nerve sheath tumors, including schwannomas, neurofibromas, and perineuriomas. These tumors present diagnostic challenge due to their morphological variability. In this article, we aim summarize the key morphological, histological, molecular characteristics HPNSTs, providing insights into approaches. We review different hybrid subtypes,...

10.3390/diagnostics15070855 article EN cc-by Diagnostics 2025-03-27

Mucinous cystadenocarcinoma is an extremely rare variant of primary breast tumor which histologically similar to mucinous the ovary and pancreas. Herein we report a case 63 years old woman diagnosed with diverse histological types non-synchronous tumors, medullary carcinoma right left breast. Macroscopically neoplasm appeared multilocular filled mucoid material. Under light microscopy cystic areas were lined by columnar cells abundant intracellular extracellular mucin. Solid composed tall...

10.4081/rt.2017.7016 article EN cc-by-nc Rare Tumors 2017-10-01

Advanced Raman spectroscopy (RS) systems have gained new interest in the field of medicine as an emerging tool for vivo tissue discrimination. The coupling RS with artificial intelligence (AI) algorithms has given a boost to analyze spectral data real time high specificity and sensitivity. However, limitations are still encountered due large amount clinical which required pre-training process AI algorithms. In this study, human healthy cancerous colon specimens were surgically resected from...

10.3390/opt4020022 article EN cc-by Optics 2023-04-27

Objective. This study investigates the potential of an artificial intelligence (AI) methodology, radial basis function (RBF) neural network (ANN), in evaluation thyroid lesions. Study Design. The was performed on 447 patients who had both cytological and histological agreement. Cytological specimens were prepared using liquid-based cytology, result based subsequent surgical samples. Each specimen digitized; these images, nuclear morphology features measured by use image analysis system....

10.1155/2020/5464787 article EN cc-by Journal of Thyroid Research 2020-11-24

Myeloproliferative neoplasms (MPNs) are subdivided into Philadelphia (Ph) chromosome-positive chronic myeloid leukemia (CML) and Ph-negative MPNs. BCR::ABL1 translocation is essential for the development diagnosis of CML; on other hand, majority MPNs characterized by generally mutually exclusive mutations Janus kinase 2 ( JAK2 ), calreticulin CALR or thrombopoietin receptor/myeloproliferative MPL ). have been described essentially in wild-type thrombocythemia primary myelofibrosis. Rarely...

10.3389/fcell.2024.1391078 article EN cc-by Frontiers in Cell and Developmental Biology 2024-03-26

Lymphoepithelial or lymphoepithelioma-like carcinoma is a poorly differentiated located outside the nasopharynx with similar morphologic characteristics to its nasopharyngeal counterpart. of lung rare subtype squamous cell frequently associated Epstein-Barr virus (EBV) infection, accounting for approximately 1% non-small carcinomas (NSCLC). We herewith present case 78-year-old female patient who was diagnosed lymphoepithelial lung, emphasizing distinct epidemiological features, clinical...

10.7759/cureus.70309 article EN Cureus 2024-09-27
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