Leandro A. Vieira

ORCID: 0000-0001-9512-2999
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About
Contact & Profiles
Research Areas
  • Pesticide Exposure and Toxicity
  • Insect and Pesticide Research
  • Cholinesterase and Neurodegenerative Diseases
  • Computational Drug Discovery Methods
  • Free Radicals and Antioxidants
  • Antioxidant Activity and Oxidative Stress
  • Phytochemistry Medicinal Plant Applications
  • vaccines and immunoinformatics approaches
  • SARS-CoV-2 and COVID-19 Research
  • Phytochemicals and Antioxidant Activities

Military Institute of Engineering
2021-2025

Açaí, Euterpe oleracea Mart., is a native plant from the Amazonian and rich in several phytochemicals with anti-tumor activities. The aim was to analyze effects of açaí seed oil on colorectal adenocarcinoma (ADC) cells. In vitro analyses were performed CACO-2, HCT-116, HT-29 cell lines. strains treated for 24, 48, 72 h, viability, death, morphology analyzed. Molecular docking evaluate interaction between major compounds Annexin A2. viability assay showed cytotoxic effect Acai induced...

10.3390/metabo13070789 article EN cc-by Metabolites 2023-06-25

The acute respiratory syndrome caused by the SARS-CoV-2, known as COVID-19, has been ruthlessly tormenting world population for more than six months. However, so far no effective drug or vaccine against this plague have emerged yet, despite huge effort in course researchers and pharmaceutical companies worldwide. Willing to contribute with fight defeat we performed a virtual screening study on library containing Food Drug Administration (FDA) approved drugs, search molecules capable of...

10.1080/07391102.2020.1869096 article EN Journal of Biomolecular Structure and Dynamics 2021-01-08
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