- Cervical Cancer and HPV Research
- Research on Leishmaniasis Studies
- Phytochemistry Medicinal Plant Applications
- Science and Education Research
- Women's cancer prevention and management
- T-cell and Retrovirus Studies
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Bee Products Chemical Analysis
- Agricultural and Food Sciences
- Trypanosoma species research and implications
- Microbial Natural Products and Biosynthesis
- Fungal Biology and Applications
- Mosquito-borne diseases and control
- Plant Pathogens and Fungal Diseases
- Antioxidant Activity and Oxidative Stress
- Coconut Research and Applications
- Indigenous Health and Education
- Tannin, Tannase and Anticancer Activities
- Fungal Infections and Studies
- Childhood Cancer Survivors' Quality of Life
- Allergic Rhinitis and Sensitization
- Palliative and Oncologic Care
- Enzyme Production and Characterization
- Indoor Air Quality and Microbial Exposure
Universidade Federal do Maranhão
2016-2025
Anticancer Fund
2024
Universidade Federal de São Paulo
2024
Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão
2024
Total (France)
2024
Centro de Excelência em Bioinformática
2023
Weatherford College
2023
Universidade Estadual de Campinas (UNICAMP)
2023
Military Institute of Engineering
2023
University of Hradec Králové
2023
To investigate the association between pacifier use and bottle-feeding unfavorable behaviors during breastfeeding. A cross-sectional study was conducted with 427 babies/mothers. Socio-demographic, perinatal data, information about of artificial nipples (pacifier and/or bottle) were collected through a questionnaire. The breastfeeding aspects regarding position, affectivity, sucking behavior, baby responses, breast anatomy evaluated observation chi-squared test multiple linear regression...
Human papillomavirus (HPV) is a member of the Papillomaviridae family. The prevalence HPV genotypes may vary according to region and population studied. Quilombo communities are ethnic racial groups with difficult access health services compared general in Brazil. aim this study was identify specific types correlating sociodemographic/behavioral characteristics cervical smear cytological abnormalities Quilombola women. This cross-sectional included 395 women users Unified Health System...
Introduction: Metabolic syndrome (MS) is a group of cardiovascular risk factors associated with insulin resistance and driven by underlying factors, including visceral obesity, systemic inflammation, cellular dysfunction. The prevalence this condition among children adolescents has increased considerably in the last four decades. Thus, use noninvasive diagnostic techniques may allow early interventions population, preventing development or metabolic impairments adulthood. Objective: To...
Abstract Acetylcholinesterase (AChE; EC 3.1.1.7) inhibition in vitro is an effective method for monitoring pesticide contamination, particularly organophosphates, offering advantages over vivo approaches. Environmental factors like temperature, age, and stress can alter enzyme activity vivo, making controlled studies necessary. This research focused on the brain AChE of Nile tilapia (Oreochromis niloticus), a key species global aquaculture, to detect organophosphate contamination. The study...
O objetivo do estudo foi analisar o rastreamento câncer colo útero no Maranhão, através dos dados Sistema de Informação Câncer Colo Útero (Siscolo). Foi realizado um descritivo retrospectivo, com secundários 139.505 exames citopatológicos registrados Siscolo ano 2011. As variáveis: idade, escolaridade, adequabilidade material, epitélios representados, microbiologia e alterações celulares detectadas ao exame citopatológico foram selecionadas. A faixa etária entre 25 a 29 anos ensino...
This study evaluated the effect of green propolis extract on adhesion and biofilm formation Candida species in dentistry materials. Phytochemical analysis was performed by high-performance liquid chromatography. Adhesion quantified counting number yeast cells adherent to dental material fragments a Neubauer chamber. Biofilm determined colony-forming units recovered from fragments. The intensity classified as negative, weak, moderate, strong, or very strong. Fifteen compounds, mainly...
Euterpe oleracea Mart. (açai) is a native palm from the Amazon region. There are various chemical constituents of açai with bioactive properties. This study aimed to evaluate composition and cytotoxic effects seed extract on breast cancer cell line (MCF-7). Global Natural Products Social Molecular Networking (GNPS) was applied identify compounds present in extract. LC-MS/MS molecular networking were employed detect phenolic açai. The antioxidant activity measured by DPPH assay. MCF-7...
Açaí, Euterpe oleracea Mart., is a native plant from the Amazonian and rich in several phytochemicals with anti-tumor activities. The aim was to analyze effects of açaí seed oil on colorectal adenocarcinoma (ADC) cells. In vitro analyses were performed CACO-2, HCT-116, HT-29 cell lines. strains treated for 24, 48, 72 h, viability, death, morphology analyzed. Molecular docking evaluate interaction between major compounds Annexin A2. viability assay showed cytotoxic effect Acai induced...
Realizou-se estudo prospectivo com 1.520 indivíduos menores de 15 anos no Município São José Ribamar, Maranhão, Brasil, junho 1994 a janeiro 1995, o objetivo avaliar prevalência e as características (fatores sócio-econômicos, ambientais hábitos vida) associadas à infecção por Leishmania chagasi. Intradermorreação Montenegro (IDRM) sorologia Enzyme Linked Immunosorbant Assay (ELISA-rK39 CRUDE). Na análise estatística foi utilizado teste chi2 correção Yates, sendo considerado significante um...
To analyse the antineoplastic activity of fractions derived from hydroalcoholic extract Euterpe oleracea Mart. seed in MCF-7 cell line and to identify compounds responsible for action.Cells were treated with 10, 20, 40 60 μg/ml hexane, chloroform ethyl acetate fraction (EAF) açaí seed, 24 48 h. After treatment, viability was measured using MTT assay death assessed Annexin-Pi assay. The most cytotoxic under study analysed by mass spectrometry an electrospray ionization source a cyclotron...
Introduction: This study aimed to identify airborne fungi in São Luis, Maranhão, Brazil, determine the prevalent genera and correlate these with area season. Methods: In total, 1,510 colony-forming units (CFUs) of were isolated from north, south, east west sides center city January December 2007. The samples collected on Petri dishes that exposed by gravitational method. Results: Twenty isolated; most common Aspergillus (33.5%), Penicillium (18.8%), Cladosporium (14.2%), Curvularia (10.6%)...
ABSTRACT Objective: To investigate how mothers of children with congenital syndrome (microcephaly) associated Zika virus perceive their quality life. Methods: This is a qualitative study carried out in two stages: at the Maternal and Child University Hospital Casa de Apoio Ninar through semi-structured interviews virus. Ten women comprised sample. Results: In line critical discourse analysis, four categories emerged based on Fairclough’s 2008 assumptions: Quality Life Health - life...
Infection with human T-lymphotropic virus 1 or 2 (HTLV-1/2) is a major health problem. There public policy defining measures for state hematology and hemotherapy centers in Brazil, order to avoid transmission through blood donors. This study aimed evaluate the seroprevalence of HTLV-1/2 donors State Maranhão, during routine unit screening. Screening tests using enzyme-linked immunosorbent assay (ELISA) detect seropositivity performed at Hematology Hemotherapy Center Maranhão (HEMOMAR)...
Climacteric women are susceptible to a number of changes, among them osteoporosis. Osteoporosis is disease characterized by low bone mass and susceptibility fracture. Currently, this public health issue, being necessary recognize its risk factors.Identify factors related osteoporosis in attending PROPIS/PROEX/UFMA, tracing socio-demographic characterization considering community lifestyles.This transversal retrospective clinical with quantitative approach study conducted between March June...
Euterpe oleracea (açaí) fruit has approximately 15% pulp, which is partly edible and commercialized, 85% seeds. Although açaí seeds are rich in catechins-polyphenolic compounds with antioxidant, anti-inflammatory, antitumor effects-almost 935,000 tons/year of discarded as industrial waste. This work evaluated the properties E. vitro vivo a solid Ehrlich tumor mice. The seed extract presented 86.26 ± 0.189 mg catechin/g extract. palm pulp extracts did not exhibit activity, while showed...
The babassu palm tree is native to Brazil and most densely distributed in the Cocais region of state Maranhão, northeastern Brazil. In addition industrial use refined oil, milk, unrefined oil nuts natura are used by families from several communities African descendants as one principal sources food energy. objective this study was evaluate effects on microvascular permeability leukocyte-endothelial interactions induced ischemia/reperfusion using hamster cheek pouch microcirculation...
The present study aimed to investigate the impact of a short-term exercise training (ET) on cardiorespiratory fitness and autonomic modulation women with breast cancer who were receiving adjuvant radiotherapy, chemotherapy or hormonotherapy. Eighteen previously diagnosed hormone therapy randomly allocated into nonexercise (BC) groups (BC+Ex). Moreover, nine healthy physically inactive volunteers recruited compose noncancer control group (CG). BC+Ex was underwent combined ET program, which...
Objetivo: Verificar, na mais recente literatura, o efeito dos bicos artificiais, como mamadeiras e chupetas, sobre a prática do aleitamento materno. Métodos: Foi realizada uma revisão da literatura nas bases de dados LILACS, SciELO PubMed, considerando estudos originais publicados entre os anos 2010 2015, em português inglês, utilizando-se descritores “chupetas”, “amamentação”, “mamadeiras”, “desmame” “alimentação artificial”, combinados ou isolados, com seus respectivos correspondentes...
INTRODUCTION: Visceral leishmaniasis (VL) and human immunodeficiency virus/acquired syndrome (HIV/AIDS) co-infection has been a research topic of interest worldwide. In Brazil, it observed that there is relative underreporting failure in the understanding management this important association. The aim study was to analyze epidemiological clinical aspects patients with VL without HIV/AIDS. METHODS: We conducted an observational analytical followed Reference Service State Maranhão, Brazil from...
Candida parapsilosis is one of the main species that able to adhere forming biofilms on inert materials. Adhesion first step towards colonization and invasion host cells during infectious process. Among infections, vulvovaginal candidiasis increasingly common. The objective was evaluate profile adherence biofilm formation eight isolates C. metal used in intrauterine devices (IUDs).Eight strains presenting strong adhesion properties were isolated from vaginal secretions a previous study. To...
Cardiovascular diseases are leading causes of death worldwide. Recent studies suggest that infection by some viruses, including the human papillomavirus (HPV), may increase risk developing atheromatous lesions on coronary arteries. However, there is a lack data regarding possible association between HPV and artery disease (CAD) in women.