A5102803482- Microbial Natural Products and Biosynthesis
- Fungal Biology and Applications
- Bee Products Chemical Analysis
- Phytochemistry Medicinal Plant Applications
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Bioactivity Studies
- Insect and Pesticide Research
- Monoclonal and Polyclonal Antibodies Research
- Tannin, Tannase and Anticancer Activities
- Seaweed-derived Bioactive Compounds
- Antifungal resistance and susceptibility
- Soil Management and Crop Yield
- Bacteriophages and microbial interactions
- Toxin Mechanisms and Immunotoxins
- Mycotoxins in Agriculture and Food
- Plant Virus Research Studies
- Phytochemicals and Antioxidant Activities
- Cancer Cells and Metastasis
- Enzyme Catalysis and Immobilization
- Microbial Metabolism and Applications
- Advancements in Transdermal Drug Delivery
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Cancer Research and Treatments
Universidade Federal do Maranhão
2020-2024
Anticancer Fund
2024
This study evaluated the effect of green propolis extract on adhesion and biofilm formation Candida species in dentistry materials. Phytochemical analysis was performed by high-performance liquid chromatography. Adhesion quantified counting number yeast cells adherent to dental material fragments a Neubauer chamber. Biofilm determined colony-forming units recovered from fragments. The intensity classified as negative, weak, moderate, strong, or very strong. Fifteen compounds, mainly...
Abstract Background This study evaluated the influence of green propolis’ extract on adhesion and biofilm formation Candida species dentistry material. Methods Phytochemical analysis was performed by High Performance Liquid Chromatography. Adhesion quantified in a Neubauer chamber, counting number yeast cells adhered to fragments; Biofilm determined colony forming units (CFU). The intensity classified as negative, weak, moderate, strong very strong. Fifteen compounds were identified propolis...
This study addresses the antitumoral properties of Penicillium purpurogenum isolated from a polluted lagoon in Northeastern Brazil.Ethyl Acetate Extracellular Extract (EAE) was used. The metabolites were studied using direct infusion mass spectrometry. solid Ehrlich tumor model used for antitumor activity. Female Swiss mice divided into groups (n = 10/group) as follows: negative control (CTL-), treated with phosphate buffered solution; positive (CTL+), cyclophosphamide (25 mg/kg); extract...
To evaluate the biological activities of secondary metabolites obtained from Fusarium species. The oxysporum showed a proliferative effect on MCF-7 cells. solani reduced viability cell in 48 hours. both fungi significant antibacterial activity (p<0.0010) E. coli strains at all concentrations. F.oxysporum and significantly inhibited S. aureus concentrations within 24h. F. C. albicans (p<0.0001) There are compounds with antitumor antimicrobial properties.
Este artigo objetiva avaliar os fenólicos totais e a atividade antioxidante do extrato preparado fungo Penicillium purpurogenum, obtido de um ambiente marinho poluído São Luís-MA. A pesquisa foi realizada na Laguna da Jansen localizada no município Luís, Maranhão, Brasil. Foram realizadas 4 coletas sedimento período maio setembro 2017, matutino. As amostras foram obtidas uma profundidade até 73,5 cm com auxílio draga metálica. identificação seguiu metodologias isolamento posterior preparo...
Este artigo objetiva o isolamento, identificação e triagem fitoquímica de um extrato preparado do fungo Penicillium purpurogenum, obtido ambiente marinho poluído São Luís-MA. A pesquisa foi realizada na Laguna da Jansen localizada no município Luís, Maranhão, Brasil. Foram realizadas 4 coletas sedimento período maio a setembro 2017, matutino. As amostras foram obtidas uma profundidade até 73,5 cm com auxílio draga metálica. seguiu metodologias isolamento dos extratos preparados por...
Talaromyces purpurogenus is a fungus species widely found in the marine environment. When hostile environment, it produces series of secondary metabolites with important biotechnological potential, such as meroterpenoids. In our previous report, we demonstrated that culture broth ethyl acetate extract from T. reduced cellular infiltration lymphoid organs and circulating levels TNF-α. To elucidate this anti-inflammatory effect, work aimed to study isolated marine-polluted environment...
Background: Species of mycotoxin-producing fungi are potentially dangerous to humans and animals. The liver is the best-known organ action these substances. aim this study was isolate microscopic from honey investigate cytotoxic effect extract Penicillium sp. in an experimental model. Methods: Honey samples were cultured Sabouraud agar. After isolated identified microscopically, colonies genus transplanted dextrose agar culture medium. its development, they processed obtain extract. Eighteen...
ABSTRACT The interest in red colorants by the food industry has been increasing recently due to its wide application many foods and beverages, also carcinogenic teratogenic effects of some synthetic dyes. Many ascomycetous fungi are able synthesize produce pigments, rendering them as alternative sources natural dyes that independent environmental conditions. Talaromyces islandicus TI01 was isolated from a marine-influenced environment suffering for decades anthropogenic actions body water....
ABSTRACT Background The bioactive metabolites production contributes to the resistance of fungi towards adverse environmental conditions. Some often have interesting health-promoting activities. This study addressed anti-tumoural properties Penicillium purpurogenum isolated from a polluted lagoon in Northeastern Brazil. Methods extract obtained polished environment strain P. was fermented, filtered, concentrated and lyophilized, giving rise Ethyl Acetate Extracellular Extract (EAE)....
Talaromyces islandicus TI01 was isolated from a marine-influenced environment that has been suffering for decades anthropogenic actions in its body of water.Broth microdilution technique performed to analyze the antimicrobial activity.For analysis cytotoxic activity, MTT [3-(4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide] assay conducted.The chemical extract by LC/MS (liquid chromatography coupled mass spectrometry).The minimum bactericidal concentration (MBC) T. E. coli ATCC...