A5000741710- Antifungal resistance and susceptibility
- Women's cancer prevention and management
- Fungal Infections and Studies
- Tuberculosis Research and Epidemiology
- Mosquito-borne diseases and control
- Public Health in Brazil
- Science and Education Research
- Health Education and Validation
- Antibiotic Resistance in Bacteria
- Nail Diseases and Treatments
- Reproductive tract infections research
- Maternal and Neonatal Healthcare
- Cervical Cancer and HPV Research
- Healthcare Regulation
- Vibrio bacteria research studies
- Urinary Tract Infections Management
- Syphilis Diagnosis and Treatment
- Probiotics and Fermented Foods
- Gut microbiota and health
- Bacterial biofilms and quorum sensing
- Pneumocystis jirovecii pneumonia detection and treatment
- Indoor Air Quality and Microbial Exposure
- Salivary Gland Disorders and Functions
- Oral and gingival health research
- Viral Infections and Vectors
Universidade Federal do Maranhão
2014-2025
Centro Universitário do Maranhão
2011-2020
Universidade do Estado do Rio de Janeiro
2017
Universidad Filadelfia de México
2014
Instituto Federal do Maranhão
2013
Many Clostridium species are found as commensal members of the intestinal microbiota. However, imbalances microbiota may lead to certain infections caused by these microorganisms, mainly butyricum, difficile, and perfringens. In many cases, infection recurrence can occur after antibiotics, indicating need for novel therapeutic options that act on pathogens also restore Herein, in vitro antimicrobial activity probiotic potential clinical reference strains Bifidobacterium Lactobacillus were...
Candida yeasts are commensals; however, if the balance of normal flora is disrupted or immune defenses compromised, species can cause disease manifestations. Several attributes contribute to virulence and pathogenicity Candida, including production extracellular hydrolytic enzymes, particularly phospholipase proteinase. This study aimed investigate in vitro activity phospholipases acid proteinases clinical isolates spp.Eighty-two from hospitalized patients collected various sites origin were...
Candida yeasts are generally found in the vaginal microbiota; however, disruption of balance maintained by host factors and microorganisms results vulvovaginal candidiasis (VVC). This study evaluated antagonistic activity Lactobacillus spp. on albicans to verify whether active compounds had antifungal antivirulence activity. The antagonism assay showed that 15 out 20 strains an inhibitory effect C. albicans. Biosurfactants displayed surface-tension-reducing activity, with best value obtained...
Abstract Background Ventilator-associated pneumonia (VAP) is considered the most common nosocomial infection in intensive care unit (ICU), but its features are not fully known many hospitals Brazil. We identified clinical and epidemiological aspects associated with VAP an (ICU) a general public hospital northern Brazil performed analytical descriptive prospective cohort study. Methods analyzed data from thirty-three patients who developed while ICU. Clinical of were obtained tracheal...
Limosilactobacillus fermentum (ATCC 23271) was originally isolated from the human intestine and has displayed antimicrobial activity, primarily against Candida species. Complete genome sequencing comparative analyses were performed to elucidate genetic basis underlying its probiotic potential. The ATCC 23271 found contain 2,193,335 bp, with 2123 protein-coding sequences. Phylogenetic analysis revealed that strain shares 941 gene clusters six other strains of L. fermentum. Putative genes...
Streptococcus agalactiae (Streptococcus do Grupo B; EGB) é considerado o agente etiológico mais importante de infecções neonatais invasivas, principalmente sepse e meningite, em bebês menores 3 meses. Este estudo teve por objetivo isolar EGB a partir amostras secreções vaginais anorretais gestantes; identificar as características moleculares determinar suscetibilidade antimicrobiana dos isolados. As foram coletadas 200 gestantes atendidas uma clínica pré-natal alto risco São Luís-Maranhão....
Bacteria that produce Klebsiella pneumoniae carbapenemases (KPCs) are resistant to broad-spectrum β-lactam antibiotics. The objective of this study was phenotypically and genotypically characterize the antibiotic susceptibility carbapenems 297 isolates recovered from clinical samples obtained inpatients at 16 hospitals in São Luis (Maranhão, Brazil). conducted using phenotypic tests molecular methods, including polymerase chain reaction (PCR), sequencing enterobacterial repetitive intergenic...
Patients with rheumatoid arthritis (RA) suffer from pain and joint disability. The transient receptor potential ankyrin 1 (TRPA1) channel expressed on sensory neurones non-neuronal cells mediates transduction inflammation it has been implicated in RA. However, there is little information the contribution of TRPA1 for human disease. Here, we investigated expression peripheral blood leukocytes circulating levels its endogenous activators 4-hydroxynonenal (4-HNE) hydrogen peroxide (H2O2) RA...
Background/Objectives: Antifungal resistance to azoles, coupled with the increasing prevalence of Candida albicans infections, represents a significant public health challenge and has driven search for new natural compounds that can act as alternatives or adjuvants current antifungals. Ellagic acid (EA) demonstrated antifungal activity; however, its effects are not fully understood. In this study, we investigated in vitro anti-Candida activity EA ability potentiate fluconazole (FLZ) on C....
A cobertura vacinal nos chamados "países em desenvolvimento" ainda está aquém da esperada. Ela é um importante indicador de saúde das populações e qualidade atenção dispensada pelos serviços. O presente estudo descreve os resultados inquérito domiciliar para estimar a do esquema básico o primeiro ano vida nas capitais Nordeste brasileiro, coorte nascida 2005. metodologia usada preconizada pela Organização Pan-Americana Saúde realização inquéritos vacinal. Os dados obtidos no demonstram que...
Introduction: This study aimed to identify airborne fungi in São Luis, Maranhão, Brazil, determine the prevalent genera and correlate these with area season. Methods: In total, 1,510 colony-forming units (CFUs) of were isolated from north, south, east west sides center city January December 2007. The samples collected on Petri dishes that exposed by gravitational method. Results: Twenty isolated; most common Aspergillus (33.5%), Penicillium (18.8%), Cladosporium (14.2%), Curvularia (10.6%)...
OBJETIVOS/MÉTODOS: Avaliou-se a condição periodontal de 30 pacientes, em hemodiálise, através do índice placa, gengival, cálculo, PSR e quantidade IgA na saliva, visando determinar doentes renais crônicos. RESULTADOS: Os resultados demonstraram que os índices gengival calculo foram considerados altos nestes pacientes. Com relação à necessidade tratamento periodontal, observou-se maior parte dos pacientes hemodiálise precisava medidas higiene bucal, raspagem supra subgengival fluoretação...
Candida parapsilosis is one of the main species that able to adhere forming biofilms on inert materials. Adhesion first step towards colonization and invasion host cells during infectious process. Among infections, vulvovaginal candidiasis increasingly common. The objective was evaluate profile adherence biofilm formation eight isolates C. metal used in intrauterine devices (IUDs).Eight strains presenting strong adhesion properties were isolated from vaginal secretions a previous study. To...
Trata-se de uma investigação amostral com 843 entrevistados, realizado no Município São Luís, Maranhão, Brasil. Avaliou-se o conhecimento da população sobre dengue, assim como suas condições sócio-econômicas, sanitárias e ambientais. Verificaram-se criadouros potenciais em toda a área pesquisada. A mídia (TV, rádio etc.) foi meio comunicação mais importante fonte informação doença para população. No entanto, observou-se lacuna entre prática atitudes voltadas evitar proliferação do mosquito...
Objective: To assess salivary biomarkers for dental caries susceptibility and mental stress in young adults with perceived facial pain.Methods: Males females who reported pain pain-free controls participated this study. Facial was investigated using the RDC/TMD. Unstimulated saliva then collected evaluation of flow rate (SFR), pH, Streptococcus mutans counts, morning cortisol, S-IgA.Results: Women had significantly lower SFR values, group showed different correlations among cortisol levels...
Antisepsis of the hands medical personnel is one most important steps in process patient care, since direct contact can cause cross-transfer potentially pathogenic microorganisms at surgical sites. This study aimed to analyze prevalence on 131 surgeons a university hospital before procedure. Swabs were collected from each clinician's and after handwashing. The samples placed transport medium immediately delivered private clinical analysis laboratory São Luis-Maranhão. identified by...
To determine the frequency of human papillomavirus (HPV) types and behavioral characteristics related to cytological abnormalities in women descendants slaves, who live isolated communities known as quilombos state Maranhão, Brazil.Cervicovaginal specimens 353 were analyzed by conventional cytology genotyping. HPV detection genotyping was performed using a linear array test kit. Behavioral factors their association with analyzed, well between infection.The infection 13%, high-risk more...
This study aimed to determine the prevalence and antimicrobial resistance of pathogens involved in urinary tract infections diagnosed a private laboratory São Luis, MA. Were analyzed 875 (37%) positive urine cultures performed from January 2005 June 2008. The agents found were separated into three major groups, Enterobacteria predominated among isolates 85.5% samples ( Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter aerogenes e Serratia marcenses ). Cocos Gram -...
Rigorous control of water quality in hemodialysis services is extremely important order to guarantee a better life the patients submitted this treatment. The lack adequate monitoring has caused death various past. objective present study was determine physicochemical and bacteriological characteristics used by hospitals city São Luís, Maranhão, Brazil. Bacteriological analyses included membrane filter method for determination total coliform bacteria, Cult-Dipcombi-TTC-agar heterotrophic...
Sickle cell anaemia is one of the most common hemoglobinopathies worldwide and an important public health problem in Brazil. This study evaluated prevalence sickle its traits newborns from Amazon-Savanna Transition Region state Maranhão, A cross-sectional was carried out, based on data neonatal screening tests performed 2013-2015 Maranhão. The Hardy-Weinberg theorem applied to analyse frequency expected homozygotes HbSS phenotype. spatial-temporal distribution analysis delimit regions with...