A5030836962- Antimicrobial Peptides and Activities
- Wound Healing and Treatments
- Escherichia coli research studies
- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Antibiotic Resistance in Bacteria
- Healthcare during COVID-19 Pandemic
- Psychology and Mental Health
- Vitamin K Research Studies
- Reproductive tract infections research
- Vaccine Coverage and Hesitancy
- Apelin-related biomedical research
- Neuropeptides and Animal Physiology
- Vibrio bacteria research studies
- Antimicrobial agents and applications
- Viral gastroenteritis research and epidemiology
- Clostridium difficile and Clostridium perfringens research
- Microbial Metabolism and Applications
- Syphilis Diagnosis and Treatment
- Advancements in Transdermal Drug Delivery
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Piperaceae Chemical and Biological Studies
- T-cell and Retrovirus Studies
- Diphtheria, Corynebacterium, and Tetanus
- Bacterial biofilms and quorum sensing
Centro Universitário do Maranhão
2012-2025
Universidade Federal da Grande Dourados
2024
Universidade Federal do Maranhão
2016-2024
Women's Hospital
2013
Cinnamaldehyde is a natural essential oil suggested to possess anti-bacterial and anti-inflammatory properties; activate transient receptor potential ankyrin 1 (TRPA1) channels expressed on neuronal non-neuronal cells. Here, we investigated the immunomodulatory effects of cinnamaldehyde in an vivo model systemic inflammatory response syndrome (SIRS) induced by lipopolysaccharide. Swiss mice received single oral treatment with h before LPS injection. To investigate whether are dependent TRPA1...
Bacterial resistance to the available marketed drugs has prompted search of novel therapies; especially in regards anti-virulence strategies that aim make bacteria less pathogenic and/or decrease their probability become resistant therapy. Cinnamaldehyde is widely known for its antibacterial properties through mechanisms include interaction this compound with bacterial cell walls. However, only a handful studies have addressed effects on virulence, when tested at sub-inhibitory...
Escherichia coli and Staphylococcus aureus are important agents of urinary tract infections that can often evolve to severe infections. The rise antibiotic-resistant strains has driven the search for novel therapies replace use or act as adjuvants antibiotics. In this context, plant-derived compounds have been widely investigated. Cuminaldehyde is suggested major antimicrobial compound cumin seed essential oil. However, effect not fully understood. Herein, we investigated in silico vitro...
Lactobacilli are involved in the microbial homeostasis female genital tract. Due to high prevalence of many bacterial diseases tract and resistance microorganisms various antimicrobial agents, alternative means control these infections necessary. Thus, this study aimed evaluate probiotic properties well-characterized Lactobacillus species, including L. acidophilus (ATCC 4356), brevis 367), delbrueckii ssp. 9645), fermentum 23271), paracasei 335), plantarum 8014), rhamnosus 9595), against...
Wound healing can be delayed following colonization and infection with the common bacterium Pseudomonas aeruginosa. While multiple therapies are used for their treatment, these ineffective, expensive, labour-intensive. Thus, there is an enormous unmet need treatment of infected wounds. Cinnamaldehyde, major component cinnamon oil, well known its antimicrobial properties. Herein, we investigated effects sub-inhibitory concentrations cinnamaldehyde in virulence P. We also assessed potential...
Pseudomonas aeruginosa has caused high rates of mortality due to the appearance strains with multidrug resistance (MDR) profiles. This study aimed characterize molecular profile virulence and genes in 99 isolates P. recovered from different clinical specimens. The were identified by automated method Vitek2, antibiotic susceptibility was determined using classes antimicrobials. genomic DNA extracted amplified multiplex polymerase chain reaction (mPCR) detect antimicrobial genes. Molecular...
A obesidade é um problema de saúde global, e muitas pessoas buscam plantas medicinais como alternativa para perda peso, devido aos efeitos colaterais dos medicamentos tradicionais. No entanto, o uso irracional dessas pode apresentar riscos, pois algumas podem substâncias tóxicas. Este estudo avaliou os na mutagenicidade, anti- mutagenicidade proliferação celular. pesquisa foi experimental qualitativa, utilizando populares no mercado emagrecimento, hibisco, chá verde, gengibre, entre outras....
Enteroaggregative (EAEC) and atypical enteropathogenic (EPEC) Escherichia coli are important bacterial etiologic agents causing diarrhea among children. The aim of the present study was to examine impact virulence factors predisposes diarrhea. In this some properties were examined on 11 EAEC 8 EPEC strains identified by Polymerase Chain Reaction (PCR), isolated from stool samples children analyzed genotypically phenoltypically for prevalence factors. most frequently detected factor...
Vulvovaginal candidiasis (VVC) ranks second among causes of vaginitis. Candida albicans is responsible for the majority symptomatic episodes VVC. However, one fact to consider increase infections by species non-C. albicans, which contribute high rates recurrence and resistance. The purpose this study was isolate spp. samples from vaginal discharge, determine prevalence assess production hydrolytic enzymes (proteases,phospholipases, hemolysins, catalase, gelatinases) in clinical isolates. 144...
O presente estudo teve por objetivo relacionar a incidência do dengue com variáveis demográficas, temporais e meteorológicas, fim de identificar as áreas mais elevadas incidências determinar os sorotipos prevalentes, no período 2002 a2012, Município São Luís, MA. Os dados foram extraídos dos boletins casos até então notificados, disponíveis na Secretaria Municipal Saúde Vigilância Epidemiológica Sanitária Foi calculada estatística descritiva para todas relevantes, como idade, sexo, condições...
The city of São Luís, capital Maranhão state (Brazil), provides ineffective treatment its effluents, which are released straight into the water resources. In order to search for indicators fecal contamination at coastal environment we collected samples from different sites. Samples Ponta d'Areia, Marcos, Calhau and Olho d'Água beaches were analyzed aiming detect pathogens diarrheagenic strains Escherichia coli; in addition test susceptibility E. coli sanitizer agents. all areas, species...
The production of ESBL is an important mechanism resistance to ?-lactam antimicrobials. wide use antibiotics in the treatment urinary tract infections (UTI) has further aggravated this problem. Bacteria UPEC type are main responsible for kind infection. Studies understand diversity Brazil scarce and, addition, many them directed nosocomial samples. objective study was detect genes encoding ?-lactamases TEM, SHV and CTX-M through multiplex PCR, as well identify isolates that produce...
Infecção de feridas, principalmente as crônicas, é um problema para a saúde pública mundial. A papaína vem sendo utilizada como cobertura realização desbridamento enzimático, porém seu uso agente antmicrobiano ainda se mostra incerto. Deste modo, o objetivo desta pesquisa foi avaliar atividade antimicrobiana da e sua associação com ureia. Para isto foram utilizadas cepas: Pseudomonas aeruginosa ATCC 27853, Escherichia coli 042, Staphylococcus aureus 6538, Klebsiella pneumoniae 700603...
A aromaterapia é uma técnica milenar que visa promover a saúde física, mental e emocional do indivíduo mediante o uso de óleos essenciais (OE) provenientes plantas aromáticas, oferecem inúmeros benefícios terapêuticos, podendo assim auxiliar na prevenção, tratamento controle dos transtornos mentais como ansiedade. Com isso, este trabalho objetivou avaliar utilização para da ansiedade, bem seus benefícios, frequência tipos mais empregados no visando minimizar quadros ansiedade colaborar...
Biofilm in chronic wound is an important public health problem several countries due its delayed healing and ineffective local treatment. Several treatments are employed to inhibit bacterial growth, among which polyhexamethylene biguanide (PHMB) stands out. PHMB widely known for antibacterial properties through mechanisms that include the interaction of this compound with cell walls DNA. However, there conflicting data regarding activity eradicating mature biofilm. The purpose study was...
As vacinas representam uma das mais importantes ferramentas disponíveis para a prevenção de doenças. Além da proteção individual contra sérias doenças, elas também protegem comunidade reduzindo circulação agentes infecciosos. O objetivo deste estudo foi verificar situação vacinal crianças menores dois anos atendidas em um centro saúde no município Raposa Estado do Maranhão. é tipo descritivo, prospectivo, com abordagem quantitativa dos dados.Obteve-se amostra 95 quais 45% (n=43) estavam...