A5101510816- Advanced Radiotherapy Techniques
- Cardiomyopathy and Myosin Studies
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Biomedical and Engineering Education
- Galectins and Cancer Biology
- Lipoproteins and Cardiovascular Health
- Noise Effects and Management
- Artificial Intelligence in Healthcare
- Machine Learning in Healthcare
- Hearing, Cochlea, Tinnitus, Genetics
- Ferroptosis and cancer prognosis
- Cancer, Hypoxia, and Metabolism
- Ion channel regulation and function
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Reproductive tract infections research
- Drug Transport and Resistance Mechanisms
- Cardiac electrophysiology and arrhythmias
- Effects of Environmental Stressors on Livestock
- Mitochondrial Function and Pathology
- Climate Change and Health Impacts
- Cervical Cancer and HPV Research
- Antioxidant Activity and Oxidative Stress
- Congenital heart defects research
- Protein Tyrosine Phosphatases
Chinese PLA General Hospital
2022
Guangxi Medical University
2021
Hangzhou Normal University
2019
Shihezi University
2017-2019
Iowa State University
2018
Georgetown University
2011-2015
Georgetown University Medical Center
2011
Harvard University
2007
Chinese General Hospital College of Nursing and Liberal Arts
2007
Catecholamine-induced polymorphic ventricular tachycardia (CPVT) is a familial disorder caused by cardiac ryanodine receptor type 2 (RyR2) or calsequestrin (CASQ2) gene mutations. To define how CASQ2 mutations cause CPVT, we produced and studied mice carrying human D307H missense mutation (CASQ307/307) CASQ2-null (CASQΔE9/ΔE9). Both identical consequences. Young mutant had structurally normal hearts but stress-induced arrhythmias; aging hypertrophy reduced contractile function. Mutant...
Heat stress (HS) jeopardizes animal productivity and health. The intestinal barrier is sensitive to HS heat-induced hyperpermeability plays a key role in its pathophysiology. However, the biology of recovery following less understood. Thus, study objectives were determine temporal pattern metabolic, inflammatory, histological parameters during recovery. Female pigs (n = 32; 19.5 ± 0.5 kg BW) sacrificed exposure 1 4 environmental treatments: 1) constant thermoneutral (TN) conditions (TNC;...
Purpose: To investigate associations for polymorphisms in β-carotene 9',10'-oxygenase (BCO2, rs10431036 and rs11214109), proprotein convertase subtilisin kexin type 9 (PCSK9, rs11583680), tribbles pseudokinase 1 (TRIB1, rs17321515 rs2954029), as well lifestyle factors, with ischemic stroke (IS).Materials Methods: This nested case-control study included 161 patients IS 483 matched control individuals.We collected medical reports, details, blood samples from individuals used the PCR-ligase...
Coronary artery disease has become a major health concern over the past several decades. We aimed to explore association of single nucleotide polymorphisms (SNPs) in ATP-binding cassette subfamily A member 1 (ABCA1) and lifestyle factors with coronary (CAD) dyslipidemia. This nested case-control study included 173 patients CAD 500 matched control individuals (1:3, case: control) from district southern China. collected medical reports, details, blood samples dyslipidemia used polymerase chain...
Unfavorable serum lipid levels are the most important risk factors for coronary artery disease (CAD), cerebral infarction, and other cardiovascular cerebrovascular diseases. This study included 2323 Han Chinese in southern China. We collected medical reports, lifestyle details, blood samples of individuals used polymerase chain reaction-ligase detection reaction method to genotype single-nucleotide polymorphisms (SNPs). Two SNPs showed a strong evidence association with total cholesterol...
Objective: To investigate the correlations of laminin subunit gamma 3 (LAMC3) expression with prognosis ovarian cancer (OC). Methods: LAMC3 protein was measured using immunohistochemical streptavidin-peroxidase-biotin connection method (IHC). Gene and related clinical data in genome atlas (TCGA) cohort proteomic tumor analysis consortium (CPTAC) were applied to analyse correlation between gene expressions outcomes. Correlations clinicopathological factors evaluated Pearson χ2 test (2-sided)....
e15134 Background: Clinical data suggest that fewer large fractions are radio-biologically superior to smaller fraction sizes in prostate cancer radiotherapy. The CyberKnife is the ideal delivery system for hypofractionated radiosurgery due its ability deliver highly conformal radiation and track adjust motion real-time. We report our early experience using radiotherapy localized cancer. Methods: Thirty nine patients were treated with robotic or without supplemental external therapy and/or...
High-risk human papillomavirus type 16 (HPV16) is a risk factor for cervical cancer. The progression from initial infection to cancer has been linked properties of the viral sequences. However, distribution HPV16 variants among Chinese women not extensively addressed and role in carcinogenesis remains poorly understood.HPV16 positive exfoliated cell samples were collected 249 living Beijing, China. PCR products two fragments E6-E7 LCR these sequenced analyzed.Lineage A was found subjects,...