A5101553394- Virus-based gene therapy research
- Spine and Intervertebral Disc Pathology
- Anesthesia and Pain Management
- Neurosurgical Procedures and Complications
- Immunotherapy and Immune Responses
- Vascular Tumors and Angiosarcomas
- Viral Infectious Diseases and Gene Expression in Insects
- Radiopharmaceutical Chemistry and Applications
- Proteoglycans and glycosaminoglycans research
- Prenatal Screening and Diagnostics
- Urinary Tract Infections Management
- Vector-Borne Animal Diseases
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Chemokine receptors and signaling
- Obesity and Health Practices
- Stress Responses and Cortisol
- Medical Education and Admissions
- Congenital Anomalies and Fetal Surgery
- Ear and Head Tumors
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Oral and Maxillofacial Pathology
- Cleft Lip and Palate Research
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
Newcastle University
2015
Oregon Health & Science University
2015
University College London
1993-2002
The Royal Free Hospital
1993-2002
University of Utah
2001
Birmingham City University
1996-1998
University of Toronto
1961
Hospital for Sick Children
1961
Certain glycosaminoglycans (GAGs), including heparin, inhibit infection by murine leukemia virus (MLV). We now show that this is due to inhibition of attachment independent the interaction between viral envelope proteins (Env) and their cellular receptors. Heparin blocked binding both Env-deficient amphotropic MLV (MLV-A) particles NIH 3T3 fibroblasts, CHO cells which lack retroviral receptor Pit-2, transfected with Pit-2 (CHO-Pit-2). also inhibited transduction MLV-A over a similar...
Journal Article Powassan Virus: Investigations of Possible Natural Cycles Infection Get access Donald M. McLean, McLean From the Research Institute The Hospital for Sick Children, Toronto; University Toronto School Hygiene, from Department Zoology, Ontario Agricultural College, Guelph, Canada Search other works by this author on: Oxford Academic PubMed Google Scholar Selma J. Walker, Walker Lachlan W. Macpherson, Macpherson Theodorus H. Scholten, Scholten Keith Ronald, Ronald John C. Wyllie,...
To determine the prevalence of aneuploidy and additional major anatomic abnormalities in fetuses neonates with cleft lip or without palate. All cases palate (cleft lip/cleft palate) occurring Utah from 1995 through 1999 were reviewed by using Birth Defect Network population‐based surveillance system. pregnancy outcomes are included (stillborn, live born, termination) this analysis. Of 263 palate, 72 (27.4%) unilateral lip, 112 (42.6%) 12 (4.6%) bilateral 67 (25.5%) Fifteen (5.7%) aneuploid....
There is increasing recognition in medicine of the importance noncognitive factors, including personality, for performance, and good medical practice. The personality domain conscientiousness a well-established predictor performance workplace academic settings. This study investigates relationships between "Big Five" domains, facets practical anatomy examination. First- second-year undergraduate students (n = 85) completed paper-based questionnaire, which included 50-item measure Big Five...
The aim of this study was to quantify the impact amphotropic retroviral receptor (PiT-2) levels on susceptibility transduction and determine whether low level PiT-2 found CD34+ hematopoietic cells is within range likely compromise gene transfer. Receptor-deficient Chinese hamster ovary (CHO) were transfected with a construct that could be induced by removal tetracycline. expression measured virus binding in uninduced fully partially transfectants correlated efficiency an reporter vector....
Summary. Using the p38 stress‐activated protein kinase (p38SAPK) inhibitor, SB203580, increased responsiveness of monocyte‐derived dendritic cells (MoDCs) to secondary lymphoid chemokine (SLC) and macrophage inflammatory 3β (MIP3β), following lipopolysaccharide‐induced MoDC maturation, was shown be mediated by p38SAPK pathway. This due complete abrogation upregulation CC receptor 7, for MIP3β/SLC. Once mature, MoDCs utilized both phosphoinositide‐3 pathways migrate in response SLC or MIP3β....
In patients with a history of recurrent infections, treatment enoxacin (200 mg/12 h for 3 days) relieved symptoms acute urinary infection significantly more rapidly than cefuroxime axetil (125 7 days). Other parameters, including clinical and bacteriological cure rates patients' overall opinion their treatment, did not differ between the treatments.
To the Editor: We wish to comment on Suzuki et al.'s article [1], which suggests that dural puncture without intrathecal injection of local anesthetic in a combined spinal epidural technique increases caudal spread epidurally administered mepivacaine: 1. The study was not blinded, since same anesthesiologist performed and assessed block. 2. Increased is explained by Bernards [2], actually showed flux through hole made 27-gauge Whitacre needle increased. However, did increase after with...