- Cardiac, Anesthesia and Surgical Outcomes
- Patient Safety and Medication Errors
- Burn Injury Management and Outcomes
- Surgical Simulation and Training
- Thermal Regulation in Medicine
- Clinical Reasoning and Diagnostic Skills
- Immune Response and Inflammation
- Innovations in Medical Education
- Medical Malpractice and Liability Issues
- Diverticular Disease and Complications
- Colorectal Cancer Surgical Treatments
- COVID-19 Clinical Research Studies
- Bariatric Surgery and Outcomes
- Wound Healing and Treatments
- Hospital Admissions and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Healthcare cost, quality, practices
- T-cell and B-cell Immunology
- Diet and metabolism studies
- Diabetes Treatment and Management
- Long-Term Effects of COVID-19
- Colorectal Cancer Screening and Detection
- Healthcare Quality and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Artificial Intelligence in Healthcare and Education
Agostino Gemelli University Polyclinic
2025
Istituti di Ricovero e Cura a Carattere Scientifico
2025
Northwell Health
2020-2024
Lenox Hill Hospital
2008-2024
North Shore Diabetes and Endocrine Associates
2024
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2022-2023
Icahn School of Medicine at Mount Sinai
2022
Marcus (United States)
2021-2022
New York Proton Center
2021
Hofstra University
2017
Lipopolysaccharide (LPS, endotoxin) administration to human subjects elicits significant elevations in plasma cachectin/TNF, epinephrine, and cortisol. This study examined the temporal relationship between changes blood leukocyte subsets mediators following endotoxin normal subjects. A five-minute intravenous infusion of purified LPS (20 units/kg Escherichia coli) was administered 12 healthy volunteers. Blood samples were obtained at varying intervals after analyzed for differential cell...
To study the roles of platelet-activating factor, polymorphonuclear leukocytes, and oxygen free radicals in myocardial reperfusion injury, we subjected 10 sheep to 90 minutes mid-left anterior descending coronary artery followed by 6 hours reperfusion. Stainings with gentian violet tetratriphenyl ammonium chloride demonstrated 20% ± 3% left ventricular mass at risk for ischemia, which 75% 10% underwent infarction. Coronary sinus blood was assayed factor neutrophil hydrogen peroxide...
Care Innovations| March 15 2024 Novel Approach to Continuation of Elective Procedures in People at Risk for Sodium–Glucose Cotransporter 2 Inhibitor–Associated Euglycemic Ketoacidosis Matthew Verdone; Verdone 1Northwell, New Hyde Park, NY2Endoscopic and Advanced Endoscopic Anesthesia Services, Long Island Center Digestive Health, Northwell Uniondale, NY Search other works by this author on: This Site PubMed Google Scholar Jonathan Bauman; Bauman NY3Department Anesthesiology, Esben Iversen...
The incidence of long thoracic nerve palsy after radical mastectomy has been documented to be approximately 10%. No cases have reported the more recent treatment for breast cancer, lumpectomy with axillary dissection. This surgical procedure is customarily followed by aggressive radiation therapy remaining tissue. first case report a patient radiation-induced palsy. was young woman who underwent left quadrantectomy and dissection cancer. After therapy, she had isolated diagnosis confirmed...
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) continues to be a global challenge due the lack of definitive treatment strategies. We sought determine efficacy early administration anti-interleukin 6 therapy in reducing hospital mortality and progression mechanical ventilation.This was retrospective chart review 11,512 patients infected with who were admitted New York health system from March May 2020. Tocilizumab administered subjects at nasal cannula level oxygen support...
Thermal injury results in transient elevations of plasma glucocorticoids and promotes translocation bacteria from the gut to mesenteric lymph nodes (MLN) rats. Translocated organisms are quickly cleared following uncomplicated thermal injury. However, subsequent burn wound infection, temporal association with sustained pathophysiologic corticosterone, continued presence enteric MLN. To study role steroid mediation this prolonged bacterial translocation, Wistar rats were randomly placed...
Objectives : U.S. expenditures on medical devices ($70 billion in 2003) are one of the fastest growing components hospital costs. Physicians’ selection lacks an evidence base comparative clinical effectiveness these products. Comparative studies (e.g., vendor 1 versus 2, technology A B) increasingly promoted public sector as a means cost containment, value-based purchasing, and quality improvement. This study illustrates how hospitals physicians can conduct assessments product performance....
During ongoing flow cytometric studies of burned patient blood leukocytes, it was noted frequently that large numbers granulocytes were present along with the mononuclear cells at plasma/Ficoll-Hypaque (F-H) interface following centrifugation over F-H. Since differential WBC counts are not routinely performed on F-H cells, is possible many previous immunologic patients have greatly overestimated lymphocytes recovered. The study sought to quantify extent which granulocyte contamination...
Changes in endocrine status are known to occur following thermal injury. Therefore, the effect of burn injury on plasma corticosteroid and thyroid hormones their respective binding proteins was examined. Thirty-one subjects with 18%-99% TBSA were compared 50 normal controls respect levels total cortisol, free thyroxine (T4), index (FTI), corticosteroidbinding globulin capacity ICBGC), tri-iodothyronine uptake (T3U), albumin. Compared controls, concentrations cortisol thermally injured...
To study the profile of incidents affecting quality outcomes after surgery by developing a usable operating room and perioperative clinical incident report database functional electronic classification, triage, reporting system. Previously, reports were handled on an individual, episodic basis, which limited ability to perceive actuarial patterns meaningfully improve outcomes.Clinical experientially generated in second largest health care system New York City. Data entered into...
The purpose of the present studies was to investigate effect glucocorticoids on catabolism and lymphocyte numbers in a rat model thermal injury or plus burn wound infection. Thermal alone caused only an acute increase plasma corticosterone concentrations. Furthermore, body weight declined moderately (5%), lymph nodes draining blood increased markedly, whereas splenic by about 60%. By contrast uninjured rats subjected chronic elevation pellet implantation showed large decreases all tissues...