A5036432444- Innovations in Medical Education
- Clinical Nutrition and Gastroenterology
- Cardiac, Anesthesia and Surgical Outcomes
- Nutrition and Health in Aging
- Patient Safety and Medication Errors
- Clinical Reasoning and Diagnostic Skills
- Palliative Care and End-of-Life Issues
- Central Venous Catheters and Hemodialysis
- Health and Medical Research Impacts
- Diversity and Career in Medicine
- COVID-19 and healthcare impacts
- Abdominal Surgery and Complications
- Esophageal and GI Pathology
- Cardiac Arrest and Resuscitation
- Ethics in medical practice
- Hip and Femur Fractures
- Advances in Oncology and Radiotherapy
- Frailty in Older Adults
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Inflammation biomarkers and pathways
- Trauma Management and Diagnosis
- Healthcare cost, quality, practices
- Gastrointestinal disorders and treatments
- Dialysis and Renal Disease Management
Northwell Health
2017-2025
Long Island Jewish Medical Center
2015-2024
American College of Financial Services
2024
Hofstra University
2018-2024
North Shore University Hospital
2020-2024
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2020-2023
Lenox Hill Hospital
2022
Jewish Hospital
2020
Creative Commons
2020
Feinstein Institute for Medical Research
2020
Malnutrition is common among hospitalized patients in the United States, and its coded prevalence increasing. known to be associated with increased morbidity, mortality healthcare costs. Although national data indicate that number of malnutrition diagnoses hospital discharges has been steadily rising, an in‐depth examination demographic clinical characteristics these not conducted. We examined from 2010 Healthcare Cost Utilization Project (HCUP), most recent nationally‐representative...
Background : The Joint Commission has mandated universal screening and assessment of hospitalized patients for malnutrition since 1995. Although various validated nonvalidated tools are available, implementation this mandate not been well characterized. We report results a survey hospital‐based professionals in the United States describing their perspective on current range nutrition practices as associated gaps knowledge. Methods Materials Data from 2012–2013 cross‐sectional, web‐based...
Compared to elective surgery, emergent hernia repairs carry higher morbidity. Additionally, frailty is independently associated with worse postoperative outcomes. This study aimed assess if the surgical approach, minimally invasive surgery versus open, confers improved outcomes for frail patients who underwent repairs. The National Surgical Quality Improvement Program database (2018-2020) was queried emergency repair by Current Procedural Terminology (CPT) codes (49505-49659). A modified...
Intestinal ischemia-reperfusion (I/R) injury is a severe disease associated with high mortality. Stimulator of interferon genes (STING) an intracellular protein that activated by cytosolic DNA and implicated in I/R injury, resulting transcription type I interferons (IFN-α IFN-β) other proinflammatory molecules. Extracellular cold-inducible RNA-binding (eCIRP), damage-associated molecular pattern, induces STING activation. H151 small molecule inhibitor has not yet been studied as potential...
The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) is a professional society of physicians, nurses, dietitians, pharmacists, allied health professionals, researchers dedicated to assuring that every patient receives optimal nutrition care. A.S.P.E.N.'s mission improve care by advancing the science practice clinical metabolism. diversity our membership emphasizes both importance good in necessity team approach. These Standards Practice Support Physicians are an update 2003...
Abstract Background Sepsis is caused by the dysregulated immune response due to an initial infection and results in significant morbidity mortality humans. Extracellular cold inducible RNA binding protein (eCIRP) a novel mediator identified sepsis. We have previously discovered that microRNA 130b-3p inhibits eCIRP mediated inflammation. As mimics are very unstable vivo, we hypothesize engineered miRNA mimic named PS-OMe miR130, improves stability of protection from nuclease activity. further...
Enteral nutrition support is a critical component of modern burn care for severely burned patients. However, tube feeds are frequently withheld during the perioperative period because aspiration concerns. As result, patients requiring multiple operative procedures risk accumulating significant protein-calorie deficits. The objective this study was to describe our American Burn Association-certified center's experience implementing an intraoperative feeding protocol in defined as cutaneous...
Triggering receptor expressed on myeloid cells-1 (TREM-1) has important implications in sepsis and inflammation is a novel for extracellular cold-inducible RNA-binding protein (eCIRP). We hypothesize that the inhibition of TREM-1 via its interaction with eCIRP by peptide inhibitor M3 or knockout gene will attenuate injury associated severe hepatic ischemia/reperfusion (I/R).Wild-type (WT) C57BL/6 TREM-1-/- mice underwent 60 min 70% ischemia, 24 h reperfusion. Additionally, WT I/R were...
INTRODUCTION Extracellular cold-inducible RNA-binding protein (eCIRP) is a novel mediator of inflammation and tissue injury. It has been shown that miRNA 130b-3p acts as an endogenous inhibitor eCIRP. Because RNA mimics are unstable after in vivo administration, we have chemically engineered mimic (named PS-OMe miR130) to improve its stability by protection from nuclease activity. We hypothesize miR130 reduces eCIRP-mediated injury murine model hepatic ischemia/reperfusion (I/R), sterile...
Peripherally inserted central venous catheters (PICCs) are popular for a broad range of indications. As with other forms access, PICC use can be associated serious and potentially costly complications. In 2000, in response to the rising popularity use, surgeon-led team was created steward their placement. All requests were screened rigorously ensure rational use. Our hypothesis that creation dedicated would decrease inappropriate placement, overall complication rates, cost.The study...