A5014209815- Trauma and Emergency Care Studies
- Abdominal Trauma and Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Pelvic and Acetabular Injuries
- Hip and Femur Fractures
- Innovations in Medical Education
- Surgical Simulation and Training
- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Streptococcal Infections and Treatments
- Appendicitis Diagnosis and Management
- Hernia repair and management
- Urological Disorders and Treatments
- Sepsis Diagnosis and Treatment
- Diversity and Career in Medicine
- Abdominal Surgery and Complications
- Antibiotic Use and Resistance
- Trauma Management and Diagnosis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Antimicrobial Resistance in Staphylococcus
- Intestinal and Peritoneal Adhesions
- Congenital Anomalies and Fetal Surgery
- Dermatological and COVID-19 studies
- Hemodynamic Monitoring and Therapy
- Traumatic Brain Injury and Neurovascular Disturbances
Brigham and Women's Hospital
2016-2025
Harvard University
2016-2025
University of Puerto Rico at Carolina
2024
University of Tehran
2012-2024
National Institute for Health Research
2024
University of Birmingham
2024
Fundación Juan March
2023
Yale University
2023
American Association for the Surgery of Trauma
2015-2023
University of Nevada, Las Vegas
2022
The successful treatment of intraabdominal infection requires a combination anatomical source control and antibiotics. appropriate duration antimicrobial therapy remains unclear.We randomly assigned 518 patients with complicated adequate to receive antibiotics until 2 days after the resolution fever, leukocytosis, ileus, maximum 10 (control group), or fixed course (experimental group) for 4±1 calendar days. primary outcome was composite surgical-site infection, recurrent death within 30...
Emergency general surgery (EGS) carries a disproportionate burden of risk from medical errors, complications, and death compared with non-EGS (NEGS). Previous studies have been limited by patient procedure heterogeneity but suggest worse outcome in EGS patients because preoperative factors. The aim this study was to quantify the excess morbidity mortality associated controlling for patient-specific We hypothesized that is an independent factor mortality.We retrospectively analyzed data...
OBJECTIVE To evaluate the relationship between preoperative A1C and clinical outcomes in individuals with diabetes mellitus undergoing noncardiac surgery. RESEARCH DESIGN AND METHODS Data were obtained from National Surgical Quality Improvement Program database Research Patient Registry of Brigham Women’s Hospital. Patients admitted to hospital for ≥1 day after surgery 2005 2010 included study. RESULTS Of 1,775 patients diabetes, 622 (35%) had an value available within 3 months before After...
BACKGROUND The rarity of renal trauma limits its study and the strength evidence-based guidelines. Although management injuries has shifted toward a nonoperative approach, nephrectomy remains most common intervention for high-grade (HGRT). We aimed to describe contemporary HGRT in United States also evaluate clinical factors associated with after HGRT. METHODS From 2014 2017, data on (American Association Surgery Trauma grades III-V) were collected from 14 participating Level-1 centers. Data...
There is a scarcity of research on immunocompromised patients with necrotizing soft-tissue infection (NSTI).To evaluate the effect status in NSTI.Single-institution retrospective cohort study at tertiary academic teaching hospital affiliated major cancer center.Patients NSTI.Treatment Brigham and Women's Hospital Dana-Farber Cancer Institute between November 25, 1995, April 2011.Necrotizing infection-associated in-hospital mortality.Two hundred one were diagnosed as having NSTI. Forty-six...
ABSTRACTObjectives: Studies have shown that probiotics may decrease anxiety symptoms, but to our knowledge so far no trial has investigated the effects of in generalized disorder (GAD). The aim present study was determine as adjunctive therapy on severity and quality life (QOL) patients with GAD.Methods: Forty-eight drug-free a diagnosis GAD based DSM-V criteria were randomly assigned two groups receive daily either one capsule or placebo addition 25 mg sertraline for 8 weeks. Probiotic...
Recent reports have questioned the safety and efficacy of prehospital rapid sequence intubation (RSI) for patients with head trauma. The purpose this study is to determine rate successful RSI, associated complications, delays in transport critically injured trauma treated by a select, well-trained group paramedics frequent exposure procedure rigorous quality control system.A helicopter paramedic group's database patient flight records (1999 2003) was merged registry data suburban Level I...
Computed tomography (CT) has long been the gold standard in diagnosing patients with suspected small bowel obstruction (SBO). Recently, point-of-care ultrasound (POCUS) demonstrated comparable test characteristics to CT imaging for diagnosis of SBO. Our primary objective was estimate annual national cost saving impact a POCUS-first approach evaluation secondary objectives were reduction radiation exposure and emergency department (ED) length stay (LOS).We created ran 1000 trials Monte Carlo...
Resilience, or the ability to cope with difficulties, influences an individual's response life events including unexpected injury. We sought assess relationship between patient self-reported resilience traits and functional psychosocial outcomes 6 months after traumatic injury.Adult trauma patients 18 years 64 of age moderate severe injuries (Injury Severity Score, ≥9) admitted one three Level I centers 2015 2017 were contacted by phone at postinjury asked complete a validated Trauma Quality...
Prehospital procedures (PHP) by emergency medical services (EMS) are performed regularly in penetrating trauma patients despite previous studies demonstrating no benefit. We sought to examine the influence of PHPs on outcomes urban locations where transport center is not prolonged. hypothesized that without would have better than those undergoing PHP.This was an Eastern Association for Surgery Trauma-sponsored, multicenter, prospective, observational trial adults (18+ years) with torso...
Background: Recent studies have suggested the length of treatment intra-abdominal infections (IAIs) can be shortened without detrimental effects on patient outcomes. However, data from high-risk populations are lacking. We hypothesized that patients at high risk for failure will benefit a longer course antimicrobial therapy. Methods: Patients enrolled in Study to Optimize Peritoneal Infection Therapy (STOP-IT) trial were evaluated retrospectively identify factors associated with failure,...
Tourniquet use for extremity hemorrhage control has seen a recent increase in civilian usage. Previous retrospective studies demonstrated that tourniquets improve outcomes major trauma (MET). No prospective study been conducted to date. The objective of this was evaluate MET patients with prehospital tourniquet use. We hypothesized decreases the incidence arriving center shock.Data were collected prospectively adult at 26 Level I and 3 II centers from 2015 2020. Limbs applied setting...
Abstract MEN2A is a hereditary syndrome characterized by medullary thyroid carcinoma, hyperparathyroidism, and pheochromocytoma. Classically patients with pheochromocytoma initially present the triad of paroxysmal headaches, palpitations, diaphoresis accompanied marked hypertension. However, although reported as rare presentation, spontaneous hemorrhage within can an abdominal catastrophe. Unrecognized, this transformation rapidly result in death. We report only documented case thirty eight...