A5071737519- Burn Injury Management and Outcomes
- Trauma and Emergency Care Studies
- Injury Epidemiology and Prevention
- Wound Healing and Treatments
- Cardiac Arrest and Resuscitation
- Pediatric Pain Management Techniques
- Emergency and Acute Care Studies
- Sepsis Diagnosis and Treatment
- Abdominal Trauma and Injuries
- Family and Patient Care in Intensive Care Units
- Intensive Care Unit Cognitive Disorders
- Disaster Response and Management
- Immune Response and Inflammation
- Respiratory Support and Mechanisms
- Cell death mechanisms and regulation
- Traumatic Brain Injury and Neurovascular Disturbances
- Pressure Ulcer Prevention and Management
- Thermal Regulation in Medicine
- Neonatal Respiratory Health Research
- Urological Disorders and Treatments
- Nosocomial Infections in ICU
- Congenital Diaphragmatic Hernia Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Ureteral procedures and complications
- Pancreatitis Pathology and Treatment
Nationwide Children's Hospital
2016-2025
The Ohio State University
2015-2024
Children's Mercy Hospital
2017-2024
Narsee Monjee Institute of Management Studies
2024
Children's Hospital of Michigan
2019-2024
GTx (United States)
2020
Johns Hopkins Children's Center
2019
Johns Hopkins University
2019
Children's National
2019
Detroit Medical Center
2019
Abstract Introduction Following trauma and systemic inflammatory response syndrome (SIRS), the typical is an elevation of total complete blood count (CBC) a reduction lymphocyte count. This leukocytosis typically returns to normal within 48 hours. The persistence following associated with adverse outcomes. Although anergy dysfunction increased risk for infection sepsis, there paucity data regarding impact low in patients. Methods retrospective review prospectively collected from patients...
Background: Normal vital signs are typically associated with improved outcomes in trauma patients. Whether this association is true for geriatric patients unclear. Methods: A Level 1 center retrospective chart review of on presentation (heart rate [HR] and blood pressure) young (aged 17–35 years) 65 years or older) blunt victims from September 2003 to 2008 was preformed. Generalized nonlinear using piecewise regression the linear portion standard logistic models used model risk mortality as...
<h3>Importance</h3> It is unknown whether smartphone-based virtual reality (VR) games are effective in reducing pain among pediatric patients real-world burn clinics. <h3>Objective</h3> To evaluate the efficacy of a smartphone VR game on dressing with burns. <h3>Design, Setting, and Participants</h3> This randomized clinical trial included children aged 6 to 17 years who seen outpatient clinic large American Burn Association–verified center level I trauma between December 30, 2016, January...
Ethnic minorities and low income families tend to be in poorer health have worse outcomes for a spectrum of diseases. Health care provider bias has been reported potentially affect the distribution away from communities, minorities, patients with history substance abuse. Trauma is perceived as disease poor medically underserved. Minorities are overrepresented populations also less likely possess insurance leading potential overlapping effect. Traumatic brain injury (TBI) predominant cause...
Key features of virtual reality (VR) that impact the effectiveness pain reduction remain unknown. We hypothesized specific VR experience significantly VR’s in reducing during pediatric burn dressing care. Our randomized controlled trial included children 6 to 17 years (inclusive) who were treated outpatient clinic an American Burn Association–verified center. Participants randomly assigned (1:1:1) active (playing VR), passive (immersed same environment without interactions), or...
Abstract Background Virtual reality (VR) gaming is considered a safe and effective alternative to standard pain alleviation in the hospital. This study addressed potential effectiveness feasibility of VR game that was developed by our research team for repeated at-home burn dressing changes. Methods A randomized clinical trial conducted among patients recruited from outpatient clinic large American Burn Association–verified pediatric center between September 2019 June 2021. We included...
BACKGROUND Social Deprivation Index (SDI) is a composite measurement of disadvantage in which higher SDI indicates worse social deprivation. Previous studies have suggested relationship between pedestrian-vs-automobile (PVA) collisions and poverty among adults, but similar association using state-level pediatric data has not previously been shown. We hypothesize that PVA collision incidence will differ with urbanicity across Ohio. METHODS Coordinates for January 2012 through 2023 from Ohio’s...
There are no comprehensive management guidelines for pediatric blunt renal injury; therefore, we hypothesized that wide variation in care exists. We sought to describe contemporary of trauma and explore associations between clinical strategies adverse outcomes. retrospectively evaluated injury patients (younger than 18 years) treated at 11 level I centers from 2020 2022. categorized by the American Association Surgery Trauma grade (low, grades 1-3; high, 4-5) isolated versus polytrauma....
Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome in which signs and symptoms of heart (HF) occur despite normal left ventricular fraction. Transthoracic echocardiography (TTE) the first-line imaging modality but disparities patient pathways across UK can lead to delayed diagnosis treatment. We aimed develop validate consistent, clinically appropriate practical approach for reporting echocardiographic suspicion HFpEF. Using Delphi method, steering group...
Abstract Introduction Pediatric patients with severe burn injuries often require intensive care unit (ICU) admission. Comprehensive for these children requires a multidisciplinary treatment team, including physical therapy (PT) and occupational (OT), to support anti-deformity positioning, functional engagement, early mobilization (EM). Although EM is becoming the standard of in pediatric ICUs; it has not specifically been studied population, which may face unique barriers participation. This...
Abstract Introduction Burns are the fifth most common non-fatal pediatric injury worldwide, and commonly require therapeutic input to optimize outcomes. Rehabilitation interventions in adults with burns can decrease hospital length of stay improve outcomes, however similar evidence is lacking for burn patients. To delivery rehabilitation services, it first important accurately objectively capture dose occupational therapy (OT) physical (PT) interventions. Therefore, we aimed describe...
Abstract Introduction The Burn Care Quality Platform (BCQP) is a specialized data source designed to enhance tracking and management of burn patient within healthcare organizations. This platform provides structured approach collecting analyzing related injuries, interventions, outcomes. Our institutional goal was participate in the BCQP full become independent our previously used trauma registry also its overall ease use. Methods To support this transition, Data Coordinator position created...
Abstract Introduction Pediatric patients are at greater risk of developing shock during initial burn resuscitation than adult due to higher body-surface-area for size. Judicious use fluids is crucial decrease mortality and morbidity. To excessive crystalloid volume resuscitation, our center created a guideline in 2015 deemed difficult resuscitate, which replaces 1/3 the lactated ringer hourly infusion rate with 5% albumin. Methods We retrospectively reviewed admitted American Burn...
Abstract Introduction Pediatric thermal injury induces a heightened inflammatory response and immune dysfunction, which is associated with adverse clinical outcomes (e.g., infections). Specifically, burns ≥20% total body surface area or ≥5% full thickness in pediatric patients, results suppression are most at risk to develop subsequent infections. As such, immunomodulating therapeutics have been of great interest augment the following injury. Our hypothesis was that after reversible ex-vivo...
Abstract Introduction Multidisciplinary care and effective communication are essential to pediatric burn management. Inpatient multidisciplinary rounds a requirement for American Burn Association (ABA) verification, as they allow holistic address barriers recovery discharge. The ABA does not mandate such outpatient care. However, recognizing the equal importance of coordinating complex need cross-team communication, our center created weekly improve delivery. Methods A one-hour meeting was...
Programmed death 1 (PD-1) is an inhibitor protein receptor for the immune system and has been shown to be upregulated in animal models of critical illness as well after trauma burn victims humans. It believed that PD-1 may play a role dysfunction seen surgical illness. However, although prior studies have associated changes expression with altered cell function, it not known if correlation clinical status exists. We therefore aimed describe potential critically ill patients. This...
To determine the contribution of programmed death receptor (PD)-1 in morbidity and mortality associated with development indirect-acute lung injury. The immune cell interaction(s) leading to injury are not completely understood. In this respect, we have recently shown that murine surface coinhibitory receptor, PD-1, has a role septic morbidity/mortality is mediated part through effects on innate arm. However, it know if PD-1 how may be at cellular level. -/- mice were used model (hemorrhagic...
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Guidelines for nonoperative management (NOM) of high-grade pancreatic injuries in children have not been established, and wide practice variability exists. The purpose this study was to evaluate common clinical strategies across multiple pediatric trauma centers develop a consensus-based standard pathway.A multicenter, retrospective review conducted with (American Association Surgeons Trauma grade III-V) treated NOM between 2010 2015. Data were collected on demographics, management,...