A5063128717- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Appendicitis Diagnosis and Management
- Trauma and Emergency Care Studies
- Healthcare Policy and Management
- Abdominal Surgery and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Hernia repair and management
- Global Health Workforce Issues
- Diversity and Career in Medicine
- Intestinal Malrotation and Obstruction Disorders
- Congenital Anomalies and Fetal Surgery
- Venous Thromboembolism Diagnosis and Management
- Emergency and Acute Care Studies
- Clinical Nutrition and Gastroenterology
- Hospital Admissions and Outcomes
- Injury Epidemiology and Prevention
- Ultrasound in Clinical Applications
- Renal and Vascular Pathologies
- Esophageal and GI Pathology
- Neuroblastoma Research and Treatments
- Pectus Deformity Diagnosis and Treatment
- Urinary Bladder and Prostate Research
Children's Hospital of Wisconsin
2019-2025
Medical College of Wisconsin
2019-2025
Nationwide Children's Hospital
2022-2025
The Ohio State University
2022-2024
Riley Hospital for Children
2022
Cincinnati Children's Hospital Medical Center
2022
Kosair Children's Hospital
2022
The University of Texas Health Science Center at Houston
2022
Indiana University – Purdue University Indianapolis
2022
University of Louisville
2022
A report from a high-volume single center indicated survival benefit of receiving kidney transplant an HLA-incompatible live donor as compared with remaining on the waiting list, whether or not deceased was received. The generalizability that finding is unclear.
Within the GRADE (Grading of Recommendations Assessment, Development and Evaluation) framework, we performed a systematic review developed evidence-based recommendations to answer following PICO (Population, Intervention, Comparator, Outcomes) question: should patients who present pulseless after critical injuries (with without signs life penetrating thoracic, extrathoracic, or blunt injuries) undergo emergency department thoracotomy (EDT) (vs. resuscitation EDT) improve survival...
To investigate changes in pediatric kidney transplant outcomes over time and potential variations these between the early late posttransplant periods across subgroups based on recipient, donor, characteristics.Using multiple logistic regression multivariable Cox models, graft patient were analyzed 17,446 kidney-only transplants performed United States 1987 2012.Ten-year survival rates 90.5% 60.2%, respectively, after transplantation 2001, compared with 77.6% 46.8% 1987. Primary nonfunction...
Incompatible live donor kidney transplantation (ILDKT) offers a survival advantage over dialysis to patients with anti-HLA donor-specific antibody (DSA). Program-specific reports (PSRs) fail account for ILDKT, placing this practice at regulatory risk. We collected DSA data, categorized as positive Luminex, negative flow crossmatch (PLNF) (n = 185), flow, cytotoxic (PFNC) 536) or (PCC) 304), from 22 centers. tested associations between DSA, graft loss and mortality after adjusting PSR model...
To measure the implications of new Accreditation Council for Graduate Medical Education duty hour regulations education, well-being, and burnout.Longitudinal study.Eleven university-based general surgery residency programs from July 2011 to May 2012.Two hundred thirteen surgical interns.Perceptions impact hours on various aspects training, including 6 core competencies, were measured 3-point scales. Quality life, burnout, balance between personal professional career satisfaction using...
Background Incompatible live donor kidney transplantation is associated with an increased rate of antibody-mediated rejection (AMR) and subsequent transplant glomerulopathy. For patients severe, oliguric AMR, graft loss inevitable without timely intervention. Methods We reviewed our experience rescuing allografts this severe AMR phenotype by using splenectomy alone (n=14), eculizumab (n=5), or plus in addition to plasmapheresis. Results The study population was 267 consecutive donor-specific...
The risk of graft loss after pediatric kidney transplantation increases during late adolescence and early adulthood, but the extent to which this phenomenon affects all recipients is unknown. This study explored interactions between recipient factors high-risk age window, searching for a phenotype that may be less susceptible detrimental interval.With use Scientific Registry Transplant Recipients data from 1987 2010, across was quantified using multivariable piecewise-constant hazard rate...
IMPORTANCENo national standardized guidelines exist to date for venous thromboembolism (VTE) prophylaxis after pediatric trauma.While the risk of VTE trauma is generally lower children than adults, precise age at which increases not clear.OBJECTIVE To identify from low rate seen in toward higher adults.DESIGN, SETTING, AND PARTICIPANTS Multivariable logistic regression models were used estimate association between and odds when adjusting other factors.Participants included 402 329 patients...
The updated Banff classification allows for the diagnosis of antibody-mediated rejection (AMR) in absence peritubular capillary C4d staining. Our objective was to quantify allograft loss risk patients with consistently C4d-negative AMR (n = 51) compared C4d-positive 156) and matched control subjects without AMR. All first-year posttransplant biopsy results from January 2004 through June 2014 were reviewed correlated presence donor-specific antibody (DSA). not different on any baseline...
<h3>Objective</h3>To compare outcomes and costs of elective surgery for diverticular disease (DD) with those other diseases commonly requiring colectomy.<h3>Design</h3>Multivariable analyses using the Nationwide Inpatient Sample to across primary diagnosis while adjusting age, sex, race, year admission, comorbid disease.<h3>Setting</h3>A sample US hospital admissions from 2003-2009.<h3>Patients</h3>All adult patients (≥18 years) undergoing resection descending colon or subtotal colectomy who...
Identify risk factors for venous thromboembolism and develop assessment models pediatric trauma patients.
BACKGROUND AND OBJECTIVES Diagnosis of adnexal torsion is challenging due to variable clinical presentations and often inconclusive imaging results. We hypothesized that diagnostic delays are common, leading prolonged ischemia subsequent tissue loss. aimed identify factors associated with in pediatric patients torsion. METHODS performed a multi-institutional retrospective review females aged 5 18 years confirmed between 2013 2022. Delay care was defined as prior emergency department...
BACKGROUND Social Deprivation Index (SDI) is a composite measurement of disadvantage in which higher SDI indicates worse social deprivation. Previous studies have suggested relationship between pedestrian-vs-automobile (PVA) collisions and poverty among adults, but similar association using state-level pediatric data has not previously been shown. We hypothesize that PVA collision incidence will differ with urbanicity across Ohio. METHODS Coordinates for January 2012 through 2023 from Ohio’s...
To investigate the effect of providing personal clinical effectiveness performance feedback to general surgery residents regarding prescription appropriate venous thromboembolism (VTE) prophylaxis.Residents are frequently charged with prescribing medications for patients, including VTE prophylaxis, but rarely receive individual these practice habits.This prospective cohort study at Johns Hopkins Hospital compared outcomes across 3 periods: (1) baseline, (2) scorecard alone, and (3) plus...
Organ shortage has led to increased utilization of higher risk liver allografts. In kidneys, aggressive center-level use one type graft clustered with other types. this study, we explored behavior in utilization. We aggregated national transplant recipient data between 2005 and 2009 the center-level, assigning each center an aggressiveness score based on relative livers. Aggressive centers had significantly more patients reaching high MELDs (RR 2.19, 2.33 2.28 for number MELD > 20, 25 30, p...
Abstract Background Abdominal pain and other gastrointestinal symptoms are common presenting features of multisystem inflammatory syndrome in children (MIS-C) can overlap with infectious or abdominal conditions, making accurate diagnosis challenging. Case Presentation We describe the case a 16-year-old female who presented clinical suggestive appendicitis an computed tomography (CT) that revealed concerning for appendicitis. After laparoscopic appendectomy, histopathology appendix...