Yigit S. Guner

ORCID: 0000-0002-3748-0832
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About
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Research Areas
  • Congenital Diaphragmatic Hernia Studies
  • Neonatal Respiratory Health Research
  • Trauma and Emergency Care Studies
  • Infant Nutrition and Health
  • Congenital Heart Disease Studies
  • Emergency and Acute Care Studies
  • Esophageal and GI Pathology
  • Injury Epidemiology and Prevention
  • Mechanical Circulatory Support Devices
  • Cardiac Arrest and Resuscitation
  • Tracheal and airway disorders
  • Trauma Management and Diagnosis
  • Clinical Nutrition and Gastroenterology
  • Enterobacteriaceae and Cronobacter Research
  • Respiratory Support and Mechanisms
  • Pleural and Pulmonary Diseases
  • Breastfeeding Practices and Influences
  • Intestinal Malrotation and Obstruction Disorders
  • Congenital Anomalies and Fetal Surgery
  • Intraperitoneal and Appendiceal Malignancies
  • Appendicitis Diagnosis and Management
  • Pediatric Hepatobiliary Diseases and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Inflammatory mediators and NSAID effects
  • Gun Ownership and Violence Research

University of California, Irvine
2017-2025

University of California, Irvine Medical Center
2017-2025

Children's Hospital of Orange County
2017-2025

British Columbia Children's Hospital
2019-2023

Memorial Hermann
2023

Loma Linda University
2022

University of California, Riverside
2021

Children's Hospital of Los Angeles
2007-2018

Boston Children's Hospital
2017

University of California, Davis
2012

The purpose of this report is to describe the international growth, outcomes, complications, and technology used in pediatric extracorporeal life support (ECLS) from 2009 2015 as reported by participating centers Extracorporeal Life Support Organization (ELSO). To date, there are 59,969 children who have received ECLS ELSO Registry; among those, 21,907 since with an overall survival hospital discharge rate 61%. In 2009, 2,409 cases were performed at 157 centers. By 2015, that number grew...

10.1097/mat.0000000000000603 article EN ASAIO Journal 2017-05-27

Background Necrotising enterocolitis (NEC) is one of the most common and fatal intestinal disorders in preterm infants. Breast-fed infants are at lower risk for NEC than formula-fed infants, but protective components human milk have not been identified. In contrast to formula, contains high amounts complex glycans. Objective To test hypothesis that oligosaccharides (HMO) contribute protection from NEC. Methods Since intervention studies unfeasible due limited availability HMO, a neonatal rat...

10.1136/gutjnl-2011-301404 article EN Gut 2011-12-03

The management of infants with congenital diaphragmatic hernia (CDH) receiving extracorporeal life support (ECLS) is complex. Significant variability in both practice and prevalence ECLS use exists among centers, given the lack evidence to guide decisions. purpose this report review existing develop recommendations for CDH patients treated ECLS. This article was developed by Extracorporeal Life Support Organization interest group cooperation members Study Group Children’s Hospitals Neonatal...

10.1097/mat.0000000000001338 article EN ASAIO Journal 2021-01-28

Despite advancements in minimally invasive repair of pectus excavatum (MIRPE), Nuss procedure, postoperative pain control remains challenging. This report covers a multimodal regimen using bilateral single-shot paravertebral block (PVB) and thoracoscopic intercostal nerve (T3-T7) cryoablation, leading to significant reduction length stay (LOS) high rate same-day discharge.This is comparative study management protocols for patients undergoing the procedure at single center from 2016 through...

10.1007/s00383-023-05429-7 article EN cc-by Pediatric Surgery International 2023-03-26

Although enterocytes are capable of innate immune responses, the intestinal epithelium is normally tolerant to commensal bacteria. To elucidate mechanisms tolerance, we examined effect preexposure LPS on activation p38, c-Jun, and NF-kappaB in by several inflammatory stress stimuli. Shortly after initial challenge, become restimulation with or CpG DNA, but not IL-17 UV. The state which lasts 20-26 h, temporally coincides LPS-induced expression anti-inflammatory ubiquitin-editing enzyme A20....

10.4049/jimmunol.0803987 article EN The Journal of Immunology 2009-07-02

Background/Objective: Recent studies show the minimally invasive approach to repair of esophageal atresia (EA) and tracheoesophageal fistula (TEF) is feasible. This study aimed evaluate efficacy safety thoracoscopic versus open techniques. Methods: We performed a retrospective review EA/TEF cases from June 2000 July 2006. Patient characteristics, operative time, blood loss, duration narcotic usage, time extubation, first oral feeding, length stay, complications, follow-up were analyzed....

10.1089/lap.2007.0220 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2008-09-01

Electric bicycles (e-bikes) achieve higher speeds than pedal bicycles, but few studies have investigated the impact on injury rates specific to pediatric population. Utilizing National Electronic Injury Surveillance System (NEISS), we compared of for e-bikes, and gas-engine (mopeds) from 2011 2020.Descriptive bivariate inferential analyses were performed upon NEISS estimates e-bike, bicycle, moped injuries in children aged 2-18 years. Analyses stratified by patient age helmet usage. The...

10.1016/j.sopen.2023.06.004 article EN cc-by-nc-nd Surgery Open Science 2023-06-21
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