A5076329785- Nuclear physics research studies
- Advanced Chemical Physics Studies
- Atomic and Molecular Physics
- Quantum Chromodynamics and Particle Interactions
- Nuclear Physics and Applications
- Astronomical and nuclear sciences
- Particle accelerators and beam dynamics
- Atomic and Subatomic Physics Research
- Rare-earth and actinide compounds
- Radiopharmaceutical Chemistry and Applications
- Inorganic Fluorides and Related Compounds
- Clusterin in disease pathology
- Astrophysical Phenomena and Observations
- Cancer Research and Treatments
- Medical Imaging Techniques and Applications
- Peptidase Inhibition and Analysis
- Atmospheric Ozone and Climate
- X-ray Spectroscopy and Fluorescence Analysis
- High-pressure geophysics and materials
- Electron and X-Ray Spectroscopy Techniques
- Advanced biosensing and bioanalysis techniques
- Ureteral procedures and complications
- Nuclear Structure and Function
- Surgical site infection prevention
- Cell death mechanisms and regulation
Kobe University
1998-2025
Universidade de São Paulo
2009-2023
Universidade Cidade de São Paulo
2011-2023
Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud
2011
Universidade de Santo Amaro
2011
Vancouver General Hospital
2000
Okayama University
1990
We examined whether the serum matrix metalloproteinase-2 (MMP-2) level and MMP-2 density could be predictors of development extension prostate cancer. Serum samples were collected before any clinical treatment from 98 patients with cancer 76 benign prostatic hyperplasia (BPH). Control sera obtained 70 healthy men. The was determined by 1-step enzyme immunoassay. A newly defined parameter dividing volume, which measured ultrasonography. mean in significantly higher than control BPH groups....
Phosphorothioate (P=S) antisense oligonucleotides (ASO) targeting the cell survival gene clusterin synergistically enhance castration- and chemotherapy-induced apoptosis in prostate cancer xenografts. This study compares efficacy, tissue half-lives, toxicity of P=S ASO to third-generation backbone 2'-O-(2-methoxy)ethyl (2'MOE) ribose-modified ASO. Northern analysis quantified changes mRNA levels human PC-3 cells tumors. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay...
Although the 5-year relative survival rates for resectable solid tumors have improved over past few years, risk of postoperative recurrence necessitates effective monitoring strategies. Recent advancements in molecular residual disease (MRD) testing based on circulating tumor DNA (ctDNA) analysis shown considerable promise context predicting recurrence; however, significant barriers to widespread clinical implementation remain-mainly, low awareness among healthcare professionals, high costs,...
TPS883 Background: B440, an oral cancer therapeutic vaccine, is based on innovative vaccine platform utilizing gut microbiota ( B. longum; Bifidobacterium longum ) that can efficiently deliver the heterogeneous antigen protein to dendritic cells (DCs) in Peyer's patches gut-associated lymphoid tissue (GALT). B440 a lyophilized powder of inactivated 440, recombinant expressing partially modified human WT1 tumor-associated (amino acids 117-419 with single amino acid substitution at 236 from M...
Abstract Muscle-invasive bladder cancer (MIBC), a highly heterogeneous disease, shows genomic instability and high mutation rate, making it difficult to treat. Recent studies revealed that stem cells (CSCs) play critical role in MIBC frequent recurrence morbidity. Previous research has shown Cyclooxygenases-2 (COX-2) is particularly expressed cells. In recent years, the development of oncolytic adenoviruses their use clinical trials have gained increased attention. this study, we composed...
This study aimed to investigate the genomic features of small cell neuroendocrine prostate cancer (SCPC) in Japanese patients, assess their relationships with platinum-based chemotherapy efficacy, and evaluate potential treatment eligibility for therapies using profiling. retrospective included 21 patients diagnosed SCPC between 2018 2022. An expert pathologist reviewed biopsy specimens according World Health Organization classification. Biopsy samples from primary or metastatic lesions were...
[Background] The $\ensuremath{\alpha}$-cluster model was successful for describing spectroscopic properties of light nuclei near the shell closures. Evidences structure in $^{94}\mathrm{Mo}$ were shown, motivating search same other intermediate mass nuclei. [Purpose] systematic analysis and four even-even neighboring [Method] with local potential approach. [Results] A good general description experimental ground state bands is obtained only one variable parameter. It shown that employed...
Recent studies have shown the antiapoptotic activity of clusterin against a wide variety stimuli; however, functional role in Fas-mediated apoptosis has not been well characterized. We transfected cDNA into human renal-cell carcinoma (RCC) ACHN cells that scarcely express protein order to examine whether overexpression inhibits signal pathway for apoptotic cell death. No significant difference was observed vitro growth rates between clusterin-transfected line (ACHN/CL) and...
An analysis of the $\alpha$ + core properties $^{104}$Te along with a global discussion on $\alpha$-cluster structure above double-shell closures is presented from viewpoint local potential model. The interaction described by nuclear (1 Gaussian)$\times$(W.S. W.S.$^3$) shape two free parameters, which has been successfully tested in nuclei different mass regions. model produces $Q_{\alpha}$ values and $\alpha$-decay half-lives for agreement 2018 experimental data Auranen et al. energy range...
Background: Resonances around $x\ensuremath{\alpha}$ thresholds in light nuclei are recognized to be important basic aspects of nuclear structure. However, there is scarce experimental information associated with them.Purpose: We study the $\ensuremath{\alpha}$-clustering phenomenon resonant states $4\ensuremath{\alpha}$ threshold (14.44 MeV) ${}^{16}\text{O}$ nucleus.Method: The ${}^{12}\text{C}{(}^{6}\text{Li},d){}^{16}\mathrm{O}$ reaction was investigated an unprecedented resolution at a...
A systematic analysis of the $\alpha$ + core structure is performed in ground state bands even-even nuclei $22 \leq Z 42$ region terms Local Potential Model. The interaction described by nuclear potential (1 Gaussian)$\times$(W.S. W.S.$^3$) shape with 2 free parameters. Properties such as energy levels, reduced $\alpha$-widths, $B(E2)$ transition rates and rms charge radii are calculated compared experimental data. good agreement data obtained general, even for without {doubly closed shell...
Alpha resonant states in 13 C up to 15 MeV were excited by the 9 Be ( 6 Li , d ) reaction. The data taken at a bombarding energy of 25.5 employing São Paulo-Pelletron-Enge Split Pole facility and nuclear emulsion technique. resolution 50 keV allowed for separation contributions known 7/2 - (5/2 near + α threshold both associated with an L = 4 transfer. Several narrow alpha not previously measured detected, particular one 3α n populated 2 transfer, revealing 9Be component 1/2 cluster state...
The 9Be(6Li,d)13C reaction was used to investigate alpha resonant states in 13C up 15 MeV of excitation. measured at a bombarding energy 25.5 employing the São Paulo Pelletron‐Enge‐Spectrograph facility and nuclear emulsion detection technique. An resolution 50 keV obtained. Several narrow not previously were detected, particular one (3α+n) threshold populated by an L = 2 transfer, revealing 9Be+α component for 1/2− cluster state candidate this threshold. Experimental angular distributions...
The objective of this study was to characterize the involvement Fas receptor/ligand system in p53-dependent apoptosis human prostate cancer cells.The effects adenovirus-mediated p53 gene transfer (Ad5CMV-p53) into LNCaP, DU145, and PC3 cells on their growth, expression were examined by MTT assay, DNA fragmentation Northern blot analysis, respectively. sensitivity these an agonistic anti-Fas receptor antibody (CH11) antagonistic ligand (4H9) Ad5CMV-p53-induced analyzed assay assay.Ad5CMV-p53...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation M. R. D. Rodrigues, T. Borello‐Lewin, L. B. Horodynski‐Matsushigue, A. Cunsolo, F. Cappuzzello, J. Duarte, C. G. Ukita, Souza, H. Miyake; Alpha Resonances in 13C Excited by the 9Be (6Li,d) Reaction. AIP Conf. Proc. 21 May 2010; 1245 (1): 141–144. https://doi.org/10.1063/1.3448005 Download citation file: Ris...
The 94Mo nucleus is treated as an alpha-cluster interacting with inert core through a phenomenological local potential. properties of the ground state band alpha+90Zr system, such energy levels, intercluster rms radii and B(E2) transition strengths were calculated. These results are compared previous references available experimental data. Some predictions made concerning negative parity excited positive band.
Abstract The unstable nuclei 62 Ge and 64 are analyzed in terms of the α + core structure applying a nuclear potential with (1 Gaussian)×(W.S. W.S.3) shape. ground state bands first negative parity band calculated compared experimental data. gives good account energies from 0 to 8 state. rms intercluster separations B ( E 2) transition rates obtained for discussion is presented.
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation M. A. Souza, H. Miyake; for the alpha‐cluster structure in 90Sr 98Pd. AIP Conference Proceedings 10 August 2011; 1351 (1): 77–82. https://doi.org/10.1063/1.3608938 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Dropdown Menu input...
The halo nucleus ${}^{11}\mathrm{Li}$ is treated as a three-body system consisting of an inert core ${}^{9}\mathrm{Li}$ plus two valence neutrons. Faddeev equations are solved using separable potentials to describe the two-body interactions, corresponding in ${n\ensuremath{-}}^{9}\mathrm{Li}$ subsystem ${p}_{1/2}$ resonance virtual s-wave state. experimental energy taken input and transverse momentum distribution studied.
The main purpose of the present work is investigation α-cluster phenomenon in 16O. 12C(6Li,d)16O reaction was measured at a bombarding energy 25.5 MeV employing São Paulo Pelletron-Enge-Spectrograph facility and nuclear emulsion detection technique. Resonant states around 4α threshold were an resolution 15 keV allows to define previously unresolved. angular distributions absolute cross sections determined range 4-40 degree center mass system. upper limit for resonance widths obtained,...
The 9Be(6Li,d)13C and 12,13C(6Li,d)16,17O reactions were measured at the Sao Paulo Pelletron-Enge-Spectrograph facility 25.5 MeV incident energy. nuclear emulsion detection technique was applied. Several narrow resonances populated up to approximately 17 of excitation An excellent energy resolution obtained: 40 keV for 13C 15-30 16O. upper limit resonance widths determined. Recently, d-a angular correlations θd = 0° with 25 using LNS Tandem-MAGNEX Spectrometer facility.