- Pregnancy and Medication Impact
- Pharmacological Effects and Toxicity Studies
- Pharmaceutical studies and practices
- Hemoglobinopathies and Related Disorders
- Epilepsy research and treatment
- Iron Metabolism and Disorders
- Neonatal Health and Biochemistry
- Pharmaceutical Practices and Patient Outcomes
- Breastfeeding Practices and Influences
- Antibiotics Pharmacokinetics and Efficacy
- Drug-Induced Hepatotoxicity and Protection
- Poisoning and overdose treatments
- Effects and risks of endocrine disrupting chemicals
- Heavy Metal Exposure and Toxicity
- Child Nutrition and Feeding Issues
- Pregnancy and preeclampsia studies
- Maternal Mental Health During Pregnancy and Postpartum
- Metabolism and Genetic Disorders
- Cannabis and Cannabinoid Research
- Electrolyte and hormonal disorders
- Autism Spectrum Disorder Research
- Attention Deficit Hyperactivity Disorder
- Air Quality and Health Impacts
- Cytomegalovirus and herpesvirus research
- Neonatal Respiratory Health Research
Assaf Harofeh Medical Center
2016-2025
Tel Aviv University
2015-2024
Bridge University
2022
Ben-Gurion University of the Negev
2022
Hebrew University of Jerusalem
2018
Anna Needs Neuroblastoma Answers
2017
S.P.E.C.I.E.S.
2017
University of Florida
2014
Pediatrics and Genetics
1998-2002
Hospital for Sick Children
1993-1998
Human papillomavirus (HPV) infections cause anogenital cancers and warts. The 9-valent HPV vaccine provides protection against 7 high-risk types of responsible for 90% cervical 2 other accounting genital warts.To determine whether type-specific antibody responses would be noninferior among girls boys aged 9 to 14 years after receiving doses the compared with adolescent young women 16 26 3 doses.Open-label, noninferiority, immunogenicity trial conducted at 52 ambulatory care sites in 15...
Objective: Children with autism spectrum disorder (ASD) commonly exhibit comorbid symptoms such as aggression, hyperactivity and anxiety. Several studies are being conducted worldwide on cannabidiol use in ASD; however, these still ongoing, data the effects of its is very limited. In this study we aimed to report experience parents who administer, under supervision, oral cannabinoids their children ASD. Methods: After obtaining a license from Israeli Ministry Health, ASD were instructed by...
To determine whether the orally active iron chelator deferiprone (1,2-dimethyl-3-hydroxypyridin-4-one) is efficacious in treatment of overload patients with thalassemia major, we conducted a prospective trial 21 unable or unwilling to use standard chelation therapy parenteral deferoxamine.
Abstract BACKGROUND Azathioprine (AZP) interferes with nucleic acid synthesis and is teratogenic in animals. In view of the paucity information on use AZP during pregnancy we investigated this subject a prospective, controlled, multicenter study. Our objective was too determine whether exposure to increases risk for major malformations effect outcome. METHODS Pregnant women who contacted one seven teratogen services were compared cohort pregnant two took nonteratogenic treatments their...
In recent years there has been growing interest in the potential benefits of CBD-rich cannabis treatment for children with ASD. Several open label studies and one double-blind placebo-controlled study have reported that is safe potentially effective reducing disruptive behaviors improving social communication. However, previous mostly based their conclusions on parental reports without use standardized clinical assessments. Here, we conducted an to examine efficacy 6 months adolescents...
No AccessJournal of UrologyClinical Urology: Original Article1 Oct 1995Efficacy Prilocaine-Lidocaine Cream in Treatment Premature Ejaculation Matitiahu Berkovitch, Ara G. Keresteci, and Gideon Koren BerkovitchMatitiahu Berkovitch , KeresteciAra Keresteci KorenGideon View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66861-7AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluated...
Aim To investigate glutathione and antioxidant status changes in erythrocytes from febrile children receiving repeated supratherapeutic paracetamol doses. Methods Fifty‐one aged 2 months to 10 years participated the study. Three groups were studied: group 1 ( n = 24) included afebrile who did not receive paracetamol; 13) 3 14) had fever above 38.5°C for more than 72 h. Patients received at a dose of 50 ± 15 (30–75) mg kg −1 day those recommended therapeutic dose, ie 107 28 (80–180) . A blood...
The assessment of compliance is critical in the evaluation effectiveness a new therapeutic agent. Fifteen patients with transfusion‐dependent β‐thalassemia, many whom had previously demonstrated erratic deferoxamine, were enrolled clinical trial oral iron chelator, 1,2‐dimethyl‐3‐hydroxypyrid‐4‐one (L1). Their this medication was estimated by several existing methods and novel Medication Event Monitoring System (MEMS). Overall as assessed MEMS 78.5 ± 13.0% prescribed doses taken,...
What is already known about this subject • In general, use of herbal remedies and supplements constantly rising in the western population may be potentially dangerous due to adverse effects drug–herb interactions. All information up now has been derived from general or outpatients. There are no publications on rate consumption herbals inpatients, awareness medical team fact. study adds Approximately 25% patients hospitalized internal medicine wards consume some kind dietary supplement....
Numerous studies have suggested significant associations between prenatal exposure to heavy metals and newborn anthropometric measures. However, little is known about the effect of various metal mixtures at relatively low concentrations. Hence, this study aimed investigate exposures a wide range individual with measures newborns.We recruited 975 mother-term infant pairs from two major hospitals in Israel. Associations eight (arsenic, cadmium, chromium, mercury, nickel, lead, selenium,...
Patent ductus arteriosus (PDA), a common finding among premature infants, is conventionally treated by intravenous indomethacin. Intravenous ibuprofen was recently shown to be as effective and have fewer adverse reactions in preterm infants. If equally effective, then oral for PDA closure would several important advantages over the route. This study designed determine whether treatment efficacious safe of infants with respiratory distress syndrome.Twenty-two newborns (gestational age: 27.5...
Adverse drug reactions (ADRs) are associated with morbidity and mortality worldwide. Although national systems for reporting ADRs exist there is a low rate. The aim of the current study was to evaluate an intervention plan improving among medical professionals (physicians nurses). A multicentre conducted, in which one centre randomly assigned group two centres control group. consisted 3 phases: baseline data collection, follow-up questionnaire that filled at base line end study, contained...
In environmental epidemiology, we use systematic reviews to evaluate the evidence of exposure-outcome relationships with an eye towards regulation. Conflicting results across studies thwart consensus on toxicity. humans, only observational data is available from exposures, complicating construction dose-response full range exposure levels. Individual often lack complete levels because are tied study settings. Pooling populations seems a natural solution, but strong population-dependent...
The aim of this study is to determine the extent use medications that have not been specifically licensed for in children (unlicensed), or whose accordance with conditions their license (off-label), neonates a neonatal intensive care unit (NICU). Medications given 105 were prospectively reviewed every 2 weeks during 4-month period. assessment as whether medication prescribed was unlicensed off-label based on number reference sources. Five hundred and twenty-five series used, which 310 (59%)...
Nausea and vomiting are very common during pregnancy, mainly throughout the first trimester. Metoclopramide is a dopamine receptor blocking drug that commonly used to treat nausea vomiting. The aim of this prospective study was investigate effect on fetus intrauterine exposure metoclopramide. One hundred seventy-five women who received metoclopramide consulted 6 teratogen information centers in Israel, Italy, Brazil, Canada were studied. Women exposed paired for age, smoking alcohol...