A5101764603- Nanoplatforms for cancer theranostics
- Circular RNAs in diseases
- Microtubule and mitosis dynamics
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Atmospheric chemistry and aerosols
- MicroRNA in disease regulation
- Innovative Microfluidic and Catalytic Techniques Innovation
- Ubiquitin and proteasome pathways
- CRISPR and Genetic Engineering
- Microfluidic and Capillary Electrophoresis Applications
- Air Quality Monitoring and Forecasting
- Plant Reproductive Biology
- Atmospheric Ozone and Climate
- Immune cells in cancer
- Plant tissue culture and regeneration
- Plant responses to water stress
- Advanced Nanomaterials in Catalysis
- Biosensors and Analytical Detection
- S100 Proteins and Annexins
- Chromosomal and Genetic Variations
- Nanoparticle-Based Drug Delivery
- Genomics and Phylogenetic Studies
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
Shanghai University of Engineering Science
2024
Huashan Hospital
2011-2023
Xinyang College of Agriculture and Forestry
2023
Fudan University
2011-2023
North China University of Science and Technology
2022
Cangzhou Central Hospital
2021
Hebei Medical University
2021
China Medical University
2018-2020
Huazhong Agricultural University
2008
Abstract In this work, we developed a miniaturized palmtop high-speed capillary electrophoresis (CE) system integrating whole modules, including picoliter-scale sample injection, short capillary-based fast CE, high-voltage power supply, orthogonal laser induced fluorescence (LIF) detection, battery, control, on-line data acquisition, processing, storage, and display modules. A strategy of minimalist miniaturization combining minimal design low-cost construction was adopted to achieve the...
A-kinase anchor protein 12 (AKAP12; also known as Gravin) functions a tumor suppressor in several human primary cancers. However, the potential correlation between histone deacetylase 3 (HDAC3) and AKAP12 underlying mechanisms remain unclear. Thus, this study, an aim to shed light into matter, expression levels of HDAC3 96 colorectal cancer (CRC) adjacent non-cancerous tissues, well SW480 cells were examined by immunohistochemical, RT-qPCR western blot analyses. The effects on proliferation,...
Background AKAP12/Gravin (A kinase anchor protein 12) is one of the A-kinase scaffold proteins and a potential tumor suppressor gene in human primary cancers. Our recent study demonstrated highly recurrent loss AKAP12 colorectal cancer reexpression inhibited proliferation anchorage-independent growth cells, implicating pathogenesis. Methods To evaluate effect this on progression metastasis cancer, we examined impact overexpressing AKAP12-negative cell line LoVo, single clone (LoVo-AKAP12)...
Metastasis and recurrence are major causes of colorectal cancer (CRC) death, but their molecular mechanisms unclear. In this study, genes associated with CRC metastasis were identified by weighted gene coexpression network analysis, selecting the top 25% most variant in dataset GSE33113. By average linkage hierarchical clustering, a total 21 modules generated. One key module was as relevant to prognosis CRC. Gene Ontology analysis indicated that tumor significantly enriched inflammatory...
Restoring lost function to suppressor gene products has captured the interest of research community in field therapy. AKAP12, also known as Gravin/AKAP250, is a tumor gene, and its deregulation may be responsible for cancer progression. The aim this study was investigate whether AKAP12 mRNA an anti-cancer by regulating onco-miRNA expression colorectal (CRC) cells.miRNAs targeting were predicted bioinformatics analysis further confirmed dual-luciferase reporter assays RT-qPCR. altered...
microRNAs as novel tumor biomarkers exert important clinical value in early screening and antidiastole of human cancers. They show a broad prospect application, particularly due to their low invasive high sensitivity. This review focused on the application circulating microRNA for diagnosis monitoring treatment colorectal cancer based recent findings. Meanwhile, defects practice by using major causes which could constraint especially unreliable detection result caused many factors, have been...
Background: Entada phaseoloides (L.) Merr (Fabaceae) is a large woody climber that found widely in southern China and other tropical subtropical areas worldwide. The genus contains ~30 species, E. most commonly China. phaneroneura pervillei are endangered species. Previous studies had focused on medicinal components, transcriptional regulation, nuclear genomes. chloroplast genome of has not been reported, little known about the phylogenetic relationships within Entada. In this study, we...