A5050225057- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Psoriasis: Treatment and Pathogenesis
- Multiple Myeloma Research and Treatments
- Myasthenia Gravis and Thymoma
- Pituitary Gland Disorders and Treatments
- Soft tissue tumor case studies
- NF-κB Signaling Pathways
- Autoimmune and Inflammatory Disorders Research
- Hereditary Neurological Disorders
- Immune Response and Inflammation
- IL-33, ST2, and ILC Pathways
- Neurofibromatosis and Schwannoma Cases
- Glycosylation and Glycoproteins Research
- Sarcoma Diagnosis and Treatment
- Pediatric Urology and Nephrology Studies
- Hippo pathway signaling and YAP/TAZ
- Cell Adhesion Molecules Research
- Protein Hydrolysis and Bioactive Peptides
- Pelvic floor disorders treatments
- Animal Virus Infections Studies
- Systemic Lupus Erythematosus Research
- Urinary Tract Infections Management
- Influenza Virus Research Studies
- Oral and Maxillofacial Pathology
Chinese Academy of Medical Sciences & Peking Union Medical College
1997-2025
Guang’anmen Hospital
2023-2025
Peking Union Medical College Hospital
2014-2019
Institute of Hematology & Blood Diseases Hospital
2019
Affiliated Hospital of Southwest Medical University
2019
Academia Sinica
2000
To analyze the status and correlation factors of fatigue in patients with ankylosing spondylitis (AS), provide a reference for improving AS. Using AS-specific disease database Chinese Rheumatology Registration Research Information Platform, AS from 9 centers China were selected as study subjects March 2022 to September 2023. Functional Assessment Chronic Illness Therapy Scale (FACIT-F) score, activity score-C-reactive protein (ASDAS-CRP), score-erythrocyte sedimentation rate (ASDAS-ESR),...
Abstract Aim Ankylosing spondylitis (AS) is a chronic, progressive, and inflammatory autoimmune disease of unknown origin that affects the axial skeleton sacroiliac joints, resulting in pain loss function. AS characterized by overdifferentiation T helper 17 (Th17) cells, which contribute to development disease. The Hippo signaling pathway an important regulator Th17 differentiation, but its role patients with unclear. We aimed investigate key molecules differentiation examine their...
Ankylosing spondylitis (AS) is an autoimmune disease with complex inflammatory mechanism. The aim of this study to apply the methods bibliometrics and knowledge mapping analyze research trends hot spots B cells intervention in mechanism AS. Global published articles on B-cells AS were retrieved from Web Science (WOS) database 2004 2023. CiteSpace 6.1.R6 software was used conduct visualization analysis countries, authors, institutions, references keywords field. A total 359 related collected....
This study aimed to validate the mechanism of triptolide in treating ankylosing spondylitis (AS) through network pharmacology, molecular docking, and vitro experiments. We gathered AS-related genes using databases including DrugBank, OMIM, GeneCards, TTD DisGeNET. TCMSP database was used collect Tripterygium wilfordii (TWHF)-related data. Additionally, potential targets TWHF AS were predicted by consulting such as Venny, String, Cytoscape, Cytohubba. Subsequently, a protein-protein...
Background: Cytogenetic aberration detected by fluorescence in situ hybridization is one of the most important prognostic factors for multiple myeloma (MM). Identifying patients with high risk aberrations (HRA) critical initial stratification as well follow‐up treatment. Although specific HRA has been discussed, cumulative impact still unclear. Also, limited published reports on this issue were almost conducted context traditional chemotherapy, incomplete FISH detections. Aims: Based our...
Background: Multiple myeloma (MM) is a genetically complex and heterogeneous disease with multiple genomic events associated tumor development progression.Chromosomal translocations into the immunoglobulin heavy‐chain (IgH) locus on 14q32 are main primary events, occurring in about 50% of total MM cases. Currently, there five chromosomal translocation partners involving (IgH), including t(4;14), t(6;14), t(11;14), t(14;16) t(14;20). However, IgH undefined partner genes can still be found 15%...