A5100653355- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- Polymer Surface Interaction Studies
- Nanoparticle-Based Drug Delivery
- Advanced Nanomaterials in Catalysis
- Electrocatalysts for Energy Conversion
- Advanced Polymer Synthesis and Characterization
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Electrochemical sensors and biosensors
- Advanced battery technologies research
- RNA Interference and Gene Delivery
- Dendrimers and Hyperbranched Polymers
- Advanced Photocatalysis Techniques
- Hydrogels: synthesis, properties, applications
- Graphene and Nanomaterials Applications
- Antimicrobial agents and applications
- Polymer crystallization and properties
- Fuel Cells and Related Materials
- Antimicrobial Peptides and Activities
- Advanced Drug Delivery Systems
- Polymer Nanocomposites and Properties
- Wound Healing and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Covalent Organic Framework Applications
Central South University
2025
Sichuan University
2015-2024
Zigong First People's Hospital
2023-2024
Sichuan Research Center of New Materials
2023
Wuyi University
2019
Jiangmen Polytechnic
2019
Ingenierie des Materiaux polymeres
2011
Fudan University
2010
Institut des Biomolécules Max Mousseron
2008
Centre National de la Recherche Scientifique
2008
Nanomaterials-based artificial enzymes (AEs) have flourished for more than a decade. However, it is still challenging to further enhance their biocatalytic performances due the limited strategies tune electronic structures of active centers. Here, new path reported de novo design d electrons centers by modulating electron transfer in vanadium-based AEs (VOx -AE) via unique Zn-O-V bridge efficient reactive oxygen species (ROS)-catalysis. Benefiting from Zn V, V site VOx -AE exhibits lower...
Abstract Bioelectronics are powerful tools for monitoring and stimulating biological biochemical processes, with applications ranging from neural interface simulation to biosensing. The increasing demand bioelectronics has greatly promoted the development of new nanomaterials as detection platforms. Recently, owing their ultrathin structures excellent physicochemical properties, emerging two‐dimensional (2D) materials have become one most researched areas in fields biosensors. In this timely...
Injectable self-healing hydrogels containing functional nanoparticles (NPs) have attracted much attention in many fields of biomedicine. A series injectable PEGylation CuS NPs based on N-carboxyethyl chitosan (CEC) and oxidized sodium alginate (OA) were developed by taking advantages the unique functions chitosan, referred to as NP or CEC–OAm–CuSn, where "m" stands for concentration percentage added OA solution (w/v) "n" represents molar hydrogels. The physical properties hydrogels,...
Constructing highly effective biocatalysts with controllable coordination geometry for eliminating reactive oxygen species (ROS) to address the current bottlenecks in stem-cell-based therapeutics remains challenging. Herein, inspired by structure of manganese-based antioxidase, we report a manganese-coordinated polyphthalocyanine-based biocatalyst (Mn-PcBC) axial Mn-N5 sites and 2D d-π-conjugated networks that serves as an artificial antioxidase rescue stem cell fate. Owing unique chemical...
Abstract Among the platinum‐group metals, ruthenium (Ru), with a low water dissociation energy, is considered promising alternative to substitute Pt for catalyzing hydrogen evolution reaction (HER). However, optimizing adsorption–desorption energies of H * and OH intermediates on Ru catalytic sites extremely desirable but remains challenging. Inspired by natural characteristics Mn‐oxygen complex, this study reports design compounds coordinated (MOC‐Ru) deprotonated oxophilic...
Ruthenium (Ru)-based catalysts have displayed compelling hydrogen evolution activities, which hold the promising potential to substitute platinum in alkaline H2 -evolution. In challenging electrolytes, water-dissociation process involves multistep reactions, while profound origin and intrinsic factors of diverse Ru species on pathways reaction principles remain ambiguous. Here fundamental Ru-based media be from their unique electronic structures complex coordination environments are...
Abstract The past few decades have witnessed the flourish of creating metal oxides for biocatalytic therapeutics due to their structural diversities, feasible modifications, tunable catalytic sites, and low cost when compared natural enzyme counterparts. Here, in this timely review, most recent progress future trends engineering structured decoding structure‐reactivity relationships is comprehensively summarized. At first, fundamental activities, evaluations, mechanisms oxide‐based...
Abstract Metallophthalocyanines (MPcs) hold great promise in the electrochemical reduction of oxygen; however, their practical applications energy storage and conversion are still limited by low stability poor water oxidation activity. Herein, a novel stable 2D imide‐linked metalphthalocyanine framework (denoted as FePc‐PI) is reported, that has atomically dispersed Fe‐N 4 sites deposited on KB substrate via situ growth, followed incorporation ultrafine nickel oxide nanoparticles (NiO x...
Wound infection and tumor recurrence are the two main threats to cancer patients after surgery. Although researchers have developed new treatment systems address significant challenges simultaneously, potential side effects of heavy-metal-ion-based still severely limit their widespread application in therapy. In addition, wounds from removal compared with general operative more complex. The mainly exhibit hemorrhage, larger trauma area, greater vulnerability bacterial infection, residual...
Though numerous nanomaterials with enzyme-like activities have been utilized as probes and sensors for detecting biological molecules, it is still challenging to construct highly sensitive detectors biomarkers using polymeric materials. Benefiting from the π-d delocalization effect of electrons, excellent metal-chelating property, high electron transferability, good chemical stability π-conjugated phthalocyanine, design copper phthalocyanine-based conjugated polymer nanoparticles (Cu-PcCP...
Abstract Noble metal‐based electrocatalysts (NMECs), particularly those with active sites at the nano or atomic level, are indispensable in heterogeneous catalysis, which has attracted considerable research interests, especially energy communities. Due to enormous inherent merits, such as ultrahigh surface area, tunable structure, and diverse chemical tailorability, metal‐organic frameworks (MOFs) have been proposed ideal candidates for creating efficient programmable NMECs. In this review,...
Abstract Developing artificial enzymes based on organic molecules or polymers for reactive oxygen species (ROS)‐related catalysis has broad applicability. Herein, inspired by porphyrin‐based heme mimics, we report the synthesis of polyphthalocyanine‐based conjugated (Fe‐PPc‐AE) as a new porphyrin‐evolving structure to serve efficient and versatile augmented catalysis. Owing structural advantages, such enhanced π‐conjugation networks π‐electron delocalization, promoted electron transfer,...
TTB-COF with different crystallinities loaded Pt atoms were synthesized for HER. The Pt@TTB-COF higher crystallinity exhibited excellent performance low overpotential of 5 mV at 10 mA cm −2 and high TOF value 5.43 H 2 S −1 50 mV.
To alleviate the hemorrhagic side effect of thrombolysis therapy, a thrombus targeted drug delivery system based on specific affinity Annexin V to phosphatidylserine exposed membrane surface activated platelet was developed. The amphiphilic and biodegradable biomaterial, polycaprolactone-block-poly(2-(dimethylamino)ethyl methacrylate)-block-poly(2-hydroxyethyl methacrylate) (PCL-b-PDMAEMA-b-PHEMA (PCDH)) triblock polymer, synthesized via ring opening polymerization (ROP) atom transfer...
Exploring highly efficient, portable, and robust biocatalysts is a great challenge in colorimetric biosensors. To overcome the challenging states creating single-atom biocatalysts, such as insufficient activity stability, here, this work has engineered unique CeO2 support nanoglue to tightly anchor Ru sites (CeO2 -Ru) with strong electronic coupling for achieving sensitive H2 O2 -related biocatalytic diagnosis. The morphology chemical/electronic structure analysis demonstrates that atoms are...
<title>Abstract</title> Dual-atom catalysts (DACs) with synergetic dinuclear active sites, have the potential to break linear scaling relationship of well-established single-atom for oxygen reduction reaction (ORR); however, design DACs rationalized local microenvironment high activity and selectivity remains a blind area is great challenge. Herein, we reported bisalphen ladder polymer well-defined densely populated binuclear cobalt sites that in suit growth on Ketjenblack substrates...