Bo Yu

ORCID: 0000-0001-9587-7240
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About
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Research Areas
  • Heavy metals in environment
  • Radioactivity and Radon Measurements
  • Catalytic Cross-Coupling Reactions
  • Air Quality and Health Impacts
  • Advanced Graph Theory Research
  • Complexity and Algorithms in Graphs
  • Catalytic C–H Functionalization Methods
  • Water Quality and Pollution Assessment
  • Toxic Organic Pollutants Impact
  • Geochemistry and Geologic Mapping
  • Heavy Metal Exposure and Toxicity
  • Advanced Photocatalysis Techniques
  • Reliability and Maintenance Optimization
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Mesoporous Materials and Catalysis
  • Product Development and Customization
  • MXene and MAX Phase Materials
  • Graph Labeling and Dimension Problems
  • Advanced Multi-Objective Optimization Algorithms
  • Asymmetric Synthesis and Catalysis
  • 2D Materials and Applications
  • Statistical Methods and Inference
  • Technology Assessment and Management
  • Polyoxometalates: Synthesis and Applications
  • Catalytic Alkyne Reactions

Shaanxi Normal University
2014-2024

University of Wisconsin–Platteville
2024

Utah Valley University
2024

Deakin University
2020-2022

Wuhan University of Technology
2017-2022

Southeast University
2012-2021

Anhui University
2021

Novartis (China)
2020

Minzu University of China
2018-2019

Hangzhou Normal University
2017-2018

The study of yeast cell morphology requires consistent identification cycle phases based on bud size. A computer-based image processing algorithm is designed to automatically classify microscopic images cells in a microfluidic channel environment. were enhanced reduce background noise, and robust segmentation developed extract geometrical features including compactness, axis ratio, are then used for classification, the accuracy various machine-learning classifiers compared. linear support...

10.1117/1.3589100 article EN Journal of Biomedical Optics 2011-01-01

The study on metal(loid) contamination of sediment in river upstream is lacking. content, pollution, risk and source ten metal(loid)s (As, Co, Pb, Cu, Ni, Cr, V, Mn, Ba, Zn) the Danjiang River, China were investigated to explore environmental quality headwater area. pollution levels ascertained by geo-accumulation index, enrichment factor, load index ecological risks evaluated guidelines (SQGs) potential index. results indicated that mean contents determined except As exceeded their...

10.1016/j.ecolind.2021.107502 article EN cc-by-nc-nd Ecological Indicators 2021-02-21

The levels of potentially toxic metal(loid)s (PTMs) As, Cu, Co, Cr, Hg, Mn, Ni, Pb, and Zn in resuspended street dust (<100 μm particles) from a megacity north China were determined. sources PTMs analyzed using multivariate statistical analysis positive matrix factorization methods that combined the spatial distributions PTMs. Average Zn, Hg exceeded those found local soil samples, while Ni less than their background soil. overall contamination was characterized as moderately contaminated...

10.1016/j.envint.2021.107073 article EN cc-by-nc-nd Environment International 2022-01-05

To explore the true identity of palladium-catalyzed Sonogashira coupling reaction, montmorillonite (MMT)-supported transition metal nanoparticles (MMT@M, M = Pd, Cu, Fe, and Ni) were prepared, characterized, evaluated systematically. Among all MMT@M catalysts, MMT@Pd/Cu showed highest activity, it was successfully extended to 20 examples with 57%–97% yields. The morphology characterization revealed that crystalline bimetallic particles dispersed on a MMT layer as nanoalloy diameters ranged...

10.1021/am505798y article EN ACS Applied Materials & Interfaces 2014-10-15

A comprehensive study on concentration, spatial distribution, pollution, ecological–health risk and source of potentially toxic elements (PTEs) in dust residential area Xi'an, China were conducted to explore the environmental quality urban district. The results show that concentrations V, Ni, Mn less than, while contents Cr, Zn, Pb, Cu, Ba obviously larger soil background values Shaanxi. high–value PTEs primarily concentrated densely populated areas, heavily trafficked areas surroundings...

10.1016/j.ecoenv.2020.111679 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2020-11-21

With the rapid increase of protein sequences in post-genomic age, it is challenging to develop accurate and automated methods for reliably quickly predicting their subcellular localizations. Till now, many efforts have been tried, but most which used only a single algorithm. In this paper, we proposed an ensemble classifier KNN (k-nearest neighbor) SVM (support vector machine) algorithms predict localization eukaryotic proteins based on voting system. The overall prediction accuracies by...

10.1371/journal.pone.0031057 article EN cc-by PLoS ONE 2012-01-30

A neat palladium-catalyzed alkynylation reaction was developed with "super-active ester" as the carbonyl electrophile, which provides a clean and efficient synthetic protocol for broad array of ynone compounds under CO-, Cu-, ligand-, base-free conditions. The superior activity triazine ester rationalized by strong electron-withdrawing ability unique affinity on palladium. mechanistic experiment clearly demonstrated that N-Pd coordination plays crucial role highly C-O activation.

10.1021/acs.orglett.5b01466 article EN Organic Letters 2015-06-12

LCZ696 is a novel treatment for patients suffering from heart failure that combines the two active pharmaceutical ingredients sacubitril and valsartan in single chemical compound. While an established drug substance, new manufacturing process suitable large-scale commercial production had to be developed sacubitril. The use of chemocatalysis, biocatalysis, flow chemistry as state-of-the-art technologies allowed efficiently build up structure achieve defined performance targets.

10.1021/acs.joc.0c00473 article EN The Journal of Organic Chemistry 2020-05-15

During the early stage design of large-scale engineering systems, teams are challenged to balance a complex set considerations. The established structured approaches for optimizing system designs offer strategies achieving optimal solutions, but in practice suboptimal system-level results often reached due factors such as satisficing, ill-defined problems, or other project constraints. Twelve subsystem and practitioners at large aerospace organization were interviewed understand ways which...

10.1115/1.4031745 article EN Journal of Mechanical Design 2015-10-08

Abstract Enantioselective synthesis of chiral heterocyclic derivatives is an important and challenging topic in the field synthetic chemistry. In this work, first stereocontrolled dimerization‐type homo‐1,3‐dipolar [3+2] cycloaddition reaction glycine aldimino esters for creating new heterocycles bearing multiple stereogenic centers has been developed through phosphine ligand‐involved silver catalysis. A variety imidazolidines could be obtained with high yields good diastereoselectivities as...

10.1002/adsc.201700732 article EN Advanced Synthesis & Catalysis 2017-08-12

A highly diastereo- and enantioselective silver-catalyzed azomethine ylide–imine (AYI) cycloaddition reaction of glycine aldimino esters with imines was developed in which the Xing-Phos-controlled syn-selective or DTBM-Segphos-induced anti-selective AYI could be applied to synthesis a variety stereodivergent 1-alkyl-2,5-substituted imidazolidines high yields excellent enantioselectivities (up 99% ee) as well good diastereoselectivities 99:1 dr) under mild conditions.

10.1021/acs.orglett.8b00702 article EN Organic Letters 2018-04-17
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