- Musculoskeletal pain and rehabilitation
- Bacterial Infections and Vaccines
- Glioma Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Spine and Intervertebral Disc Pathology
- Pneumonia and Respiratory Infections
- Brain Metastases and Treatment
- Pain Management and Treatment
- Epilepsy research and treatment
- Cardiovascular Issues in Pregnancy
- CNS Lymphoma Diagnosis and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury and Neurovascular Disturbances
- Bioactive Compounds and Antitumor Agents
- Insects and Parasite Interactions
- Opioid Use Disorder Treatment
- Cardiac pacing and defibrillation studies
- Ion channel regulation and function
- Botulinum Toxin and Related Neurological Disorders
- Protein Kinase Regulation and GTPase Signaling
- Cardiovascular Syncope and Autonomic Disorders
- Herbal Medicine Research Studies
- Antibiotic Use and Resistance
- Ion Channels and Receptors
Duke Medical Center
2018-2021
Duke University Hospital
2018-2021
Duke University Health System
2020
Duke University
2019-2020
North Carolina School of Science and Mathematics
2019
To quantify health care resource utilization and risk of complications in painful diabetic peripheral neuropathy (pDPN).Adult patients diagnosed with diabetes mellitus or (DPN) were identified MarketScan from January 2010 to December 2015. Subgroups (pDPN nonpainful DPN) based on the use pain medications 6 months before a new indexed diagnosis 1 year thereafter. Health costs collected for up 5 years, charted those at least 2 years follow-up. Complication comparisons made using χ2 Fisher...
In Brief Study Design. Retrospective analysis of inpatient and outpatient medical insurance claims data from a database containing >100 million individuals. Objective. The aim this study was to quantify the health care resource utilization (HCRU) nonsurgical treatments in first 2 years after chronic, refractory low back pain (CRLBP) diagnosis. Summary Background Data. Patients with persistent (LBP) despite conventional management who are not candidates for spine surgery considered have CRLBP...
Atrial fibrillation (AF) is a leading arrhythmia worldwide, and autonomic nervous system (ANS) dysfunction pivotal in its pathogenesis. This review synthesizes mechanistic insights into how sympathetic parasympathetic dysregulation modulates atrial electrophysiology, highlighting emerging therapies targeting neural pathways. We critically appraise pharmacologic, catheter-based, neuromodulatory approaches, including beta-blockers, low-level vagus nerve stimulation (LL-VNS), renal denervation...
Abstract BACKGROUND Opioid misuse in the USA is an epidemic. Utilization of neuromodulation for refractory chronic pain may reduce opioid-related morbidity and mortality, associated economic costs. OBJECTIVE To assess impact spinal cord stimulation (SCS) on opioid dose reduction. METHODS The IBM MarketScan® database was retrospectively queried all US patients with a diagnosis undergoing SCS between 2010 2015. usage before after procedure quantified as morphine milligram equivalents (MME)....
Introduction. Previous studies of viral encephalitis have focused on acute costs, estimating incidence at 7.3 per 100 000 and total US annual charges $2 billion in 2010. Aim. We aim to quantify the most updated longitudinal health economic impact USA from 2008 2015. Methodology. Data patients diagnosed with were obtained Truven Health Analytics MarketScan database. Patients a primary diagnosis encephalitis, herpetic viruses other aetiologies (e.g. West Nile fever) included analysis....
Introduction. Paediatric bacterial meningitis remains a costly disease, both financially and clinically. Hypothesis/Gap Statement . Previous epidemiological cost studies of (BM) have largely focused on adult populations or single pathogens. There been few recent, large-scale pediatric BM in the USA. Aim. We examined healthcare resource utilization (HCRU) associated morbidity mortality community-acquired versus nosocomial infections children across Methodology. The IBM MarketScan Research...
To examine the longitudinal health care resource utilization, in-hospital mortality, and incidence of downstream complications bacterial meningitis in United States.
The economic burden of cancer in the United States is substantial, and better understanding it essential informing health care policy innovation. Leptomeningeal carcinomatosis (LC) represents a late complication primary spreading to leptomeninges.The IBM MarketScan Research databases were queried for adults diagnosed with LC from 2001 2015, secondary 4 cancers (breast, lung, gastrointestinal, melanoma). Health resource utilization (HCRU) treatment quantified at baseline (1-year pre-LC...
Adil, Syed M BS; Charalambous, Lefko T Spears, Charis A BA; Kiyani, Musa MD; Hodges, Sarah E Yang, Zidanyue MB; Lee, Hui-Jie PhD; Rahimpour, Shervin Parente, Beth PA-C; Greene, Kathryn MPP; McClellan, Mark MD, Lad, Shivanand P PhD
INTRODUCTION: The economic burden of low back pain (LBP) in the US is estimated between $84.1 and $624.8 billion. Some patients with LBP that persists despite conventional medical management are ineligible for spine surgery considered to have non-surgical refractory (NSRBP). We investigated healthcare resource utilization (HCRU) NSRBP. METHODS: IBM MarketScan® Research databases were queried adult a diagnosis LBP, excluding instability (eg, spondylolisthesis) non-mechanical etiologies,...
INTRODUCTION: Low back pain (LBP) is the leading cause of disability worldwide. Patients with persistent LBP despite multiple interventions and who are ineligible for spine surgery considered to have nonsurgical refractory (NSRBP). We investigated utilization medications nonpharmacologic therapies in this population United States. METHODS: The IBM MarketScan® Research databases were used identify adult patients diagnoses (excluding instability nonmechanical etiologies) a negative history...
Abstract INTRODUCTION Leptomeningeal carcinomatosis (LC) represents a late complication of primary cancer spreading to the leptomeninges. METHODS The IBM MarketScan® Research databases were queried for adult patients diagnosed with LC between 2001 and 2015, secondary four solid tumors (breast, lung, gastrointestinal, melanoma). outcome was overall healthcare resource utilization (HCRU) each subgroup, quantified as total cost at baseline (1-year pre-LC diagnosis) 30, 90, 365 days post-LC...
May 9, 2019April 2019Free AccessPrevalence and Healthcare Resource Utilization of Community-acquired Nosocomial Bacterial Meningitis Infections in the United States (S45.004)Sarah E. Hodges, Musa Kiyani, Syed M. Adil, Lefko T. Charalambous, Promila Pagadala, Beth Parente, Hui-Jie Lee, Beiyu Liu, Christopher Eckstein, Shivanand Pramod LadAuthors Info & AffiliationsApril 2019 issue92 (15_supplement)https://doi.org/10.1212/WNL.92.15_supplement.S45.004 Letters to Editor
May 6, 2019April 9, 2019Free AccessTreatment Comparison of Critically Ill Patients with Non-Convulsive Seizures or Status Epilepticus Receiving Levetiracetam Prophylaxis (P2.9-077)Safa Kaleem, Rana Moosavi, Musa Kiyani, and Christa SwisherAuthors Info & AffiliationsApril 2019 issue92 (15_supplement)https://doi.org/10.1212/WNL.92.15_supplement.P2.9-077 Letters to the Editor