A5006490281- Musculoskeletal pain and rehabilitation
- Glioma Diagnosis and Treatment
- Sleep and related disorders
- Sleep and Wakefulness Research
- Pain Management and Treatment
- Cerebrospinal fluid and hydrocephalus
- Neurosurgical Procedures and Complications
- Bacterial Infections and Vaccines
- Sleep and Work-Related Fatigue
- Brain Metastases and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Pneumonia and Respiratory Infections
- Opioid Use Disorder Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Health Systems, Economic Evaluations, Quality of Life
- Spine and Intervertebral Disc Pathology
- Meningioma and schwannoma management
- Fetal and Pediatric Neurological Disorders
- Cardiac Health and Mental Health
- Renal Diseases and Glomerulopathies
- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Infectious Encephalopathies and Encephalitis
- Renal cell carcinoma treatment
- Antibiotic Use and Resistance
Duke Medical Center
2019-2024
Duke University Hospital
2020-2024
Yale University
2016-2023
Bridge University
2021
University of Puerto Rico at Carolina
2021
Duke University
2020
North Carolina School of Science and Mathematics
2019
Connecticut Mental Health Center
2016
In Brief Study Design. Retrospective analysis of inpatient and outpatient medical insurance claims data from a database containing >100 million individuals. Objective. The aim this study was to quantify the health care resource utilization (HCRU) nonsurgical treatments in first 2 years after chronic, refractory low back pain (CRLBP) diagnosis. Summary Background Data. Patients with persistent (LBP) despite conventional management who are not candidates for spine surgery considered have CRLBP...
Abstract BACKGROUND Opioid misuse in the USA is an epidemic. Utilization of neuromodulation for refractory chronic pain may reduce opioid-related morbidity and mortality, associated economic costs. OBJECTIVE To assess impact spinal cord stimulation (SCS) on opioid dose reduction. METHODS The IBM MarketScan® database was retrospectively queried all US patients with a diagnosis undergoing SCS between 2010 2015. usage before after procedure quantified as morphine milligram equivalents (MME)....
Study Objectives: Insomnia, though quite common in the general population, is especially prevalent among individuals with co-occurring mental illnesses, patients whose condition can be further exacerbated by insomnia and vice versa.For taking one or more psychotropic medications, cognitive behavioral therapy for (CBT-I), gold standard treatment, a particularly favorable option (vis-à-vis pharmacotherapy).However, CBT-I inaccessible persons low socioeconomic status, group that includes many...
During abstinence, chronic cocaine users experience an objective worsening of sleep that is perceived as qualitatively improving. This phenomenon has been termed "occult insomnia." The this study was to determine whether positive state misperception during abstinence. Forty-three cocaine-dependent persons were admitted inpatient research facility for 12 days and 11 nights participate in a treatment modafinil. Polysomnographic recordings performed on 3, 4, 10, 11, when participants average 1...
Introduction. Previous studies of viral encephalitis have focused on acute costs, estimating incidence at 7.3 per 100 000 and total US annual charges $2 billion in 2010. Aim. We aim to quantify the most updated longitudinal health economic impact USA from 2008 2015. Methodology. Data patients diagnosed with were obtained Truven Health Analytics MarketScan database. Patients a primary diagnosis encephalitis, herpetic viruses other aetiologies (e.g. West Nile fever) included analysis....
Nontraumatic, primary intracerebral hemorrhage (ICH) accounts for 2 million strokes worldwide annually and has a 1-year survival rate of 50%. Recent studies examining functional outcomes from ICH evacuation have been performed, but limited work done quantifying the incidence subsequent complications their healthcare economic impact. The purpose this study was to quantify resource utilization (HCRU) major that can arise ICH.
Introduction. Paediatric bacterial meningitis remains a costly disease, both financially and clinically. Hypothesis/Gap Statement . Previous epidemiological cost studies of (BM) have largely focused on adult populations or single pathogens. There been few recent, large-scale pediatric BM in the USA. Aim. We examined healthcare resource utilization (HCRU) associated morbidity mortality community-acquired versus nosocomial infections children across Methodology. The IBM MarketScan Research...
Traumatic spinal cord injury (SCI) is a serious public health problem. Outcomes are determined by severity of immediate injury, mitigation secondary downstream effects, and rehabilitation. This study aimed to understand how the center type patient presents whether they transferred influence management outcome.
Leptomeningeal metastases (LM), late-stage cancer when malignant cells migrate to the subarachnoid space (SAS), have an extremely poor prognosis. Current treatment regimens fall short in effectively reducing SAS tumor burden. Neurapheresis therapy is a novel approach employing filtration and enhanced circulation of cerebrospinal fluid (CSF). Here, we examine vitro use neurapheresis as novel, adjunctive option for LM by filtering augmenting distribution drugs that may potential enhance...
Postoperative hydrocephalus occurs in one-third of children after posterior fossa tumor resection. Although models to predict the need for CSF diversion resection exist preoperative variables, it is unknown which postoperative variables diversion. In this study, authors sought determine clinical and radiographic predictors following
To examine the longitudinal health care resource utilization, in-hospital mortality, and incidence of downstream complications bacterial meningitis in United States.
The economic burden of cancer in the United States is substantial, and better understanding it essential informing health care policy innovation. Leptomeningeal carcinomatosis (LC) represents a late complication primary spreading to leptomeninges.The IBM MarketScan Research databases were queried for adults diagnosed with LC from 2001 2015, secondary 4 cancers (breast, lung, gastrointestinal, melanoma). Health resource utilization (HCRU) treatment quantified at baseline (1-year pre-LC...
Adil, Syed M BS; Charalambous, Lefko T Spears, Charis A BA; Kiyani, Musa MD; Hodges, Sarah E Yang, Zidanyue MB; Lee, Hui-Jie PhD; Rahimpour, Shervin Parente, Beth PA-C; Greene, Kathryn MPP; McClellan, Mark MD, Lad, Shivanand P PhD
BACKGROUND AND IMPORTANCE: Acute subdural hematoma (aSDH) is one of the most common pathologies resulting from head trauma. Surgical management often involves a large craniotomy for evacuation. Prior complex cranial reconstructive surgery can complicate incision planning or limit size. CLINICAL PRESENTATION: In this report, we describe 61-year-old woman with history squamous cell carcinoma scalp, which previously required flap reconstruction and left residual skull defect, who presented an...
INTRODUCTION: Intracerebral hemorrhage (ICH) is a major cause of morbidity and mortality worldwide, with 1-mo rate between 30% 50%. Our goal was to quantify additional healthcare resource utilization (HCRU) incurred by the US health system due complications sustained during initial ICH hospital admissions, including cost comparison treated invasively vs noninvasively. METHODS: The IBM MarketScan databases were used retrospectively identify patients prevalence HCRU associated complications....
INTRODUCTION: Various new waveforms for spinal cord stimulation (SCS) have emerged in recent years, with limited data supporting their utility a real-world clinical setting. We report results of protocolized workflow algorithm that allows high dose (HD) and low (LD) neurostimulation patients chronic pain undergoing SCS trial or permanent procedures. METHODS: Prospective was collected using the ManageMySurgery (MMS) mobile device platform Medtronic implant E-consent obtained through HIPAA...
INTRODUCTION: Pediatric patients with epilepsy often undergo language mapping using electrical cortical stimulation. Previous studies have shown general localization of auditory naming in the anterior temporal lobe and visual posterior parietal lobe. No probabilistic map exists, however, that quantifiably details location different modalities for pediatric epilepsy. METHODS: A series 41 consecutive underwent (24 female; range 5.2-18.5 yr; mean age 13.8 yr), either extraoperative (n = 34) or...