Recent studies have shown promising results in using Deep Learning to detect malignancy whole slide imaging, however, they were limited just predicting a positive or negative finding for specific neoplasm. We attempted use with convolutional neural network (CNN) algorithm build lymphoma diagnostic model four categories: (1) benign lymph node, (2) diffuse large B-cell lymphoma, (3) Burkitt and (4) small lymphocytic lymphoma. Our software was written Python language. obtained digital...

Nodular hidradenoma is an uncommon cutaneous adnexal tumor arising from sweat glands. In the skin, it usually presents as a solitary dermal nodule; excision curative in most cases. rare instances, may present breast mass and can mimic carcinoma clinically radiologically, causing diagnostic dilemmas for treating physician pathologist. Herein, we discuss case of nodular 20-year-old Hispanic woman rapidly growing that mimicked carcinoma. We presentation this differential diagnosis entity, well...

Over the past decade, dermatological practice has seen an increase in number of patients suffering from skin and subcutaneous tissue diseases. Annually, 6.4-6.9 million new cases this group diseases are registered, which encourages constant search for drugs continuous improvement methods schemes application proven drugs. Topical corticosteroids, despite more than 65 years history use treatment with steroid-sensitive dermatoses, have not lost their relevance. At present, they no therapeutic...

We report a case of premature newborn girl with hospital course complicated by suspected respiratory syncytial virus pneumonitis for which she was placed on veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Despite phototherapy, her total bilirubin steadily increased to peak 50.4 mg/dL concern bilirubin-induced neurologic dysfunction, kernicterus.Therapeutic plasma exchange (TPE) achieved via connection the VA-ECMO circuit. Our institution's standard apheresis procedural...

Current data on the acne pathogenesis are given. According to authors, dermatosis is becoming more prevalent among women of mature age. Issues related clinical picture, effect exogenous and endogenous factors course acne, psychosocial characteristics delayed manifestations in described detail. The essential role medical cosmetic products for complex therapy discussed. authors describe their own experience treating using Hyseac line a combination with microdermabrasion no-needle mesotherapy...

The article presents the results of a clinical observation rare dermatosis, pyoderma gangrenosum, and successful complex treatment disease with systemic GCS, azathioprine, antibiotics phototherapy using «PhotoDyn-750» device.

There has been an increase in the number of dermatology patients suffering from several concomitant skin diseases different etiology for past decade. A special term - dermatoses mixed (DME) was suggested to describe this group diseases. According authors, long-term uninterrupted treatment with one-component topical drugs or unreasonable administration three-component combination agents is most frequent reason DME. The authors their positive experience administering Travocort as a part DME...

The management of primary immune thrombocytopenia (ITP) is becoming a subject interest as there appears to be treatment failure and resistance modern conventional treatment, necessitating more universal goal-directed approach management. Our patient 74-year-old male who was diagnosed with ITP six years ago recently presented the emergency department (ED) complaints melena stools severe fatigue lasting for two days. Prior ED presentation, he had received multiple lines including splenectomy....

Provides the modern data about barrier features of skin and structures, providing such features. Key pathologic mechanisms, serving basis for diseases, are being considered. Data on external endogenous factors, causing breach, as well clinical xerosis is given. Recommendations basic care dry xerotic skin, using Xemoz cosmeceuticals, independent therapy, combined with other pharmaceuticals, highlighted.

The authors present current data about the epidemiology, clinical picture and principles of diagnostics treatment late-onset acne in women. emphasize leading part endocrine hormonal disorders hyperandrogenism women with late acne. They provide recommendations for basic skin care onset at a mature age using medical cosmetic products Matidiane line. share their observations concerning efficacy products.

The authors provide a review of current concepts the epidemiology, etiology, pathogenesis and treatment principles for seborrheic scalp dermatitis. They also describe results multiple national foreign studies confirming high clinical efficacy ketoconazole 2% shampoo in therapy

A premature baby girl with a complicated hospital course developed RSV pneumonitis at 2 months of age for which she was placed on extracorporeal membrane oxygenation (ECMO). In spite earlier phototherapy, bilirubin steadily increasing and reached 50.4 mg/dL concern induced neurologic dysfunction. Exchange transfusion not recommended due to patient instability risk significant deterioration while ECMO. Plasma exchange (PLEX), although recognized as category treatment option hyperbilirubinemia...

Toxic epidermal necrolysis (TEN) has been long believed to be the most severe manifestation of drug allergy. However, cutaneous changes as TEN in systemic lupus erythematosus (SLE) were first described late 1970s. As now, English-language literature published reports 30 cases such lesions SLE. This paper describes a clinical case direct SLE; positive experience depicted using not only intravenous immunoglobulin, but also rituximab with good therapeutic effect Russian practice.

Primary retroperitoneal mucinous cystic neoplasm (PRMCN) is extremely rare, and its etiology, pathogenesis, prognosis remain unclear with histology being similar to ovarian or pancreatic counterparts. We herein report an unusual case of PRMCN malignant transformation leading multifocal invasive adenocarcinoma in the small large bowel from our institution. The patient was a 23-year-old overweight woman presenting fever, nausea, vomiting, abdominal pain, 17 cm lesion right mid abdomen which...

Представлены современные научные данные об эпидемиологии и клинических проявлениях папилломавирусной инфекции кожи. Приведен обзор методов физической химической деструкции, которые применяют в современной клинической практике для лечения бородавок. Акцентировано внимание на методе деструкции с использованием аппликации препаратов салициловой кислотой, как наиболее эффективном, безопасном доступном способе терапии Приведены литературы собственных исследований по эффективности безопасности...

In the article data of microbiological monitoring peritoneal effusion during postoperative period in patients with colorectal cancer is presented. Rationale for performing crops exudate was demonstrated all groups and antibacterial therapy should be corrected on its base.

The goal of the study. Evaluating effectiveness treatment men with a diagnosis «Seborrheic dermatitis scalp» by system using retinol palmitate. Material and methods. 36 patients every day for 2 months received overnight per os 200000 ME palmitate, in comparison group (39 people) antiseborrheic shampoos have been used. dynamics severity skin oiliness, pruritis, erythema, peeling, infiltration, excoriations has evaluated points. Before after histological morphometric study biopsy material from...

The goal of the study. Evaluating effectiveness treatment men with a diagnosis «Seborrheic dermatitis scalp» by system using retinol palmitate. Material and methods. 36 patients every day for 2 months received overnight per os 200000 ME palmitate, in comparison group (39 people) antiseborrheic shampoos have been used. dynamics severity skin oiliness, pruritis, erythema, peeling, infiltration, excoriations has evaluated points. Before after histological morphometric study biopsy material from...

Side effects of chemotherapy in cancer patients treated by fotemustin are described, manifesting the hand-foot syndrome - ulcerative necrotic polymorphic dermal angiitis.