A5082861646- Protein Degradation and Inhibitors
- Histone Deacetylase Inhibitors Research
- Blood groups and transfusion
- Chromatin Remodeling and Cancer
- Cancer and Skin Lesions
- Ubiquitin and proteasome pathways
- Breast Lesions and Carcinomas
- Salivary Gland Tumors Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Hemoglobinopathies and Related Disorders
- Platelet Disorders and Treatments
- Erythrocyte Function and Pathophysiology
- Lymphoma Diagnosis and Treatment
- Blood donation and transfusion practices
- Tumors and Oncological Cases
- Head and Neck Surgical Oncology
- Hepatitis B Virus Studies
- Ear and Head Tumors
- Oral and Maxillofacial Pathology
- Blood disorders and treatments
- Chronic Lymphocytic Leukemia Research
- Soft tissue tumor case studies
- Metastasis and carcinoma case studies
- Sarcoma Diagnosis and Treatment
- Viral-associated cancers and disorders
The University of Texas Southwestern Medical Center
2015-2024
The University of Texas Health Science Center at Houston
2017-2024
Southwestern Medical Center
2015-2024
The University of Texas MD Anderson Cancer Center
2016-2017
NorthShore University HealthSystem
2014-2015
Evanston Hospital
2012-2015
University of Chicago
2015
Southwestern University
2015
Post Graduate Institute of Medical Education and Research
2004-2013
Harvard University Press
1997
Progressive and inexorable beta-cell dysfunction is the hallmark of type 2 diabetes mellitus (T2DM) regeneration using stem cell therapy may prove to be an effective modality. A total 10 patients (8 men) with T2DM for >5 years, failure triple oral antidiabetic drugs, currently on insulin (> or = 0.7 U/kg/day) at least 1 year, glutamic acid decarboxylase antibody negative were included. Patients stable doses medications past 3 months recruited. Primary end points reduction in requirement by >...
Red blood cell (RBC) alloimmunization results from genetic disparity of RBC antigens between donor and recipients. There is a paucity data on the incidence in transfused recipients region studied, as pre-transfusion antibody screening not routinely performed.To assess patient population at tertiary care hospital north India.Antibody was carried out 531 multi-transfused patients prior to crossmatching with commercially available three-cell panel (Diacell; Diamed AG, Cressier-sur-Morat,...
To study the seroprevalence of antibody to hepatitis B core antigen (anti-HBc) in healthy blood donors negative for HBsAg and evaluate whether anti-HBc detection could be adopted India as a screening assay HBV addition HBsAg.A total 1700 serum samples collected from HBsAg-negative were tested presence (IgM + IgG). All reactive then investigated anti-HBs liver function tests (LFTs). One hundred DNA by PCR method.Out tested, 142 (8.4%) found anti-HBc. It was significantly lower voluntary...
In India, at the majority of transfusion centers, antenatal antibody screening is done only in Rh (D) negative mothers. We report here two cases haemolytic disease newborn (HDN) by maternal alloimmunization to anti-c one case, and both anti-E second case. Both women were positive mothers HDN was detected postnatally a direct antiglobulin test (DAT) their newborns. These highlight importance routine even females. A close follow-up throughout pregnancy required if irregular antibodies are...
Encrusted cystitis is a rare condition characterized by encrustation of the bladder mucosa with associated chronic inflammation induced urea-splitting bacterial infection--most commonly, Corynebacterium urealyticum. Moreover, it usually occurs in immunocompromised patients, especially recipients renal transplants or patients history previous urological procedures. Due to rarity entity and slow growth species, appropriate treatment often delayed due difficulties diagnosis resistance numerous...
NUT carcinoma is an aggressive driven by the BRD4-NUT fusion oncoprotein, which activates chromatin to promote expression of progrowth genes. BET bromodomain inhibitors (BETi) are a promising treatment for that can impede BRD4-NUT's ability activate genes, but efficacy BETi as monotherapy limited. Here, we demonstrated enhancer zeste homolog 2 (EZH2), silences genes through establishment repressive chromatin, dependency in carcinoma. Inhibition EZH2 with clinical compound tazemetostat...
<b>Background: </b> To assess the appropriate utilization of platelet transfusions [random donor platelets (RDP) and single (SDP)]; a six-month retrospective audit was carried out in tertiary care hospital. <b> Materials Methods:</b> A from May to October 2005 estimate its preparation, wastage rate. Patient's demographics, transfusion triggers episodes ABO Rh (D) group specific or non-group were also assessed. Results: About 5525 units [PRP-PC, 3,813 (69%); BC-PC, 983 (17.8%); PRP, 648...
Mammary myofibroblastoma is a rare mesenchymal neoplasm that typically presents in older men and women. Less commonly, these benign tumors may also occur soft tissues located outside of the breast, which case they are referred to as mammary-type myofibroblastomas. The histologic composition this spindle cell tumor can be markedly varied. We present large mammary male patient discuss typical imaging makeup tumors.
Abstract Conventional tube testing was used for antibody screening and titration in D– pregnant women our hospital until the recent introduction of gel test. In this study we assessed sensitivity test setup tried to establish a correlation between these tests determining titer. We collected 652 blood samples from 223 antenatal during span 1 year. The were tested separately by conventional technique detection titration. detected 84 (12.8%) positive as compared with 93 (14.2%) test, indicating...
Abstract Objectives Tumor-infiltrating lymphocytes (TILs) have recently emerged as a prognostic factor in breast cancer. In our previous study, we proposed that tumor stroma should also be considered the calculation of TILs and introduced infiltration lymphocyte volume (TILV) triple-negative Methods We assessed disease-free survival predictive value TILV all subtypes invasive carcinoma compared with TILs. Differences between curves were determined by using log-rank test, Kaplan-Meier plots...
Nodular hidradenoma is an uncommon cutaneous adnexal tumor arising from sweat glands. In the skin, it usually presents as a solitary dermal nodule; excision curative in most cases. rare instances, may present breast mass and can mimic carcinoma clinically radiologically, causing diagnostic dilemmas for treating physician pathologist. Herein, we discuss case of nodular 20-year-old Hispanic woman rapidly growing that mimicked carcinoma. We presentation this differential diagnosis entity, well...