Yi Tat Tong

ORCID: 0000-0003-4621-5800
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About
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Research Areas
  • Microscopic Colitis
  • Cancer Immunotherapy and Biomarkers
  • Pancreatic and Hepatic Oncology Research
  • Eosinophilic Esophagitis
  • Pancreatitis Pathology and Treatment
  • Neuroendocrine Tumor Research Advances
  • Colorectal Cancer Treatments and Studies
  • Hematological disorders and diagnostics
  • Neonatal Health and Biochemistry
  • Monoclonal and Polyclonal Antibodies Research
  • Lymphoma Diagnosis and Treatment
  • Ion Transport and Channel Regulation
  • Neuropeptides and Animal Physiology
  • Platelet Disorders and Treatments
  • Uterine Myomas and Treatments
  • Receptor Mechanisms and Signaling
  • Endometrial and Cervical Cancer Treatments
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Adenosine and Purinergic Signaling
  • Neonatal Respiratory Health Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Retinopathy of Prematurity Studies
  • Cytokine Signaling Pathways and Interactions
  • Gene expression and cancer classification
  • Veterinary medicine and infectious diseases

The University of Texas MD Anderson Cancer Center
2021-2024

Memorial Hermann
2020-2021

The University of Texas Health Science Center at Houston
2018-2021

Jiangsu Provincial Hospital of Traditional Chinese Medicine
2011

Wuxi People's Hospital
2010

Nanjing Medical University
2010

Nihon University
2009

Background: Atherosclerosis leads to myocardial infarction (MI) and P2RY2 plays an important role in this process. The aim of the present study was investigate association between human MI via a haplotype-based case-control that additionally analyzed group by sex. Methods Results: 310 patients 254 controls were genotyped for 5 single-nucleotide polymorphisms (SNPs) gene (rs4944831, rs1783596, rs4944832, rs4382936, rs10898909). Data separately total, male, female subjects. For men, GA+AA...

10.1253/circj.cj-08-1198 article EN Circulation Journal 2009-01-01

Neoadjuvant FOLFIRINOX and gemcitabine/nab-paclitaxel (GemNP) therapies are increasingly used to treat patients with pancreatic ductal adenocarcinoma (PDAC). However, limited data available on their clinicopathologic prognosticators. We examined the factors survival of 213 PDAC who received 71 GemNP. The group was younger (p < 0.01) had a higher rate radiation = 0.049), borderline resectable locally advanced disease 0.001), Group 1 response 0.045) lower ypN stage 0.03) than GemNP group....

10.3390/cancers15092608 article EN Cancers 2023-05-04

We report a case of premature newborn girl with hospital course complicated by suspected respiratory syncytial virus pneumonitis for which she was placed on veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Despite phototherapy, her total bilirubin steadily increased to peak 50.4 mg/dL concern bilirubin-induced neurologic dysfunction, kernicterus.Therapeutic plasma exchange (TPE) achieved via connection the VA-ECMO circuit. Our institution's standard apheresis procedural...

10.1002/jca.21708 article EN Journal of Clinical Apheresis 2019-05-06

Context.— In the United States, review of digital whole slide images (WSIs) using specific systems is approved for primary diagnosis but has not been implemented intraoperative consultation. Objective.— To evaluate safety WSIs and compare efficiency glass slides (GSs) Design.— Ninety-one cases previously submitted frozen section evaluation were randomly selected from 8 different anatomic pathology subspecialties. GSs these scanned on a Leica Aperio AT2 scanner at ×20 magnification (0.25...

10.5858/arpa.2023-0105-oa article EN Archives of Pathology & Laboratory Medicine 2023-09-26

Howell-Jolly body-like inclusions have been previously associated with patients who are human immunodeficiency virus (HIV) infected, taking antiviral medications, and immunosuppressed. These appear in neutrophils resemble bodies of normoblasts abnormal erythropoiesis. In granulocytes, they thought to represent detached nuclear fragments produced from dysplastic granulopoiesis. To the best our knowledge, no association myelodysplastic syndrome (MDS) has reported previously.To establish an...

10.5858/arpa.2017-0328-oa article EN Archives of Pathology & Laboratory Medicine 2018-07-30

Adequate sampling is essential to an accurate pathologic evaluation of pancreatectomy specimens resected for pancreatic ductal adenocarcinoma (PDAC) after neoadjuvant therapy (NAT). However, limited data are available the association between and survival in these patients. We examined entire submission tumor (ESOT) pancreas (ESOP) with disease-free (DFS) overall (OS), as well their correlations clinicopathologic features, 627 patients PDAC who received NAT pancreaticoduodenectomy....

10.3390/cancers16193312 article EN Cancers 2024-09-27

Howell-Jolly body-like inclusions (HJBLIs) have been classically associated with human immunodeficiency virus (HIV)-infected patients, patients on antiviral medications, and immunosuppressed individuals. These appear in neutrophils, unlike Barr bodies, are completely detached the cytoplasm. They thought to represent nuclear fragments produced from dysplastic granulopoiesis. To best of our knowledge, no association HJBLIs myelodysplastic syndrome (MDS) has reported previously. Here we...

10.1093/ajcp/aqx121.184 article EN American Journal of Clinical Pathology 2018-01-01

A premature baby girl with a complicated hospital course developed RSV pneumonitis at 2 months of age for which she was placed on extracorporeal membrane oxygenation (ECMO). In spite earlier phototherapy, bilirubin steadily increasing and reached 50.4 mg/dL concern induced neurologic dysfunction. Exchange transfusion not recommended due to patient instability risk significant deterioration while ECMO. Plasma exchange (PLEX), although recognized as category treatment option hyperbilirubinemia...

10.1093/ajcp/aqx131.367 article EN American Journal of Clinical Pathology 2018-01-01

Regulatory T cells (Tregs) have been proposed to dampen functions of antineoplastic immune and thus promote cancer progression. They express CD25 transcription factor Forkhead box P3 (FOXP3). The method identify Tregs with CD25/FOXP3 double staining in the literature was mainly by flow cytometry analysis, which is not practical daily practice. Here, we investigate possibility using FOXP3/CD25 immunohistochemical tumor tissues. Tissue microarrays (TMAs) were manually built utilizing tissues...

10.1093/ajcp/aqy090.098 article EN American Journal of Clinical Pathology 2018-09-21

INTRODUCTION: While the histopathologic criteria for diagnosis of eosinophilic esophagitis (EoE) and related clinical endoscopic manifestations are well established, little is known about lymphocytic (LyE). The aim this study was to determine whether significant correlations exist between numbers intraepithelial lymphocytes (IEL) in esophageal biopsies usually associated with EoE. METHODS: H&E slides from 331 conscutive patients were reviewed. number IEL eosinophils (IEE) per mm 2...

10.14309/01.ajg.0000591156.39649.cf article EN The American Journal of Gastroenterology 2019-10-01
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