A5069644896- Sleep and related disorders
- Sleep and Wakefulness Research
- Circadian rhythm and melatonin
- Sleep and Work-Related Fatigue
- Heart Rate Variability and Autonomic Control
- Homelessness and Social Issues
- Impact of Light on Environment and Health
- Color perception and design
- Functional Brain Connectivity Studies
- Non-Invasive Vital Sign Monitoring
- Attention Deficit Hyperactivity Disorder
- Child Nutrition and Feeding Issues
- Work-Family Balance Challenges
- Infant Development and Preterm Care
- Health, psychology, and well-being
- Youth Substance Use and School Attendance
- Psychological and Temporal Perspectives Research
- COVID-19 and Mental Health
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Human-Automation Interaction and Safety
- Olfactory and Sensory Function Studies
- EEG and Brain-Computer Interfaces
- Perfectionism, Procrastination, Anxiety Studies
- Restless Legs Syndrome Research
National Institute of Mental Health
2016-2025
National Center of Neurology and Psychiatry
2016-2025
Kyushu University
2007-2008
Although evening preference has recently been identified as a risk factor for depression, it not substantiated whether is direct depressive states, or if associated secondarily through other factors, such delayed sleep timing and shortened duration. The objective of this study to investigate associations in Japanese adult subjects between incidence adjusting various parameters related states. Morningness-Eveningness Questionnaire (MEQ), the Pittsburgh Sleep Quality Index (PSQI), Center...
Objectives Sleep debt reportedly increases emotional instability, such as anxiety and confusion, in addition to sleepiness psychomotor impairment. However, the neural basis of instability due sleep has yet be elucidated. This study investigated changes responses that are elicited by simulation short-term loss brain regions responsible for these changes. Subjects Methods Fourteen healthy adult men aged 24.1±3.3 years (range, 20–32 years) participated a within-subject crossover consisting...
To assess circadian preference with a score, the Morningness-Eveningness Questionnaire (MEQ) has been used for more than 3 decades now. More recently, Munich ChronoType (MCTQ) was developed: it asks sleep-wake behavior on work and free days uses midpoint of sleep (MSF), corrected debt accumulated during week as an indicator chronotype (MSFsc). In this study, we developed Japanese version MCTQ by using translation/back-translation approach including examination its semantic validity....
A system of self-sustained biological clocks controls the 24-h rhythms behavioral and physiological processes such as sleep–wake cycle. The circadian clock is regulated by transcriptional translational negative feedback loops multiple genes. Polymorphisms in genes have been associated with morningness–eveningness (diurnal) preference, familial advanced sleep phase type (ASPT) delayed (DSPT). We genotyped single-nucleotide polymorphisms 182 DSPT individuals, 67 free-running (FRT) individuals...
Abstract In this study, we hypothesized that dynamics of sleep time obtained over consecutive days extended in a laboratory reflect an individual’s optimal duration (OSD) and the difference between OSD habitual (HSD) at home represents potential debt (PSD). We found varies among individuals PSD showed stronger correlation with subjective/objective sleepiness than actual time, interacting vulnerability loss. Furthermore, only 1 h takes four to recover their level. Recovery from was also...
This study aimed to develop an algorithm for determining sleep/wake states by using chronological data on the amount of physical activity (activity intensity) measured with FS-750 actigraph, a device that can be worn at waist, allows its downloaded home, and is suitable use in both sleep research remote medicine. Participants were 34 healthy young adults randomly assigned two groups, A (n =17) B =17), who underwent 8-hour polysomnography (PSG) laboratory environment. Simultaneous obtained...
Objectives To investigate childhood obstructive sleep apnea syndrome (OSAS) and its role in daytime sleepiness among school-age children. Methods A questionnaire survey was conducted with 25,211 children aged 6–15 (mean, 10.39) years attending 148 elementary 71 middle schools 10 prefectures across Japan their parents. Questions concerned 4 habit items (bedtime, onset latency, wake time after onset, wake-up time) disorder (loud snoring, snorts/gasps, breathing pauses, seems very sleepy the...
Misalignment between an individual's circadian phase and his/her environment due to social imposition is called jetlag (SJL). SJL has emerged as a public health concern, it contributes unhealthy lifestyle adverse outcomes. This study aimed elucidate the percentage of in large Japanese population using version Munich ChronoType Questionnaire (MCTQ). A total 10,000 participants responded web-based cross-sectional survey, final sample comprised 3708 (60.1% male; average age 45.1 [SD 13.4]...
Circadian typology, or "morningness" and "eveningness," is generally assessed using the Morningness-Eveningness Questionnaire (MEQ), a 19-item scale that could be burdensome in large-scale surveys. To overcome this, 5-item version known as reduced morningness-eveningness questionnaire (rMEQ), which sensitive to assessment of circadian was developed; however, validated Japanese rMEQ yet established. This study aimed develop validate rMEQ. Five essential items for were selected from existing...
Yuji Yamada, Naoko Kishimoto, Hiromi Tagata, Tsubasa Morimoto, Kazuho Tomimoto, Yutaro Sato, Yuko Higuchi, Hiroshi Hiejima, Hayato Ohshima, Takao Kato, Mari S. Oba, Shoki Izumi, Yui Tomo, Shingo Kitamura, Andrew Stickley, Toshifumi Takahiro Nemoto, Masafumi Mizuno, Hiroaki Tomita, Michio Suzuki, Motohiro Ozone, Kenji Hashimoto, Kazuo Mishima, Takashi Ohnishi, Kazuyuki Nakagome, Tomiki Sumiyoshi. Clin Psychopharmacol Neurosci -0001;0:. https://doi.org/10.9758/cpn.24.1258
The purpose of the present study was to clarify relationship between late-life depression and daily life stress in a representative sample 10 969 Japanese subjects.Data on adults aged > or =50 who participated Active Survey Health Welfare 2000, were analyzed. self-administered questionnaire included items 21 reasons for stressors magnitude stress, as well version Center Epidemiologic Studies Depression Scale (CES-D). incidence mild-moderate (D(16)) severe (D(26)) depressive symptoms examined...
Evaluation of circadian phenotypes is crucial for understanding the pathophysiology diseases associated with disturbed biological rhythms such as rhythm sleep disorders (CRSDs). We measured clock gene expression in fibroblasts from individual subjects and observed cells (in vitro rhythms). Period length period) was compared intrinsic period, τ, under a forced desynchrony protocol vivo circadian/sleep parameters evaluated by questionnaires, log, actigraphy. Although no significant correlation...
The aim of this study was to clarify the effects 45 min facial massage on activity autonomic nervous system, anxiety and mood in 32 healthy women. Autonomic assessed by heart rate variability (HRV) with spectral analysis. In analysis HRV, we evaluated high-frequency components (HF) low- ratio (LF/HF ratio), reflecting parasympathetic sympathetic activity, respectively. State Trait Anxiety Inventory (STAI) Profile Mood Status (POMS) were administered evaluate psychological status. score STAI...
Many modern people suffer from sleep debt that has accumulated in everyday life but is not subjectively noticed (potential [PSD]). Our hypothesis for this study was resolution of PSD through extension optimizes mood regulation by altering the functional connectivity between amygdala and prefrontal cortex. Fifteen healthy male participants underwent an experiment consisting a baseline evaluation followed two successive interventions, namely, 9-day one night total deprivation (TSD). Tests...
Patients with chronic insomnia are prone to long-term use of hypnotics. Reported risk factors include aging, female sex, and comorbid psychiatric disorders. However, most previous studies have been cross-sectional cohort studies.We conducted a retrospective study using medical service payment data for 330,000 people determine the duration prescription hypnotics use. We followed up 3981 patients (2382 M, 1599 F, age 40.3 ± 12.4 years) who were prescribed first time between April 2005 March...
Emotional information is frequently processed below the level of consciousness, where subcortical regions brain are thought to play an important role. In absence conscious visual experience, patients with cortex damage discriminate valence emotional expression. Even in healthy individuals, a subliminal mechanism can be utilized compensate for functional decline cognition various causes such as strong sleepiness. this study, sleep deprivation was simulated individuals investigate alterations...
This study examined the effects of odors on sustained attention during a vigilance task. Two essential oils (lavender and eucalyptus) two materials (l-menthol linalyl acetate) were compared with control. The increase in reaction time was significantly lower lavender than results suggest that administration helped to maintain long-term
Abstract We evaluated the circadian phenotypes of patients with delayed sleep–wake phase disorder (DSWPD) and non-24-hour rhythm (N24SWD), two different sleep disorders (CRSDs) by measuring clock gene expression rhythms in fibroblast cells derived from individual patients. Bmal1-luciferase ( Bmal1 - luc ) were measured primary skin biopsy samples DSWPD N24SWD, as well control subjects. The period length vitro period) was distributed normally 22.80±0.47 (mean±s.d.) h control-derived...
Objectives: Sleep debt reportedly increases emotional instability, such as anxiety and confusion, in addition to sleepiness psychomotor impairment.However, the neural basis of instability due sleep has yet be elucidated.This study investigated changes responses that are elicited by simulation short-term loss brain regions responsible for these changes.Subjects Methods: Fourteen healthy adult men aged 24.163.3 years (range, 20-32 years) participated a withinsubject crossover consisting 5-day...
There is a dearth of sleep questionnaires with few items and confirmed reliability validity that can be used for the early detection problems in children. The aim this study was to develop questionnaire assess its both children at high risk disorders community population. Data analysis were derived from two populations targeted by Children's Sleep Habits Questionnaire (CSHQ): 178 attending elementary school 432 who visited pediatric psychiatric hospital (aged 6–12 years). new constructed as...
This study aimed to reveal the associations between risk of new-onset type 2 diabetes and duration antidepressant use dose, after onset clinical outcomes.In this large-scale retrospective cohort in Japan, new users antidepressants (exposure group) nonusers (nonexposure group), aged 20-79 years, were included 1 April 2006 31 May 2015. Patients with a history or receipt antidiabetes treatment excluded. Covariates adjusted by using propensity score matching; analyzed use/dose exposure...
Abstract Background Blue-enriched white light at night has the potential to delay circadian rhythm in daily life. This study was conducted determine whether use of high correlated color temperature (CCT) home is associated with sleep timing university students. Methods The survey 2014–2015 447 students Japan and 327 China. Habitual type CCT were investigated by using a self-administered questionnaire. Japanese significantly later than Chinese bedtime, wake time, midpoint sleep. They asked...
Abstract In modern society, many people have insomnia. Chronic insomnia has been noted as a risk factor for depression. However, there are few functional imaging studies of the brain on affective functions in chronic This study aimed to investigate activities induced by emotional stimuli patients. Fifteen patients with primary and 30 age gender matched healthy controls participated this study. Both groups were presented images fearful, happy, neutral expressions consciously non-consciously...