A5060097127- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Music Therapy and Health
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- Infection Control and Ventilation
- Climate Change and Health Impacts
- Health disparities and outcomes
- Intensive Care Unit Cognitive Disorders
- Health, psychology, and well-being
- Smoking Behavior and Cessation
- Voice and Speech Disorders
- Lung Cancer Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Inhalation and Respiratory Drug Delivery
- Family and Patient Care in Intensive Care Units
- Health Promotion and Cardiovascular Prevention
- Chronic Disease Management Strategies
- Asthma and respiratory diseases
- Noise Effects and Management
- Psychosomatic Disorders and Their Treatments
- Injury Epidemiology and Prevention
- Advanced Technologies in Various Fields
- Diversity and Impact of Dance
Imperial College London
2019-2025
Royal Brompton Hospital
2019-2024
Lung Institute
2019-2024
NIHR Imperial Biomedical Research Centre
2020-2024
Harefield Hospital
2021-2024
Royal Brompton & Harefield NHS Foundation Trust
2020-2022
Respiratory Clinical Trials
2020-2022
Guy's and St Thomas' NHS Foundation Trust
2022
National Institute for Health Research
2022
National Health Service
2021
Background Data on the long-term pulmonary sequelae in COVID-19 are lacking. Purpose To assess symptoms, functional impairment, and residual abnormalities serial chest CT scans survivors discharged from hospital at up to 1-year follow-up. Materials Methods Adult patients with between March 2020 June were prospectively evaluated 3 months 1 year through systematic assessment of thoracic as part PHENOTYPE study, an observational cohort study survivors. Lung function testing was limited...
There are few evidence-based interventions for long COVID; however, holistic approaches supporting recovery advocated. We assessed whether an online breathing and wellbeing programme improves health related quality-of-life (HRQoL) in people with persisting breathlessness following COVID-19.
Abstract Isolation and loneliness are related to various aspects of health. Physical performance is a central component However, its relationship with isolation not well understood. We therefore assessed the between loneliness, different social isolation, physical over time. 8,780 participants from English Longitudinal Study Ageing, three times 8 years follow-up, were included. Measures included (Short Performance Battery), (modified UCLA Loneliness Scale), considered in ways (domestic...
Arts in Health interventions show potential to improve the quality of life people with chronic lung disease. Listening music, making and dance have accepted established roles lives without However, their utility disease management is infrequently considered by medical professionals. The aim this review examine use music treatment self-management Although evidence base currently limited, existing research suggests a range biopsychosocial benefits. As personalised medicine social prescribing...
Objectives To investigate the experience of people who continue to be unwell after acute COVID-19, often referred as ‘long COVID’, both in terms their symptoms and interactions with healthcare. Design We conducted a mixed-methods analysis responses survey accessed through UK online post-COVID-19 support information hub, between April December 2020, about people’s experiences having COVID-19. Participants 3290 respondents, 78% female, 92.1% white ethnicity median age range 45–54 years; 12.7%...
Abstract Background The COVID-19 pandemic is having profound psychological impacts on populations globally, with increasing levels of stress, anxiety, and depression being reported, especially in people pre-existing medical conditions who appear to be particularly vulnerable. There are limited data the specific concerns have about what these based on. Methods aim this study was identify explore long-term respiratory UK regarding impact how were affecting them. We conducted a thematic...
Around one in ten people who contract COVID-19 report persistent symptoms or 'long COVID'. Impaired mental health and well-being is commonly reported, including anxiety, depression reduced quality of life. However, there limited in-depth research exploring why are affected experiencing long COVID.
The impact of acute COVID-19 on people with asthma appears complex, being moderated by multiple interacting disease-specific, demographic and environmental factors. Research regarding longer-term effects in this group is limited. We aimed to assess impacts predictors persistent symptoms, asthma.Using data from an online UK-wide survey 4500 (median age 50-59 years, 81% female), conducted October 2020, we undertook a mixed methods analysis the characteristics experience those reporting having...
Aerosol particles of respirable size are exhaled when individuals breathe, speak and sing can transmit respiratory pathogens between infected susceptible individuals. The COVID-19 pandemic has brought into focus the need to improve quantification particle number mass exhalation rates as one route provide estimates viral shedding potential risk transmission viruses. Most previous studies have reported concentrations aerosol in an plume. We a robust assessment absolute from measurements minute...
Smoking is often colloquially considered "social". However, the actual relationship of smoking with current and future social isolation loneliness unclear. We therefore examined these relationships over a 12-year follow-up.
Objectives To assess the experience of people with long-term respiratory conditions regarding impact measures to reduce risk COVID-19. Design Analysis data (n=9515) from Asthma UK and British Lung Foundation partnership COVID-19 survey collected online between 1 8 April 2020. Setting Community. Participants 9515 self-reported conditions. 81% female, age ranges ≤17 years 80 above, all nations UK. Long-term reported included asthma (83%), chronic obstructive pulmonary disease (10%),...
Rising hospital admissions due to respiratory disease (RD) are a major challenge hospitals. This study explored modifiable social risk factors among 4478 older adults from the English Longitudinal Study of Ageing. Data were linked with administrative records and mortality registry data (follow-up 9.6 years) analysed using survival analysis accounting for competing risks. Living alone disengagement but not contact or loneliness associated an increased RD admissions, independent...
Objective: The study examined the nature and prevalence of factors associated with common mental disorders in primary care Vellore, South India. Method: Consecutive attenders ( N = 327) to a health facility were recruited. Results: One hundred eleven (33.9%) subjects satisfied criteria for disorders. Depression was presentation (83.8%). Indicators low socio-economic status (being debt, inability buy food, having less than three square meals per day) illiteracy significantly caseness....
the National Institute for Health and Care Excellence (NICE) (2007) states that 'respiratory rate is best marker of a sick patient first observation will indicate problem or deterioration in condition'. It therefore crucial staff are confident respiratory rates recorded accurately.to assess perceptions clinical regarding methods assessment reliability recordings charts.we developed questionnaire using practice guidelines. Some 41 ward-based completed questionnaires.confidence very low....
Singing for lung health (SLH) is a popular arts-in-health activity people with long-term respiratory conditions. Participants report biopsychosocial benefits, however, research on impact limited. The 'SLH: Improving Experiences of Lung Disease trial', randomised controlled, single (assessor) blind, trial 12 weeks SLH versus usual care chronic obstructive pulmonary disease (COPD) (n=120) was setup to help address this. first group (n=18, nine singing and controls) started face-to-face (five...
The coronavirus disease-19 (COVID-19) pandemic led to the prohibition of group-based exercise and cancellation sporting events. Evaluation respiratory aerosol emissions is necessary quantify exercise-related transmission risk inform mitigation strategies.Aerosol mass emission rates are calculated from concurrent ventilation data, enabling absolute comparison. An aerodynamic particle sizer (0.54-20 μm diameter) samples exhalate within a cardiopulmonary testing mask, at rest, while speaking...
Dietary nitrate supplementation, which improves skeletal muscle oxygen utilisation, vascular endothelial function and exercise capacity in people with chronic obstructive pulmonary disease, may benefit other lung conditions. In a double-blind, placebo-controlled, crossover study, 19 adults Group 3 hypertension who desaturated during exercise, 140 mL of nitrate-rich beetroot juice improved endurance shuttle walk time compared nitrate-depleted placebo (median (IQR) ESWT NR-BRJ 197 (140–273) s...
Background: Pulmonary rehabilitation(PR) is a highly effective intervention for people with chronic respiratory disease, however it not known how best to sustain its benefits. Clinical trials are needed establish if participation in Singing Lung Health(SLH) groups following PR will improve health-related quality-of-life, healthcare utilisation and exercise capacity compared usual care. A feasibility study would help guide development of these. Methods: In multi-centre, mixed-methods...
Introduction The British Lung Foundation (BLF) COPD Patient Passport ( www.blf.org.uk/passport ) was developed as a resource to help people with chronic obstructive pulmonary disease (COPD) and clinicians consider the care received identify essential omissions. We used online data collected evaluate delivery of in UK from patient perspective. Methods passport consists 13 questions relating key aspects including: spirometry confirmation diagnosis, understanding their support written...
Introduction UK guidelines suggest that pulse oximetry, rather than blood gas sampling, is adequate for monitoring of patients with COVID-19 if CO 2 retention not suspected. However, oximetry has impaired accuracy in certain patient groups, and data are lacking on its stepping down from intensive care unit (ICU) to non-ICU settings or being transferred another ICU. Methods We assessed the bias, precision limits agreement using 90 paired SpO SaO 30 (3 samples per patient). To assess between...
Objectives Lung cancer screening programmes offer an opportunity to address tobacco dependence in current smokers. The effectiveness of different approaches smoking cessation this context has not yet been established. We investigated if immediate support, including pharmacotherapy, offered as part a lung programme, increases quit rates compared usual care (Very Brief Advice and signposting services). Materials methods conducted single-blind randomised controlled trial smokers aged 55–75...