A5051131908- Head and Neck Cancer Studies
- Molecular Biology Techniques and Applications
- Cancer-related molecular mechanisms research
- Cervical Cancer and HPV Research
- CAR-T cell therapy research
- Esophageal Cancer Research and Treatment
- Cancer Immunotherapy and Biomarkers
- Cancer Research and Treatments
- Lung Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- RNA modifications and cancer
- Colorectal and Anal Carcinomas
- Head and Neck Surgical Oncology
- Immunotherapy and Immune Responses
- Radiomics and Machine Learning in Medical Imaging
- Salivary Gland Disorders and Functions
- Cancer Genomics and Diagnostics
- Systemic Sclerosis and Related Diseases
Icahn School of Medicine at Mount Sinai
2023-2025
Mount Sinai Hospital
2023-2025
Regeneron (United States)
2022
Abstract Purpose: Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in decreasing frequency as part of posttreatment surveillance for recurrence. Plasma tumor tissue modified viral (TTMV)-HPV DNA testing has emerged a biomarker which can inform disease status during surveillance. Experimental Design: This retrospective observational cohort study involved 543 patients who completed...
<p>Supplementary Figure S1: Case examples of false negative TTMV-HPV DNA results identified during surveillance</p>
<p>Supplementary Figure S1: Case examples of false negative TTMV-HPV DNA results identified during surveillance</p>
<div>Abstract<p>Background: Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in decreasing frequency as part of post-treatment surveillance for recurrence. Plasma tumor tissue modified viral (TTMV)-HPV DNA testing has emerged a biomarker which can inform disease status during surveillance. Methods: This retrospective observational cohort study involved 543 patients who...
Abstract Introduction: Indeterminate results of clinical or imaging examinations are common across the care continuum, and decisions made can lead to overtreatment psychological financial harms for patient. Additionally, due emergence highly sensitive circulating tumor DNA assays, an indeterminate status also arise when molecular detection precedes radiological evidence recurrence a period time. We recently reported &gt;99% negative &gt;95% positive predictive value tissue modified...
<div>AbstractPurpose:<p>Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in decreasing frequency as part of posttreatment surveillance for recurrence. Plasma tumor tissue modified viral (TTMV)-HPV DNA testing has emerged a biomarker which can inform disease status during surveillance.</p>Experimental Design:<p>This retrospective observational cohort study involved...
<p>Supplementary Figure S1: Case examples of false negative TTMV-HPV DNA results identified during surveillance</p>
<p>Supplementary Figure S1: Case examples of false negative TTMV-HPV DNA results identified during surveillance</p>
<div>Abstract<p>Background: Human papillomavirus (HPV) is causally linked to oropharyngeal squamous cell carcinoma (OPSCC). Consensus guidelines recommend clinical exams and imaging in decreasing frequency as part of post-treatment surveillance for recurrence. Plasma tumor tissue modified viral (TTMV)-HPV DNA testing has emerged a biomarker which can inform disease status during surveillance. Methods: This retrospective observational cohort study involved 543 patients who...