- Schizophrenia research and treatment
- Tryptophan and brain disorders
- Bipolar Disorder and Treatment
- Treatment of Major Depression
- Stress Responses and Cortisol
- Diet and metabolism studies
- Electroconvulsive Therapy Studies
- Neurotransmitter Receptor Influence on Behavior
- Child and Adolescent Psychosocial and Emotional Development
- Resilience and Mental Health
- Posttraumatic Stress Disorder Research
- Nerve injury and regeneration
- Autism Spectrum Disorder Research
- Pharmacological Effects and Toxicity Studies
- Cardiac Health and Mental Health
- Toxoplasma gondii Research Studies
- Mental Health and Psychiatry
- Pharmacogenetics and Drug Metabolism
- Suicide and Self-Harm Studies
- Electrolyte and hormonal disorders
- Attention Deficit Hyperactivity Disorder
- Hormonal Regulation and Hypertension
- Psychology of Development and Education
- Mental Health Research Topics
- Receptor Mechanisms and Signaling
University Hospital Centre Zagreb
2016-2025
University of Zagreb
2016-2025
Klinika za psihijatriju Vrapče
2014-2024
Hologic (Germany)
2024
University of Mostar
2017
University of Osijek
2016
Abstract This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest that is the third most toxic in United States (US), it produces four times higher pneumonia mortality than agranulocytosis or myocarditis. For trough steady-state serum concentrations, therapeutic reference range narrow, from 350 to 600 ng/mL with potential for toxicity ADRs as concentrations increase....
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Neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte (PLR), monocyte–lymphocyte (MLR) and systemic immune-inflammation index (SII index) are increasingly used as indicators of inflammation in different conditions, including schizophrenia. However, their relationship with negative symptoms, anhedonia, is largely unknown. Included were 200 patients schizophrenia 134 healthy controls (HC), assessed for physical anhedonia (PA), using the Revised Physical Anhedonia Scale (RPAS), social (SA) by...
A recent article in this journal presented a US perspective regarding the modernization of clozapine prescription and proposed an escape from long shadow cast by agranulocytosis.Here, international group collaborators discusses point view complementary to focusing on worldwide outcomes usage that may be uneven terms frequency adverse drug reactions.Studies Scandinavian national registries (Finland Denmark) did not find increased mortality patients or any clear evidence alleged toxicity...
Abstract We examined and compared the relationship between religiosity symptom severity in patients with major depressive disorder (MDD) rated by Hamilton Depression Rating Scale) schizophrenia (rated Positive Negative Syndrome Scale). The Duke University Religion Index, Santa Clara Strength of Religious Faith (SCSORF) questionnaire, Brief Coping scale scores were similar MDD ( n = 50) 50). In MDD, higher organizational religious activity (ORA) (estimate 2.28, 95% confidence interval [CI]...
Vuksan-Cusa B, Sagud M, Jakovljevic Mihaljevic Peles A, Jaksic N, S, Zivkovic Kudlek Mikulic Jevtovic S. Association between C-reactive protein and homocysteine with the subcomponents of metabolic syndrome in stable patients bipolar disorder schizophrenia. Nord J Psychiatry 2012;Early Online:1–6. Background: Previous studies revealed high prevalence (MetS) C-Reactive (CRP) have also both emerged as independent risk factors for development cardiovascular disease (CVD) but are less...
Abstract Objective This cross‐sectional study investigated the association of physical and social anhedonia with suicidality in patients major depressive disorder (MDD), schizophrenia, non‐psychiatric controls. Method All participants completed revised Physical Anhedonia Scale (RPAS) Social (RSAS) were subdivided according to positive life‐time suicide attempt history. MDD evaluated Montgomery‐Ãsberg Depression Rating (MADRS), healthy respondents Patient Health Questionnaire‐9 (PHQ‐9),...
Objective: Nightmares and insomnia in combat‐related post‐traumatic stress disorder (PTSD) might be resistant to treatment with selective serotonin reuptake inhibitors (SSRIs) benzodiazepines. Method: We describe five case reports of patients suffering from long‐lasting intractable nightmares insomnia. They were given different psychotropic agents past few years, no improvement their sleep disturbance. Olanzapine was added the current regimen. Results: Both improved rapidly after olanzapine...
Extrapyramidal symptoms (EPSs) are common adverse effects of antipsychotics. The development acute EPSs could depend on the activity dopaminergic system and its gene variants. aim this study was to determine association between type 2 receptor (DRD2) dopamine transporter (SLC6A3) catechol-O-methyltransferase (COMT) polymorphisms in 240 male schizophrenic patients treated with haloperidol (15-mg/d) over a period weeks. Acute were assessed Simpson-Angus Scale. Three polymorphisms, DRD2 Taq1A,...