Zhigang Zhang

ORCID: 0000-0001-9624-9668
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About
Contact & Profiles
Research Areas
  • Tattoo and Body Piercing Complications
  • Ear Surgery and Otitis Media
  • Syphilis Diagnosis and Treatment
  • Hearing, Cochlea, Tinnitus, Genetics
  • Vestibular and auditory disorders
  • Congenital Ear and Nasal Anomalies
  • Sinusitis and nasal conditions
  • Streptococcal Infections and Treatments
  • Plant Molecular Biology Research
  • Ichthyology and Marine Biology
  • Electromagnetic wave absorption materials
  • Ear and Head Tumors
  • Hearing Loss and Rehabilitation

Sun Yat-sen Memorial Hospital
2023-2025

Sun Yat-sen University
2023-2025

Cisplatin is widely employed in clinical oncology as an anticancer chemotherapy drug practice and known for its severe ototoxic side effects. Prior research indicates that the accumulation of reactive oxygen species (ROS) plays a pivotal role cisplatin's inner ear toxicity. Hesperidin flavanone glycoside extracted from citrus fruits has anti-inflammatory antioxidant Nonetheless, specific pharmacological actions hesperidin alleviating cisplatin-induced ototoxicity remain elusive. The...

10.1080/13510002.2024.2341470 article EN cc-by-nc Redox Report 2024-04-17

ABSTRACT Background Patients with Turner syndrome (TS) commonly experience acute otitis media and Eustachian tube dysfunction (ETD). Comparison of the anatomical features (ET) between TS patients age‐matched controls may provide insights into high prevalence ETD in TS. Methods This study compared ET angle, length, diameters bone segment, bone–cartilage (BC) junction, pharyngeal opening control children. A subgroup analysis was also conducted to explore potential risk factors for patients....

10.1002/lary.32086 article EN The Laryngoscope 2025-02-20

Objectives To determine the morphologies and effect of round window niche veil (RWNV) on local drug delivery efficacy develop diagnostic criteria high‐resolution computed tomography (HRCT). Methods Patients diagnosed with otosclerosis, bilateral profound sensorineural hearing loss or vestibular schwannoma were enrolled from 2019 to 2022, receiving temporal bone HRCT scanning, anatomic variations RWMV summarized intraoperative. For patients schwannoma, 1 mL dexamethasone solution (4 mg/mL)...

10.1002/lary.31006 article EN The Laryngoscope 2023-08-28

Chronic otitis media (COM) is an inflammatory disease that commonly presents with otorrhea and hearing loss. Bacteria-induced inflammation can cause inner ear damage, leading to sensorineural loss (SNHL). This study aimed compare the prevalence severity of SNHL in patients gram-negative versus gram-positive cultures examine associations between concentrations circulating monocytes neutrophils bacteria species SNHL.

10.1002/lary.31322 article EN The Laryngoscope 2024-02-08

The authors declare that they have no known competing financial interests or personal relationships could appeared to influence the work reported in this paper. conflicts of interest. peer review history for article is available at https://www.webofscience.com/api/gateway/wos/peer-review/10.1111/coa.14224. confirm data supporting findings study are within article.

10.1111/coa.14224 article EN Clinical Otolaryngology 2024-10-22
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