A5108054033- Liver physiology and pathology
- Pancreatic function and diabetes
- Liver Disease Diagnosis and Treatment
- Human Health and Disease
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Diet, Metabolism, and Disease
- Biochemical effects in animals
- Tissue Engineering and Regenerative Medicine
- 3D Printing in Biomedical Research
- School Health and Nursing Education
Southern Medical University
2023
Nanjing Drum Tower Hospital
2019
Nanjing University
2008-2010
Nanjing Medical University
2008
As yet, there was no effective pharmacological therapy approved for non-alcoholic fatty liver disease (NAFLD). Here, we aimed to evaluate the therapeutic potential of puerarin against NAFLD and explored underlying mechanisms. C57BL/6J mice were fed with a high-fat high-sucrose (HFHS) diet or without coadministration intragastrically. The levels hepatocellular injury, steatosis, fibrosis, mitochondrial metabolism alteration detected. First, ameliorated histopathologic abnormalities due HFHS....
Background: Diabetic cardiomyopathy (DCM) is a prevalent complication observed in diabetic patients. The long non-coding RNA maternally expressed gene 3 ( lncMEG3 ) has been found to be intricately associated with myocardial infarction and heart failure. However, the role of DCM remains unclear. present study was designed investigate elucidate underlying molecular mechanisms. Methods: mouse model established through intraperitoneal injection streptozotocin (STZ). heart-targeted...
The availability of well-characterized human hepatocytes that can be frozen and thawed will critical for cell therapy. We addressed whether recover after microencapsulated cryopreservation investigated these cryopreserved used clinical applications.Adult 18 separate donors were isolated with a two-step extracorporeal collagenase perfusion technique. After pre-incubation at 4 degrees C 12-24 h in HepatoZYME-SFM, using alginate-poly-L-lysine-alginate microcapsules. transferred to complete...