A5057553955- Advanced Sensor and Energy Harvesting Materials
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Tissue Engineering and Regenerative Medicine
- Conducting polymers and applications
- Neuroscience and Neural Engineering
- Graphene research and applications
- Bone Tissue Engineering Materials
- Advanced Materials and Mechanics
- Hydrogels: synthesis, properties, applications
- Planarian Biology and Electrostimulation
- Supramolecular Self-Assembly in Materials
- Pancreatic function and diabetes
- Supercapacitor Materials and Fabrication
- MXene and MAX Phase Materials
- Tactile and Sensory Interactions
- Polydiacetylene-based materials and applications
- 3D Printing in Biomedical Research
- RNA Interference and Gene Delivery
- Muscle activation and electromyography studies
- Advanced biosensing and bioanalysis techniques
- Liver physiology and pathology
- biodegradable polymer synthesis and properties
- Dendrimers and Hyperbranched Polymers
- Advancements in Transdermal Drug Delivery
Nanjing University of Science and Technology
2016-2025
Southeast University
2009-2019
University of Akron
2018-2019
State Key Laboratory of Digital Medical Engineering
2009-2018
BioElectronics (United States)
2018
Sun Yat-sen University
2011-2013
University of Michigan–Ann Arbor
2012
Nanjing Drum Tower Hospital
2009
Abstract Fabrication of soft piezoelectric nanomaterials is essential for the development wearable and implantable biomedical devices. However, a big challenge in this functional material to achieve high property with long‐term stability biological environment. Here, one‐step strategy fabricating core/shell poly(vinylidene difluoride) (PVDF)/dopamine (DA) nanofibers (NFs) very β‐phase content self‐aligned polarization reported. The self‐assembled structure believed formation alignment PVDF,...
Zwitterionic materials demonstrate the strong surface hydration to empower their antifouling property.
Soft graphene nanofibers with recoverable electrical conductivity and excellent physicochemical stability are prepared by a controlled assembly technique. By using the soft for cellular stimulation, common inhibitory effect of long-term stimulation on nerve growth development is avoided, which usually happens traditional 2D conductive materials. As service to our authors readers, this journal provides supporting information supplied authors. Such materials peer reviewed may be re-organized...
The long-segment peripheral nerve injury (PNI) represents a global medical challenge, leading to incomplete tissue recovery and unsatisfactory functional reconstruction. However, the current electrical stimulation (ES) apparatuses fail perfect repair due their inability of variable synchronous self-regulated function with physiological states. It is urgent develop an implantable ES platform physiologically adaptive provide instantaneous nerve-preferred ES. Here, signal generated by...
The rapid development of a self-powered system (SPS) has aroused an increasing interest in the field wearable electronics. current trend electronics is toward integration, portability, miniaturization, and sustainability. Hence, piezoelectric-driven patterned electrochromic supercapacitor (ESC) presented here, which integrated with energy harvesting, conversion, storage indication technologies. polyaniline (PANI) electrodes electrodeposited by coupling cyclic voltammetric galvanostatic...
Implantable pressure biosensors show great potential for assessment and diagnostics of pressure-related diseases. Here, we present a structural design strategy to fabricate core/shell polyvinylidene difluoride (PVDF)/hydroxylamine hydrochloride (HHE) organic piezoelectric nanofibers (OPNs) with well-controlled self-orientated nanocrystals in the spatial uniaxial orientation (SUO) β-phase-rich fibers, which significantly enhance performance, fatigue resistance, stability, biocompatibility....
Abstract Electrical stimulation (ES) is widely used in physiological and medical sciences, while its application to treat inflammatory skin diseases (ISDs) remains a challenge owing their natural pathological cuticle barrier lack of an effective combination with chemotherapy achieve specific immunomodulation. Here, wearable, battery‐free, multi‐component drug‐loaded electronic microneedle (mD‐eMN) system developed by integrating remodeled metal microneedles loaded chemical drugs flexible...
Electrospun nanofibers were widely studied to be applied as potential materials for tissue engineering. A new technology make poly-l-lactic acid/chitosan core/shell from heterologous solution by coaxial electrospinning technique was designed vascular gasket. Chitosan surface cross-linked genipin and modified heparin. Different ratios of PLA/CS in optimize the morphology fibers. Clean core-shell structures formed with a ratio at 1:3. Superior biocompatibility mechanical properties obtained...
Abstract Invasive electrical stimulation (iES) is prone to cause neural stimulus-inertia owing its excessive accumulation of exogenous charges, thereby resulting in many side effects and even failure nerve regeneration functional recovery. Here, a wearable iES system well designed built for bionic long-lasting modulation. It can automatically yield biomimetic pulsed signals under the driven respiratory motion. These are full unique physiological synchronization give biofeedback behaviors,...
Abstract Peripheral nerve injury (PNI) remains an intractable challenge in regenerative medicine. Recently, physical cue‐based strategies (e.g., electrical neurostimulation, acoustic radiation, electromagnetic bioregulation, as well directional fiber guiding, etc.) have drawn increasing attention not only a stimulator for cell functions modulation and fate determination, but also morphology‐index modulating phenotype, proliferation, differentiation, especially cells. More importantly, the...
Abstract Bionic electrical stimulation (Bio‐ES) aims to achieve personalized therapy and proprioceptive adaptation by mimicking natural neural signatures of the body, while current Bio‐ES devices are reliant on complex sensing computational simulation systems, thus often limited low‐fidelity simulated signals, failure interface information interaction due mechanical mismatch between soft tissues rigid electrodes. Here, study presents a flexible ultrathin self‐sustainable bioelectronic patch...
Three dimensional (3D) cell culture in functional scaffolds to mimic the natural growth state is important for construction of based implants vitro tissue engineering applications. Herein, we report a novel fluffy polypyrrole (PPy) fibrous scaffold (fluffy-PPy scaffold) fabricated by means an improved electrospinning process combined with situ surface polymerization, which PPy hollow fibers are discrete from one another deep interconnected pores ∼100 μm. This unique spatial structure permits...
Development of tough and adhesive hydrogels is critical for different applications, including wound dressing, soft robotics, wearable devices. However, achieving strong reversible adhesion between surfaces have proved to be a great challenge, because are the two highly desirable but opposite properties hydrogel adhesives. Existing adhesives possess either one-time, irreversible, or weak on diverse surfaces. Herein, we developed fully physically cross-linked double-network (DN) Agar/pAAEE...
Tough and adhesive hydrogels have shown great potential in wearable devices, flexible electronics, human–machine interfaces. However, most existing tough weak surface adhesion, or highly low mechanical strength. It remains a long-standing challenge to develop the with both properties. Here, we design fabricate fully physical double network hydrogel of Agar/pHEAA-AAc-Fe3+, which consisted first Agar by hydrogen bonds second poly(N-hydroxyethyl acrylamide) (pHEAA)-AAc-Fe3+ multiple ionic...
Dual network (DN) hydrogels with excellent mechanical strength and controllable component adjustment characteristics have a broad application range in the field of biomedicine. However, tissue adhesion, skin affinity, self-healing, antibacterial properties DN are inadequate for their as patches. In this work, we prepared dopamine/zinc oxide (DOPA/ZnO) doped poly(N-hydroxyethyl acrylamide) (p(HEAA))/agar combined them to obtain bilayer hydrogel (two-layer gel) moisturizing properties. Upon...