A5017257182- Supramolecular Self-Assembly in Materials
- Chemical Synthesis and Analysis
- Foreign Language Teaching Methods
- Hydrogels: synthesis, properties, applications
- SARS-CoV-2 and COVID-19 Research
- Genetic Associations and Epidemiology
- Business and Economic Development
- Silk-based biomaterials and applications
- Respiratory viral infections research
- Force Microscopy Techniques and Applications
- Virology and Viral Diseases
- Peptidase Inhibition and Analysis
- Enzyme Structure and Function
- Immune responses and vaccinations
- Cancer Genomics and Diagnostics
- Pharmacogenetics and Drug Metabolism
- Neurogenetic and Muscular Disorders Research
- Molecular Junctions and Nanostructures
- Neurological disorders and treatments
- Spectroscopy and Quantum Chemical Studies
- Microbial infections and disease research
- Protein Structure and Dynamics
- Genomics and Rare Diseases
- Bacteriophages and microbial interactions
- Click Chemistry and Applications
Stanford University
2021-2022
Mississippi State University
2020-2022
Stanford Medicine
2020
Massachusetts Institute of Technology
2008-2013
École Polytechnique Fédérale de Lausanne
2010
Previously we reported emulsion polymerization of propylene sulfide with Pluronic F127 as an emulsifier, yielding nanoparticles (NPs) in the 25 nm size range. Immunologically functional NPs were prepared by adding antigen−Pluronic conjugate to mixture (Reddy, S. T., et al. (2007) Nat. Biotechnol. 25, 1159). We sought a more flexible scheme for conjugation antigens and other biomolecules NP surfaces that would allow milder reaction conditions than achievable during step. Here, present...
The functionalization of self-assembling peptide scaffolds with biologically active motifs presents many possibilities for the design synthetic biological materials 3D cell culture, reparative, regenerative medicine and tissue engineering. We here report development short designed especially migration. VEVK9 (Ac-VEVKVEVKV-CONH2) VEVK12 (Ac-VEVKVEVKVEVK-CONH2) modified variants these peptides directly coupled to motifs. These include two-unit RGD binding units (PRGDSGYRGDS), adhesion...
Abstract Hydrogels formed from self‐assembling synthetic oligopeptides have been studied for almost 2 decades use in tissue engineering and drug delivery. Although a great deal has learned about the microstructure of these materials, there remain questions how peptide filaments are ordered to form gel. These unanswered leave disconnect between our understanding observed nanoscale mechanical properties macroscale gels they constitute. This study helps bridge this gap by examining role...
The SARS-CoV-2 pandemic has differentially impacted populations across race and ethnicity. A multi-omic approach represents a powerful tool to examine risk multi-ancestry genomes. We leverage tracking strategy in which we sequence viral host genomes transcriptomes from nasopharyngeal swabs of 1049 individuals (736 positive 313 negative) integrate them with digital phenotypes electronic health records diverse catchment area Northern California. Genome-wide association disaggregated by...
During COVID19 and other viral pandemics, rapid generation of host pathogen genomic data is critical to tracking infection informing therapies. There an urgent need for efficient approaches this at scale. We have developed a scalable, high throughput approach generate fidelity low pass whole genome HLA sequencing, genomes, representation human transcriptome from single nasopharyngeal swabs patients.
This study examines the possible impact of selected antecedents (interdepartmental conflict, university administration emphasis, reward system) on individual components (customer orientation, competitor interfunctional coordination) market orientation toward students within higher education.Prior research is extended and variable relationships are examined from four different department chair perspectives (accounting chairs, marketing males, females).Intelligence gathered survey using...
ABSTRACT The SARS-CoV-2 pandemic has differentially impacted populations of varied race, ethnicity and socioeconomic status. Admixture mapping local ancestry inference represent powerful tools to examine genetic risk within multi-ancestry genomes independent these confounding social constructs. Here, we leverage a tracking strategy in which sequence viral host transcriptomes from 1,327 nasopharyngeal swab residuals integrate them with digital phenotypes electronic health records. We...
This study examines the possible impact of selected antecedents (interdepartmental conflict, university administration emphasis, reward system) on individual components (customer orientation, competitor interfunctional coordination) market orientation toward students within higher education.Prior research is extended and variable relationships are examined from four different department chair perspectives (accounting chairs, marketing males, females).Intelligence gathered survey using...