A5029418344- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Diet and metabolism studies
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Marine animal studies overview
- Immune Cell Function and Interaction
- Virus-based gene therapy research
- Herpesvirus Infections and Treatments
- Foreign Language Teaching Methods
- Mercury impact and mitigation studies
- Immunodeficiency and Autoimmune Disorders
- Cytomegalovirus and herpesvirus research
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Aquaculture disease management and microbiota
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Signaling Pathways in Disease
- Viral Infections and Vectors
- Educational Methods and Teacher Development
- Animal Virus Infections Studies
- Marine Toxins and Detection Methods
- Cardiomyopathy and Myosin Studies
- Turtle Biology and Conservation
- Cephalopods and Marine Biology
Marine Mammal Center
2021-2025
The Ohio State University
2019-2023
MBio Diagnostics (United States)
2023
Columbus Zoo and Aquarium
2023
Health Center
2023
Florida State University
2016
Klebsiella pneumoniae is a Gram-negative, facultative anaerobic, and non-motile bacillus frequently observed in mammals. A hypermucoviscous (HMV) phenotype of K. reported stranded California sea lions (CSL) causing pleuritis bronchopneumonia as persistent cause strandings. We describe an increase cases HMV non-HMV CSLs along the coast between 2017 to 2022. 2,146 live-stranded were rescued by The Marine Mammal Center (Sausalito, California). 47 these tested positive for , with rise annual...
The cotton rat (Sigmodon hispidus) is an excellent small animal model for human respiratory viral infections such as syncytial virus (RSV) and metapneumovirus (HMPV). These infections, well other pulmonary inflammatory diseases asthma, are associated with lung mechanic disturbances. So far, the pathophysiological effects of infection allergy on lungs have not been measured, although this information might be important tool to determine efficacy vaccine drug candidates. To characterize...
Feline infectious peritonitis (FIP) is a systemic disease in felid species caused by infection with mutated forms of feline coronavirus (FCoV), and outbreaks can devastate exotic populations human care. was diagnosed three four related juvenile sand cats (Felis margarita) from single institution over 6-wk period. Case 1 7-mon-old male found deceased no premonitory signs. 2, an 8-mon-old (littermate to 1), 3, 6-mon-old (from different litter identical parentage), were evaluated for lethargy...
Thirteen pronghorn antelope (Antilocapra americana) from a single captive herd at the Columbus Zoo and Aquarium underwent complete or partial necropsies between 1997 2016. Ten of 13 animals had histologic evidence amyloidosis resulting in 77% prevalence. Histologic ultrastructural changes were characterized an attempt to determine underlying cause amyloid. Amyloid detection was performed through examination hemotoxylin eosin Congo red–stained microscopic slides for all animals. Transmission...
Human respiratory syncytial virus (RSV) is a leading cause of lower tract infection in infants and young children worldwide. The attachment (G) protein RSV synthesized by infected cells both membrane bound (mG) secreted form (sG) uses CX3C motif for binding to its cellular receptor. Cell culture mouse studies suggest that the G mimics cytokine CX3CL1 CX3CR1 on immune cells, which thought increased pulmonary inflammation vivo . However, because these have used lacking gene or blockade with...
Enteritis is a common cause of morbidity and mortality in lorikeets that can be challenging to diagnose treat. In this study, we examine gut microbiota two lorikeet flocks with enteritis (Columbus Zoo Aquarium-CZA; Denver Zoo-DZ). Since 2012, the CZA flock has experienced repeated outbreaks despite extensive diet, husbandry, clinical modifications. 2018, both DZ observed spike enteritis. Recent research revealed influence susceptibility enteropathogens. We hypothesized dysbiosis, or...
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral pneumonia in infants young children worldwide. Currently no vaccine available to prevent RSV infection, but virus-neutralizing monoclonal antibodies can be given prophylactically, emphasizing protective potential antibodies. One concept vaccinology mothers' immunization induce high antibody titers, passive transfer levels maternal fetus through placenta neonate colostrum. Cotton rats are an excellent small...
Recently, a novel gammaherpesvirus, miroungine gammaherpesvirus 3 (MirGHV3), was described in two juvenile elephant seals (Mirounga angustirostris) with diffuse large B-cell lymphoma. We developed and validated quantitative (q)PCR for rapid detection of MirGHV3 investigated its potential association duplex probe-hybridization qPCR DNA polymerase (pol) as the target gene. Each primer-probe combination cross-validated against others. Interference not seen when they were run same well assay....
We report the first case series of osteofluorosis in free ranging marine mammals and documentation baseline bone fluoride concentrations this population; however, exact source is not known. A stranded subadult male California sea lion, one carcass, partial presumably adult male, demonstrated osseous (bony) proliferations on various appendicular axial bones. The most severe lesions were from index with symmetrical segmental circumferential periosteal new proliferation diaphysis both femurs...
Abstract Background Enteritis is a common cause of morbidity and mortality in lorikeets that can be challenging to diagnose treat. In this study, we examine gut microbiota two lorikeet flocks with enteritis (Columbus Zoo Aquarium – CZA; Denver - DZ). Since 2012, the CZA flock has experienced repeated outbreaks despite extensive diet, husbandry, clinical modifications. 2018, both DZ observed spike enteritis. Recent research revealed influence susceptibility enteropathogens. We hypothesized...