A5057503524- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Cardiovascular and exercise physiology
- Long-Term Effects of COVID-19
- Delphi Technique in Research
- Chronic Disease Management Strategies
- Asthma and respiratory diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Nursing Diagnosis and Documentation
- Telemedicine and Telehealth Implementation
- Intensive Care Unit Cognitive Disorders
- Muscle activation and electromyography studies
- Pulmonary Hypertension Research and Treatments
- Health and Well-being Studies
- Stroke Rehabilitation and Recovery
- COVID-19 and Mental Health
- Nutrition and Health in Aging
- Myasthenia Gravis and Thymoma
- Family and Patient Care in Intensive Care Units
- Musicians’ Health and Performance
- Trauma and Emergency Care Studies
- Optimism, Hope, and Well-being
- COVID-19 and healthcare impacts
- Cardiac Health and Mental Health
- Diabetes Management and Education
NIHR Leicester Biomedical Research Centre
2015-2024
Nottingham University Hospitals NHS Trust
2022-2024
University of Nottingham
2019-2023
Nottingham Biomedical Research Centre
2022
National Institute for Health Research
2022
West Suffolk NHS Foundation Trust
2021
University Hospitals of Leicester NHS Trust
2012-2020
Glenfield Hospital
2012-2019
University of Leicester
2015-2019
NIHR Leicester Respiratory Biomedical Research Unit
2016
<b>Objective</b> To investigate whether an early rehabilitation intervention initiated during acute admission for exacerbations of chronic respiratory disease reduces the risk readmission over 12 months and ameliorates negative effects episode on physical performance health status. <b>Design</b> Prospective, randomised controlled trial. <b>Setting</b> An cardiorespiratory unit in a teaching hospital medical affiliated district general hospital, United Kingdom. <b>Participants</b> 389...
Rationale: Hospitalization represents a major event for the patient with chronic respiratory disease. There is high risk of readmission, which over longer term may be related more closely to underlying condition patient, such as skeletal muscle dysfunction.Objectives: We assessed hospital readmission at 1 year, including measures lower limb part larger clinical trial.Methods: Patients hospitalized an exacerbation disease underwent function quadriceps ultrasound. Independent factors...
Acute admission to hospital for an exacerbation of chronic respiratory disease (CRD) may impair skeletal muscle mass and function. We measured quadriceps thickness (Q thick ), as a surrogate marker mass, at admission, discharge, 6 weeks 3 months in 55 patients with CRD. Q fell by 8.3% during the period hospitalisation, which was sustained weeks, only partially recovered months. Sustained loss most marked readmitted follow-up period. reduction occurs prolonged variable recovery, is prevented...
Abstract Background Neuromuscular electrical stimulation (NMES) has shown to improve skeletal muscle strength and exercise capacity in stable patients with chronic obstructive pulmonary disease (COPD). Variations NMES protocols are considerable. We aimed compare changes after high‐frequency low‐frequency admitted hospital an acute exacerbation of COPD. Methods Patients were referred for inpatient (IP) rehabilitation during hospitalisation worsening their They received 30‐minute daily both...
The endurance shuttle walk test (ESWT) is frequently used as an outcome measure for pulmonary rehabilitation (PR). minimal important difference (MID) the ESWT after a course of has not been conclusively confirmed in literature. aim was to establish MID following 6-week PR programme patients with chronic obstructive disease (COPD). Following completion programme, data from 531 participants were included analysis estimate using both anchor-based and distribution-based methods. Mean age...
ABSTRACT Background and objective Establishing the amount of inpatient physical activity (PA) undertaken by individuals hospitalized for chronic respiratory disease is needed to inform interventions. This observational study investigated whether PA changes when a person an inpatient, how long required obtain representative measures varies within day between patients differing lengths stay. Methods A total 389 participants were recruited as early possible into their hospitalization. Patients...
Introduction National guidance for chronic obstructive pulmonary disease (COPD) suggests that self-management support be provided patients. Our institution has developed a standardised, manual-based, supported programme: Self-Management Programme of Activity Coping and Education (SPACE COPD(C)). SPACE was previously piloted on 1-2-1 basis, delivered by researchers, to individuals with COPD. Discussions stakeholders highlighted considerable interest in delivering the COPD(C) intervention as...
COPD is characterized by reduced exercise tolerance, and improving physical performance an important therapeutic goal. A variety of tests are commonly used to assess including laboratory field-based tests. The responsiveness these various common interventions yet be compared, but the results may inform test selection in clinical research settings.
Chronic obstructive pulmonary disease (COPD) is characterized in the later stages by acute exacerbations that often require hospitalization. Pulmonary rehabilitation recommended for patients with COPD to aid symptom control, improve quality of life and increase physical activity. We have previously reported a large intervention trial commenced during hospital admission. The aim this sub-study was evaluate patients’ experiences discharge following hospitalization an exacerbation COPD. During...
<h3>BACKGROUND:</h3> COPD is characterized by expiratory flow limitation, which results in symptomatic dyspnea and reduced exercise capacity. Changes breathing mechanics mean the respiratory muscles are unable to respond ventilatory demands, increasing sensation of dyspnea. A high-frequency oscillating device has been developed improve patients with COPD. We conducted a feasibility trial gain insight into potential for recruitment, retention, study design future randomized controlled trial....
This document has been produced to support providers of pulmonary rehabilitation (PR) services in response numerous requests for guidance received by the ACPRC during COVID-19 pandemic date. The and associated national measures reduce transmission have significantly impacted healthcare provision across UK. Following outbreak, many ‘non-essential’ adapted order provide a partially or fully remotely delivered service (telephone video-conferencing) continue serve their local population. A...
Survivors of COVID-19 can present with varied and persisting symptoms, regardless hospitalisation. We describe the ongoing quality life return to work status in a cohort non-hospitalised survivors respiratory symptoms presenting clinic, who consented completed patient-reported outcome measures. identified fatigue, reduced dysregulated breathing alongside breathlessness. Those co-existent fatigue had worse mood were less likely have returned normal working arrangements compared those without...
We investigated whether the differences in exercise limitation between patients with chronic obstructive pulmonary disease (COPD) or heart failure (CHF) affect repeatability responsiveness of incremental tests. Patients COPD (Medical Research Council dyspnoea grade 2–5) and CHF (New York Heart Association class II–IV) performed two shuttle walk tests (ISWT) following familiarisation cycle ergometer (ICE) within 2 weeks. Both were repeated on completion a rehabilitation (PR) programme. One...
<b>Introduction:</b> Patients with chronic pulmonary disease (CPD) often report symptoms affecting daily activities and quality of life, as well anxiety depression. <b>Objectives:</b> To establish prevalence depression in patients admitted acute exacerbation CPD, its association baseline MRC score. <b>Methods:</b> Data were analysed from a cohort 389 (45% male) recruited to single-blinded randomised control trial investigating rehabilitation on rehospitalisation. Hospital Anxiety Depression...
<b>Introduction:</b> Detailed profiles of inpatient physical activity (PA) and sedentary behaviour (SB) are lacking for admissions with acute exacerbations (AE) chronic respiratory diseases (CRD). We collected this data as part the REACH trial (Greening et al 2014). <b>Aims:</b> To profile PA SB patients hospitalised an AE CRD. <b>Methods:</b> 248 (70.3±9.6yrs, 143 females, BMI 26.7±7.0, FEV<sub>1</sub> 1.2±0.6L, FEV<sub>1</sub>%predicted 55.5±23.8%) were recruited ≤48 hours into admission....