Rachael A. Evans
A5068587473- Chronic Obstructive Pulmonary Disease (COPD) Research
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Cardiovascular and exercise physiology
- Intensive Care Unit Cognitive Disorders
- COVID-19 and Mental Health
- Cardiac Health and Mental Health
- Chronic Disease Management Strategies
- Asthma and respiratory diseases
- Delphi Technique in Research
- Advanced Surface Polishing Techniques
- Respiratory and Cough-Related Research
- COVID-19 and healthcare impacts
- Thermal Regulation in Medicine
- Advanced machining processes and optimization
- Frailty in Older Adults
- Occupational Health and Performance
- Physical Activity and Health
- Heart Rate Variability and Autonomic Control
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health and Wellbeing Research
- SARS-CoV-2 and COVID-19 Research
- Obstructive Sleep Apnea Research
- Cystic Fibrosis Research Advances
University Hospitals of Leicester NHS Trust
2016-2025
Glenfield Hospital
2016-2025
University of Leicester
2016-2025
NIHR Leicester Biomedical Research Centre
2015-2025
National Institute for Health Research
2018-2025
University College London
1988-2025
Northern Hospital
2025
Nerve Centre
2018-2025
Noah's Ark Children's Hospital for Wales
2024
Oxford University Hospitals NHS Trust
2013-2024
The impact of COVID-19 on physical and mental health employment after hospitalisation with acute disease is not well understood. aim this study was to determine the effects COVID-19-related employment, identify factors associated recovery, describe recovery phenotypes. Post-hospitalisation (PHOSP-COVID) a multicentre, long-term follow-up adults (aged ≥18 years) discharged from hospital in UK clinical diagnosis COVID-19, involving an assessment between 2 7 months discharge, including detailed...
No effective pharmacological or non-pharmacological interventions exist for patients with long COVID. We aimed to describe recovery 1 year after hospital discharge COVID-19, identify factors associated patient-perceived recovery, and potential therapeutic targets by describing the underlying inflammatory profiles of previously described clusters at 5 months discharge.
The incremental shuttle walking test (ISWT) is used to assess exercise capacity in patients with chronic obstructive pulmonary disease (COPD) and employed as an outcome measure for rehabilitation. This study was designed establish the minimum clinically important difference ISWT.372 (205 men) performed ISWT before after a 7-week outpatient rehabilitation programme. After completing course, subjects were asked identify, from 5-point Likert scale, perceived change their performance immediately...
Ziauddeen N, Gurdasani D, O’Hara ME, et al. Characteristics of long covid: findings from a social media survey.medRxiv2021 [Preprint] doi:10.1136/jech-2021-SSMabstracts.194.
Immunocompromised individuals are not optimally protected by COVID-19 vaccines and potentially require additional preventive interventions to mitigate the risk of severe COVID-19. We aimed characterise describe across immunocompromised groups as pandemic began transition an endemic phase.
The longitudinal trajectories of cardiopulmonary abnormalities and symptoms following infection with coronavirus disease (COVID-19) are unclear. We sought to describe their natural history in previously hospitalised patients, compare this controls, assess the relationship between impairment at 6 months post-COVID-19.
Rationale: Shared symptoms and genetic architecture between coronavirus disease (COVID-19) lung fibrosis suggest severe acute respiratory syndrome 2 (SARS-CoV-2) infection may lead to progressive damage. Objectives: The UK Interstitial Lung Disease Consortium (UKILD) post–COVID-19 study interim analysis was planned estimate the prevalence of residual abnormalities in people hospitalized with COVID-19 on basis risk strata. Methods: PHOSP–COVID-19 (Post-Hospitalization COVID-19) used capture...
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective and subjective components. They common debilitating, can affect the ability to work, yet their biological underpinnings remain unknown. In this prospective cohort study of 1,837 adults hospitalized COVID-19, we identified two distinct biomarker profiles measured during acute admission, which predict outcomes 6 12 months after COVID-19. A first profile links elevated fibrinogen relative...
One in ten severe acute respiratory syndrome coronavirus 2 infections result prolonged symptoms termed long disease (COVID), yet phenotypes and mechanisms are poorly understood
The impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and associated "lockdown" measures on exacerbations chronic obstructive pulmonary disease (AECOPD) is unknown. We aimed to evaluate change in AECOPD treatment frequency during first 6 weeks lockdown UK compared with 2019 assess changes self-reported behaviour wellbeing.
Background The impact of COVID-19 on physical and mental health, employment following hospitalisation is poorly understood. Methods PHOSP-COVID a multi-centre, UK, observational study adults discharged from hospital with clinical diagnosis involving an assessment between two- seven-months later including detailed symptom, physiological biochemical testing. Multivariable logistic regression was performed for patient-perceived recovery age, sex, ethnicity, body mass index (BMI),...
Abstract Background Identifying clusters of multiple long-term conditions (MLTCs), also known as multimorbidity, and their associated burden may facilitate the development effective cost-effective targeted healthcare strategies. This study aimed to identify MLTCs associations with health-related quality life (HRQoL) in two UK population-based cohorts. Methods Age-stratified were identified at baseline Biobank ( n = 502,363, 54.6% female) UKHLS 49,186, 54.8% using latent class analysis (LCA)....
Post-COVID syndrome involves prolonged symptoms with multi-system and functional impairment lasting at least 12 weeks after acute COVID-19. We aimed to determine the efficacy of exercise-based rehabilitation interventions, either face-to-face or remote, compared usual care in individuals experiencing following a hospitalisation This single-blind randomised controlled trial two COVID interventions (face-to-face remote) participants hospitalisation. The were remote eight-week program...