- Probiotics and Fermented Foods
- Gut microbiota and health
- Virology and Viral Diseases
- Neuroscience of respiration and sleep
- Rabies epidemiology and control
- Virus-based gene therapy research
- Human-Animal Interaction Studies
- Herpesvirus Infections and Treatments
- Toxoplasma gondii Research Studies
- Viral gastroenteritis research and epidemiology
- Infant Nutrition and Health
- Infectious Encephalopathies and Encephalitis
- Milk Quality and Mastitis in Dairy Cows
- Sleep and Wakefulness Research
- Neuroscience and Neuropharmacology Research
- Neonatal and fetal brain pathology
- Veterinary Orthopedics and Neurology
- Animal health and immunology
- Viral Infections and Vectors
- Neural dynamics and brain function
- Glycogen Storage Diseases and Myoclonus
- Dermatological diseases and infestations
- Helminth infection and control
- Infant Health and Development
- Parasitic Infections and Diagnostics
Universidad de la República
2007-2024
Instituto de Investigaciones Biológicas Clemente Estable
2014
Universidad La República
2010
Observatorio Astronómico Los Molinos
2009
ABSTRACT Background Familial narcolepsy in dogs has been associated with mutations the HCRTR2 gene Labrador retrievers, dachshunds, and Doberman pinschers, causal mutation differing between breeds. Objective To characterize genetic responsible for familial Dogo Argentino dogs. Animals Ten dogs, three narcoleptic seven clinically normal, of which four were related unrelated to Methods Case control prospective study. DNA was extracted from blood samples all Whole‐genome sequencing performed on...
We examined the cerebellum and cerebrum of 4 vaccinated dogs, 3–60-mo-old, that displayed clinical signs canine distemper virus (CDV) infection, died 7–40 d after developing neurologic signs. The main histologic lesions were demyelination, gliosis, meningitis, perivascular lymphocytic cuffing, inclusion bodies. These similar in all cases regardless time since vaccination, except meningoencephalitis gliosis subacute 3 dogs chronic 1 dog. However, these differences did not appear to be related...
For the conclusive diagnosis of Cushing's Syndrome, a stimulating ACTH test or low suppressive Dexamethasone is used. Reports in other species than dog indicate that plasma cortisol concentration after administration affected by gender. We investigated effect gender on response to and tests dogs.Seven healthy adult Cocker Spaniels (4 females 3 males) were assigned two factorial design: 4 dogs (2 2 received IV 0.01 mg/kg, while an saline solution (control group). Two weeks later treatments...
Five of 16 cats belonging to the same owner were brought veterinary hospital because a 30-day history signs intense pruritus and alopecic erythematous areas with bloody crusts. Notoedric mange was diagnosed confirmed by microscopic examination skin scrapings all 5 cats. The remaining did not have clinical mange, Notoedres cati observed after scrapings. A decision made treat doramectin subcutaneously. In each cat, 0.1 ml 1% solution administered s.c. Body weights ranged from 2.9 7.1 kg (6.4...
Canine distemper (CD) is a deadly, multi-system infection caused by Morbillivirus. The Distemper Virus (CDV) frequently affects the nervous system with demyelinating leukoenceph-alitis, most common neurological manifestation. disease has been linked to multiple sclerosis (MS) in humans due similar clinical presentation and pathophysiological mecha-nisms. In MS, visual evoked potentials (VEP) have identified as reliable marker for progression, enabling early detection of clinically suspected...
The purpose of this study was to examine the relationship between demyelination and glial cell responses in cerebellum CDV-infected dogs. We subdivided disease staging by adding degree determined LFB staining previously reported from acute stage chronic stage, investigated number histological changes astroglia, microglia Purkinje cells each stage. Reactions astrocytes were observed at an early when not evident. Changes progressed with demyelination. Demyelination initially began medulla...
The purpose of this study was to examine the relationship between demyelination and cellular reactions in cerebellum Canine Distemper Virus (CDV)-infected dogs. We subdivided disease staging by adding degree determined Luxol Fast Blue staining previously reported from acute stage chronic stage, investigated number histological changes astroglia, microglia, Purkinje cells each stage. Reactions astrocytes microglia were observed at an early when not evident. Changes progressed with...
Canine distemper (CD) is a deadly, multi-system infection caused by Morbillivirus. The canine virus (CDV) frequently affects the nervous system with demyelinating leukoencephalitis, most common neurological lesion. disease has been linked to multiple sclerosis (MS) in humans due similar clinical presentation and pathophysiological mechanisms. In MS, visual evoked potentials (VEPs) have identified as reliable marker for progression, enabling early detection of clinically suspected lesions....
Congenital hydrocephalus is a neurological disorder frequently observed in dogs. It characterised by an increase of cerebrospinal fluid volume the ventricular system that can cause atrophy brain tissue. be provoked diverse causes, as it idiopathic or secondary to nervous abnormalities. Diagnosis based on clinical signs and imaging studies, but neurophysiological techniques provide valuable information. This report describes functional changes brainstem evaluated electroencephalogram auditory...