Aging is considered one of the major risk factors for several human disorders. The telomere plays a crucial role in regulating cellular responsiveness to stress and growth stimuli as well maintaining integrity Deoxyribonucleic Acid (DNA), aging leads progressive decline length (TL) due continuous cell division. aim this study was determine relationship between TL advancing age impact metabolic syndrome (MetS) on TL. Firstly, we determined association TL, by measuring (T/S ratio) healthy...

From Volume 20 (2006), this title is published by Society of Integrated Sciences (International Medart, PO Box 37, 814 99 Bratislava 1, Slovak Republic, E-mail: publisher@nel.edu, Fax: +41 13553207).

Introduction The coronavirus disease 2019 (COVID-19) vaccination has been suggested for those with comorbidities, although there are concerns regarding the vaccine's safety. This study aimed to compare severity and incidence of post-vaccination side effects in people without comorbidities. Another aim this was also look effect multimorbidity on adverse events. Methods observational conducted from November 2021 February 2022. Data were collected all over Pakistan using a self-administered...

To investigate the changes in levels of C-reactive protein (CRP) and hematological parameters among smokeless tobacco (SLT) users.A comparative cross-sectional study was conducted at community level coastal districts Sindh province namely Badin, Thatta, Sujawal from January 2017 to December 2019. The CRP were evaluated by well-established methods SLT non-SLT users.There a statistically significant difference between users (mean = 0.77) versus non-users 0.18), p <0.001. Among parameters,...

Introduction: Drug-related problems (DRPs) pose significant challenges in healthcare, often leading to ineffective medication use and adverse outcomes. This study aimed assess the incidence types of DRPs at a teaching hospital Pakistan while evaluating acceptance pharmaceutical interventions by medical team. Factors contributing include polypharmacy, chronic diseases, errors, with associated increased morbidity, mortality, healthcare costs. Methodology: A cross-sectional was conducted...

Background: Self-medication is a globally prevalent practice, with varying degrees of awareness and regulation across different regions. In developing countries like Pakistan, the practice poses significant public health challenges, including risk medication misuse antibiotic resistance. Jamshoro, city diverse demographic educational landscape, provides unique setting to explore knowledge, attitudes, practices self-medication among its residents. Objective: This study aimed assess extent...

Background: A captivating smile is the epitome of aesthetic dentistry, heavily reliant on meticulous shade matching with natural teeth. However, achieving optimal necessitates a profound understanding various factors influencing tooth color perception and intricacies selection methods. This study aims to determine predominant shades within Hyderabad, Sindh population, shedding light distribution trends across different age groups genders. The primary goal equip local dentists data-driven...

Background: Speech and language disorders in young children can have substantial impacts on their social, emotional, behavioral, cognitive development. Understanding the prevalence risk factors associated with these is crucial for early intervention effective treatment strategies. Objective: This study aimed to assess of speech presenting a Pediatric Rehabilitation Ward, identify demographic socioeconomic characteristics conditions, evaluate therapy patterns utilized management. Methods: An...

Background: Psoriasis is a chronic inflammatory skin disorder with complex pathophysiology involving wide array of immune responses. The Histamine H4 Receptor (H4R) has been identified as potential mediator in responses, its role psoriasis yet to be fully elucidated. This study investigates the expression levels Human Gene (HRH4) patients Sindh, Pakistan, aiming understand association disease status, severity, and treatment history. Methods: cross-sectional was conducted across multiple...

The undertaken study is based on stylistic analysis of Ahmed Ali’s short story Our Lane. analyzes how the author has used linguistic features like noun, adjective, conjunction, sentence complexity to portray social, political, economic, religious, psychological and cultural conditions colonized natives Indian subcontinent in wake British colonial rule. portrays rule deteriorated people socially, economically, politically psychologically. use adjective consonant with established norm using 7...

Objectives: In elderly patients, recent research has also questioned the effectiveness of this surgery. The objective our study is to evaluate safety and applicability laparoscopic cholecsytectomy in geriatric patients (over 60 year age) for symptomatic cholelothiasis. Study Design: Prospective observational study. Setting: Different surgical wards at LUHMS Jamshoro / Hyderabad who undergone cholecystectomy. Period: One from 01-03-2017 28-02-2018. Material &amp; Methods: 100 years age above...

Introduction: Coronavirus Disease 2019 (COVID-19) is a cluster of acute respiratory illnesses with unknown etiology, which firstly appeared in Wuhan, Hubei Province, China, December 2019. All educational institutes Pakistan were completely closed from March 13, 2020, to August 15, 2020. This condition disturbs the daily routines children mental health needs. sudden closure limited their physical activities routine life. study aims observe depression associated COVID-19 and its impact on...

Background: prolonged bloating, abdominal discomfort, reflux, nausea, vomiting, diarrhea, stomach pain, and discomfort characterize a collection of digestive conditions known as gastric distress. Proton pump inhibitors (PPIs) remain the superior choice worldwide in antisecretory therapy evidence-based treatment upper gastrointestinal disorders including gastroesophageal reflux disease, erosive esophagitis, dyspepsia peptic ulcer disease. Methods: To digest materials, 2:1 ratio HNO3 (65%)...

It is of interest to document the serum prolactin levels among thyroid associated cancer patients in Summon area Sindh Pakistan. Hence, we inspected 20 cancer-positive hailstones locales and East Asia assessed linked chemical blood. Blood samples are gathered for hormonal profile like prolactin, free T4 (FT4) luteinizing compound (LH), T3 (FT3), follicle-stimulating hormone (FSH). Moreover, estimation organ extent was also completed population. Data shows critical contrast degree positive...

BACKGROUND: Ninety-five millions of Pakistan's 161 million people, roughly 60% population live in malaria endemic regions.Despite a well-established control programme, 500,000 infections and 50,000 malaria-attributable deaths occur each year Pakistan.In Pakistan 15% lives high transmission area, 84% low 1% free with 64% vivax 36% Falciparum infections.OBJECTIVE: The objective this study was to assess the therapeutic efficacy safety Dihydroartemisinin-piperaquine (DP) for treatment...

From Volume 20 (2006), this title is published by Society of Integrated Sciences (International Medart, PO Box 37, 814 99 Bratislava 1, Slovak Republic, E-mail: publisher@nel.edu, Fax: +41 13553207).

Aim: To determine the socioeconomic and demographic characteristics that influence raw alcohol intake. Methods: It was a cross sectional study, conducted at community level Badin district for 3 months from 1st September 2019 to 30th November 2019. The study included all of cases met inclusion criteria. All responders or their relatives provided written consent. A complete history intake associated factors obtained. Performa used record data. For data analysis, SPSS v.22 utilized. Results:...

To estimate the effectiveness of sodium perborate with carbamide-peroxide (urea peroxide) to remove staining non-vital discolored teeth. Comparative cross sectional study. Dental department operative dentistry, LUMHS, Jamshoro Sindh, Pakistan, from December 15-12-2014 June 15-6-2015. A total 160 single rooted teeth intact clinical crowns have been collected. Using human blood, were discolored. With vita shade guide, shades taken. Each tooth was handled root canal. 2 mm root-canal-filling...

Aims: To determine the pattern of chewable tobacco habits, to assess oral hygiene habits among patients visiting dental OPD and association health maintenance with severity periodontal disease.&#x0D; Study Design: It was a comparative cross sectional study.&#x0D; Place Duration Study: Dental Outpatient Department, Liaquat University Hospital Hyderabad Jamshoro for six months from 1st February 2020 31st July 2020.&#x0D; Methodology: A total 362 subjects were selected by non-probability...