A5101578903- Anesthesia and Neurotoxicity Research
- Cardiac Ischemia and Reperfusion
- Eicosanoids and Hypertension Pharmacology
- Pain Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Anesthesia and Sedative Agents
- Neonatal Respiratory Health Research
- Intensive Care Unit Cognitive Disorders
- Sleep and Wakefulness Research
- Healthcare and Venom Research
- Ion channel regulation and function
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mitochondrial Function and Pathology
- Traumatic Brain Injury and Neurovascular Disturbances
- Innovations in Medical Education
- Enhanced Recovery After Surgery
- High Altitude and Hypoxia
- Cardiac Arrhythmias and Treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Pharmacological Effects of Natural Compounds
- Cardiac Arrest and Resuscitation
- Vagus Nerve Stimulation Research
- Neonatal and fetal brain pathology
Army Medical University
2010-2019
Xinqiao Hospital
2009-2019
Army Medical College
2019
General Hospital of Guangzhou Military Command
2010
Wuhan General Hospital of Guangzhou
2010
Chongqing Three Gorges Central Hospital
2010
Daping Hospital
2009
First Affiliated Hospital of Jiangxi Medical College
1994
International Space Science Institute - Beijing
1992
Mount Sinai Hospital
1990
Several medical conditions exhibit age- and sex-based differences. Whether or not traumatic shock exhibits such differences with regard to vascular responsiveness is clear. In a cohort of 177 healthy subjects 842 trauma patients (21–82 years) as well different ages (4, 8, 10, 14, 18, 24 wk; 1 1.5 sexes Sprague-Dawley normal rats, the underlying mechanisms were investigated. Middle-aged young women female rats reproductive age had higher in condition lower decrease after than older men male...
Abstract Background Biomarkers released from the heart at early stage of ischemia are very important to diagnosis ischemic disease and salvage myocytes death. Known specific markers for blood tests including CK-MB, cardiac troponin T (cTnT) I (cTnI) after onset significant necrosis instead ischemia. Thus, they not good biomarkers diagnose myocardial injury before happens. Therefore, in this study, we performed proteomic analysis on effluents perfused human hearts donors different time....
Propofol is a widely used anesthetic in the clinic while several studies have demonstrated that propofol exposure may cause neurotoxicity developing brain. However, effects of early on cerebellar development are not well understood. (30 or 60 mg/kg) was administered to mice postnatal day (P)7; Purkinje cell dendritogenesis and Bergmann glial were evaluated P8, granule neuron migration analyzed P10. The results indicated P7 resulted significant reduction calbindin-labeled cells their dendrite...
Peripheral nerve injury-caused hyperexcitability and abnormal ectopic discharges in the primary sensory neurons of dorsal root ganglion (DRG) play a key role neuropathic pain development maintenance. The two-pore domain background potassium (K 2P ) channels have been identified as determinants resting membrane potential neuronal excitability. However, whether K contribute to is still elusive. We reported here that 1.1, first mammalian channel, was highly expressed mouse DRG distributed...
To summarize our experience in the anesthetic management of conjoined twins undergoing one-stage surgical separation.Medical records admitted to hospital for treatment and considered separation from 1996 present were retrospectively reviewed. Four cases underwent under general anesthesia. Preoperative evaluation was performed determine extent anatomical conjunction associated anomalies. Anesthesia simultaneously induced all twins. The intubation procedure successfully with head slightly...
This study aimed to investigate the effects of mitochondrial ATP-sensitive potassium (MitoK ATP ) channel opening on translocation protein kinase C epsilon (PKCε).In addition, we determine relationship between PKCε and production reactive oxygen species (ROS).PKCε expression in cultured adult rat ventricular myocytes was investigated by immunofluorescence Western blotting.Diazoxide (DZ), a selective MitoK activator, caused significant myofibrillar-like structures...
Article COMPARATIVE PROTEOMICS ANALYSIS OF DIFFERENTIALLY EXPRESSED PHOSPHOPROTEINS IN ADULT RAT VENTRICULAR MYOCYTES SUBJECTED TO DIAZOXIDE PRECONDITIONING was published on June 1, 2006 in the journal Drug Metabolism and Personalized Therapy (volume 21, issue 3-4).
Airway management in the patients who receive transmaxillary approach for resection of giant pituitary tumor presents a clinical challenge to anesthesiologists. Oral or nasal route tracheal intubation can interfere with surgical procedures. This report describes submental airway patient underwent recurrent via approach. Submental is an adaptable and safe alternative technology during operation.
The influence of isoflurane (Iso) on the synthesis and secretion phosphatidylcholine (PC) alveolar type II cells (AT cells) injured by hydrogen peroxide (H2O2) was investigated. After primary culturing for 32 h, AT isolated purified from adult Sprague-Dawley rats were randomly divided into six groups: control group, 02.8 mM Iso 2.8 75 microM H2O2 + 0.28 H202 group. Synthesis detected 3H-choline chloride incorporation. It found that significantly reduced PC compared with group (p <0.05, p...
The influence of isoflurane (Iso) on proliferation and Na+,K+-ATPase activity alveolar type II cells (ATII cells) injured by hydrogen peroxide (H2O2) was investigated. ATII isolated purified from adult Sprague-Dawley rats were randomly divided into six groups: control group, 0.28 mM Iso 2.8 75 microM H2O2 + group. After primary culture for 32 hours, the detected MTT assay, after 24 hours lactate dehydrogenase (LDH) in cells, malonaldehyde (MDA) content medium, measured colorimetry. It found...
We determined the effects of changing spatial dispersion acetylcholine release on phase-dependent chronotropic responses to vagal stimulation in anesthetized dogs. stimulated vagus nerves with one brief burst electrical pulses each cardiac cycle, and we changed timing stimulus by a small, constant amount cycle scan entire cycle. To vary heterogeneity release, voltage over range submaximal values. achieve maximum homogeneity used supramaximal voltages, varied level from excited fiber number...
Preoperative oral carbohydrates has been suggested to attenuate insulin resistance and decrease postoperative complications. In this study, a vitamin-rich carbohydrate beverage was administered before surgery in an animal model investigate its effects on the surgical stress response S-100β levels. Thirty aged male Sprague-Dawley rats were randomly assigned three groups: control group (n = 6), fasting 12), carbohydrate-treated (CHO group, n 12). Rats not given any treatment. received...
The influence of isoflurane (Iso) on the synthesis surfactant-related protein A (SP-A) alveolar type II (AT II) cells in primary culture and after injury by H2O2 was investigated. AT were isolated purified from adult Sprague-Dawley rats used for experiments 32 h culture. cell cultures randomized to six groups (n = 8 each group): control group (no treatment), 0.28 mM Iso group, 2.8 75 microM + group. Each continuously incubated 3 administration and/or H2O2. intracellular SP-A medium measured...