A5060563083- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Medical Imaging Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Lanthanide and Transition Metal Complexes
- Vascular Malformations Diagnosis and Treatment
- Marine animal studies overview
- Intracranial Aneurysms: Treatment and Complications
- Advanced Radiotherapy Techniques
- Island Studies and Pacific Affairs
- Radiomics and Machine Learning in Medical Imaging
- Traumatic Brain Injury and Neurovascular Disturbances
- Atomic and Subatomic Physics Research
- Cerebrovascular and Carotid Artery Diseases
- Pacific and Southeast Asian Studies
- Radiation Therapy and Dosimetry
Institute of Cancer Research
2014-2021
University Health Network
2021
Princess Margaret Cancer Centre
2021
Engineering and Physical Sciences Research Council
2015
Sheffield Teaching Hospitals NHS Foundation Trust
2009-2010
Royal Hallamshire Hospital
2008-2009
University of Sheffield
2009
The purpose of this work was to assess the reproducibility diffusion imaging, and in particular apparent coefficient (ADC), intra-voxel incoherent motion (IVIM) parameters tensor imaging (DTI) parameters, across multiple centres using clinically available protocols with limited harmonization between sequences. An ice-water phantom nine healthy volunteers were scanned fives on eight scanners (four Siemens 1.5T, four Philips 3T). mean ADC, IVIM (diffusion D perfusion fraction f) DTI (mean...
The volumetric flow rate (VFR) waveform over the cardiac cycle in cerebral vasculature is a significant factor many studies, which involve cerebrovascular function. Perhaps contrary to expectation, literature this area sparse and characteristics of blood waveforms are ill defined. A better understanding variation pulsatility may aid our knowledge risk factors involved diseases conditions, such as stroke, arteriovenous malformation, or aneurysm rupture. This study sought characterise at...
Stereotactic Gamma Knife radiosurgery utilizes ionizing beams from (60)Co sources and relies on a combination of collimator sizes, weighting, etc to generate high-dose region that is conformal with designated target volume. Dose computation typically performed by computer, but in this paper, single dose profile behaviour modelled analytically then extended accommodate multiple collimators different weights co-located isocentres. The helmet derived top-hat beam approximation an idealized...
Geoarchaeological investigations of limestone caves along the Rove Peninsula, where several Lapita-era (1150-750 BC) sites dating from earliest period Fiji?s human history have been found, was undertaken by a team University South Pacific and Fiji Museum. Surface collection excavation in largest cave – Qaranibourewa hindered large amounts ceiling collapse no trace occupation earlier than about AD 1000 found. The second-largest ? Qaramatatolu had fill 190 cm thick but this determined to be...
To investigate the feasibility of accurately quantifying concentration MRI contrast agent in flowing blood by measuring its T1 a large vessel. Such measures are often used to obtain patient-specific arterial input functions for accurate fitting pharmacokinetic models dynamic enhanced data. Flow is known produce errors with this technique, but these have so far been poorly quantified and characterised context pulsatile flow rapidly changing as would be expected vivo.A phantom was developed...
Purpose: To assess the feasibility of accurately quantifying concentration MRI contrast agent (CA) in pulsatile flowing blood by measuring its T 1 , as is common for purposes obtaining a patientspecific arterial input function (AIF). Dynamic enhanced (DCE) – and pharmacokinetic (PK) modelling widely used to produce measures vascular but accurate measurement AIF undermines their accuracy. A proposed solution measure large vessel using Fram double flip angle method during passage bolus CA....