A5077529015- Regulation of Appetite and Obesity
- Biochemical Analysis and Sensing Techniques
- Neuropeptides and Animal Physiology
- Adipokines, Inflammation, and Metabolic Diseases
- Eating Disorders and Behaviors
- Stress Responses and Cortisol
- Adipose Tissue and Metabolism
- Neuroendocrine regulation and behavior
- Obsessive-Compulsive Spectrum Disorders
- Neurobiology and Insect Physiology Research
- Spaceflight effects on biology
- Child Nutrition and Feeding Issues
- Hypothalamic control of reproductive hormones
- Plant Reproductive Biology
- Hormonal Regulation and Hypertension
- Dermatology and Skin Diseases
- Receptor Mechanisms and Signaling
- Pregnancy and Medication Impact
- Apelin-related biomedical research
- Gastrointestinal motility and disorders
- Cardiovascular Issues in Pregnancy
- Biochemical effects in animals
- Dietary Effects on Health
- Music Therapy and Health
- Circadian rhythm and melatonin
Humboldt-Universität zu Berlin
2017-2023
Charité - Universitätsmedizin Berlin
2017-2023
Freie Universität Berlin
2017-2023
Helios Kliniken
2023
The University of Adelaide
2018
University of Wisconsin–La Crosse
2018
Due to phoenixin's role in restraint stress and glucocorticoid stress, as well its recently shown effects on the inflammasome, we aimed investigate of lipopolysaccharide (LPS)-induced inflammatory activity brain nuclei-expressing phoenixin. Male Sprague Dawley rats (n = 6/group) were intraperitoneally injected with either LPS or control (saline). Brains processed for c-Fos phoenixin immunohistochemistry resulting slides evaluated using ImageJ software. was counted densitometry. significantly...
Nesfatin-1 is a well-established anorexigenic peptide. Recent studies indicated an association between nesfatin-1 and anxiety/depression-like behavior. However, it unclear whether this effect retained in obesity. The aim was to investigate the of nesfatin-130-59—the active core nesfatin-1—on anxiety depression-like behavior normal weight (NW) diet-induced (DIO) obese rats. Male rats were intracerebroventricularly (ICV) cannulated received nesfatin-130-59 (0.1, 0.3, or 0.9 nmol/rat) vehicle...
The prevalence and incidence of depressive disorders are rising worldwide, affecting about 322 million individuals, underlining the need for behavioral studies in animal models. In this protocol, to study depression-like anhedonic behavior rats, established sucrose preference novelty-induced hypophagia tests combined with an automated food liquid intake monitoring system. Prior testing, paradigm, male rats trained at least 2 days consume a solution addition tap water. During test, again...
Phoenixin-14 is a recently discovered peptide regulating appetite. Interestingly, it expressed in the gastrointestinal tract; however, its supposed receptor, GPR173, predominantly found hypothalamic areas. To date, unknown how peripherally secreted phoenixin-14 able to reach centrally located receptor. investigate whether phoenixin pass blood-brain barrier, we used an vitro mono-culture barrier (BBB) model consisting of brain capillary-like endothelial cells derived from human...
Objective : The upper esophageal sphincter (UES) prevents regurgitation of contents into the larynx and pharynx.UES pressures decrease during sleep increase apneic events.Little is known about UES function in other physiologic states.We sought to measure changes with rest exercise different phases respiration.Methods Participants were >18 years old, without gastrointestinal or respiratory symptoms.High -resolution manometry topography airway, UES, thoracic esophagus performed, inspiration...
Abstract Background Gastric electrical stimulation (GES) is an effective therapy in medically refractory chronic nausea and vomiting. GES assumed to be a contraindication for pregnancy. We examined the safety of during pregnancy its clinical impact on vomiting symptoms. Methods A retrospective study was performed two tertiary centers including all female patients childbearing age implanted with GES. Patients without while were asked about their desire concerns who pregnant interviewed course...
The prevalence and incidence of depressive disorders are rising worldwide, affecting about 322 million individuals, underlining the need for behavioral studies in animal models. In this protocol, to study depression-like anhedonic behavior rats, established sucrose preference novelty-induced hypophagia tests combined with an automated food liquid intake monitoring system. Prior testing, paradigm, male rats trained at least 2 days consume a solution addition tap water. During test, again...