A5029790043- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Meningioma and schwannoma management
- Radiomics and Machine Learning in Medical Imaging
- Vascular Malformations Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Management of metastatic bone disease
- Nanoplatforms for cancer theranostics
- CNS Lymphoma Diagnosis and Treatment
- MRI in cancer diagnosis
- Spine and Intervertebral Disc Pathology
- Neurological disorders and treatments
- Artificial Intelligence in Healthcare and Education
- Breast Lesions and Carcinomas
- Advanced Radiotherapy Techniques
- Lanthanide and Transition Metal Complexes
- Genetic Neurodegenerative Diseases
- Cancer Research and Treatments
- Spinal Fractures and Fixation Techniques
- Advanced MRI Techniques and Applications
- Cancer, Hypoxia, and Metabolism
- BRCA gene mutations in cancer
- Surgical site infection prevention
- Botulinum Toxin and Related Neurological Disorders
- Sarcoma Diagnosis and Treatment
Roswell Park Comprehensive Cancer Center
2023-2025
Jacobs Institute
2024
Kaleida Health
2023
University at Buffalo, State University of New York
2023
Instituto Estadual do Cérebro Paulo Niemeyer
2017
Glioblastoma (GBM) is the most common central nervous system malignancy in adults. Despite decades of developments surgical management, radiation treatment, chemotherapy, and tumor treating field therapy, GBM remains an ultimately fatal disease. There currently no definitive standard care for patients with recurrent glioblastoma (rGBM) following failure initial management.
BACKGROUND Implementing the thermoplastic mask as a treatment option in Gamma Knife radiosurgery (GKRS) has madethe discussion of relative benefits frame- or mask-based fixation for frequent occurence. Based on case review, authors discuss factors that need to be understood and considered by treating team. OBSERVATIONS The describe an 81-year-old patient with pleomorphic dermal sarcoma extended infiltrated dura mater, who underwent extensive resection requiring skin flap. Adjuvant GKRS was...
Radiation oncology relies on computer software for digital processing and planning. Artificial intelligence (AI) employs algorithms to perform tasks including pattern recognition, decision making problem solving [1]. AI has the potential impact quality of radiotherapy cancer patients [2].
Pallidal stimulation has been the usual surgical treatment for dystonia in last decades. The continuous investigation of physiopathology and motor pathways involved leads to search complementary targets improve results. authors present case a 37-year-old woman who had suffered from idiopathic hemidystonia with hyperkinetic hypokinetic movements 11 years, was treated deep brain stimulation. A brief literature review is also provided. globus pallidus internus ventral intermediate/ventral oral...
<title>Abstract</title> <bold>Purpose:</bold> The differentiation between adverse radiation effects (ARE) and tumor recurrence or progression (TRP) is a major decision-making point in the follow-up of patients with brain tumors. advent immunotherapy, targeted therapy radiosurgery has made this distinction difficult to achieve several clinical situations. Contrast clearance analysis (CCA) useful technique that can inform decisions but so far only been histologically validated context...
Spine stereotactic body radiation therapy (SBRT) for the treatment of metastatic disease is increasingly utilized owing to improved pain and local control over conventional regimens. Vertebral collapse (VBC) an important toxicity following spine SBRT. We investigated our institutional experience with SBRT as it relates VBC spinal instability neoplastic score (SINS).
Abstract PURPOSE Adverse radiation effects (ARE) including pseudoprogression are known toxicities associated with for intracranial lesions. ARE often difficult to differentiate from tumor progression. Delay in identification of progression or misidentification as can lead impact patient survival. In this study, we demonstrate the utility Contrast Clearance Analysis® (CCA) differentiating and CCA-guided decision making on METHODS Fifty-seven consecutive patients who had been diagnosed brain...
Abstract BACKGROUND Stereotactic radiosurgery (SRS) has become a standard modality in the treatment of brain metastases. The differentiation between adverse radiation effects (ARE) and tumor recurrence or progression is important this setting. advent immunotherapy targeted therapy often makes distinction difficult to achieve. Contrast clearance analysis (CCA) useful technique that can inform clinical decisions but so far only been histologically validated context high-grade gliomas. METHODS...
Abstract Trigeminal schwannomas (TS) represent 0.8 to 5% of intracranial schwannomas. Due their localization, surgery has a high morbidity, with stereotactic radiosurgery being frequent method treatment control rate. The main side effects due radiation are pseudoprogression and worsening the symptoms related affected nerve. Despite tumor necrosis, they tend be progressive, small, spread throughout tumor. We present rare case 48-year-old woman trigeminal schwannoma who underwent gamma knife...
e14061 Background: Primary or systemic high-grade B-cell lymphoma with secondary central nervous system (PCNSL SCNSL) are currently treated high-dose methotrexate (HD-MTx) based chemo-immunotherapy regimens with/without whole brain radiation therapy (WBRT). CNS relapse can occur in up to 50% of patients PCNSL SCNSL. WBRT has been used as a salvage for those patients. However, long-term neurological toxicities significantly reduce its clinical benefit. Stereotactic radiosurgery (SRS) is the...
Abstract Glioblastoma is the most common central nervous system malignancy in adults and remains a uniformly fatal disease despite two decades of developments surgical management, radiation treatment, chemotherapy, immunotherapy. There currently no established standard care for patients with recurrent glioblastoma following failure initial Stupp protocol management. In this retrospective cohort study, we set out to determine if use bevacizumab and/or Gamma Knife radiosurgery could have an...
Abstract Introduction Glioblastoma (GBM) is the most common central nervous system malignancy in adults. Despite decades of developments surgical management, radiation treatment, chemotherapy, and tumor treating field therapy, GBM remains an ultimately fatal disease. There currently no definitive standard care for patients with recurrent glioblastoma (rGBM) following failure initial management. Objective In this retrospective cohort study, we set out to examine relative effects bevacizumab...