A5101839713- Traumatic Brain Injury and Neurovascular Disturbances
- Catalytic Processes in Materials Science
- Cardiovascular Function and Risk Factors
- Atherosclerosis and Cardiovascular Diseases
- Aldose Reductase and Taurine
- Lipoproteins and Cardiovascular Health
- Plant Gene Expression Analysis
- Plant biochemistry and biosynthesis
- Heart Rate Variability and Autonomic Control
- Advanced Photocatalysis Techniques
- Blood Pressure and Hypertension Studies
- Catalysis and Oxidation Reactions
- Cancer-related molecular mechanisms research
- Effects and risks of endocrine disrupting chemicals
- Cancer, Hypoxia, and Metabolism
- Cardiovascular Health and Disease Prevention
- Hip and Femur Fractures
- TiO2 Photocatalysis and Solar Cells
- Electrocatalysts for Energy Conversion
- Orthopedic Surgery and Rehabilitation
- Cardiac Fibrosis and Remodeling
- Heavy Metal Exposure and Toxicity
- Cardiovascular Disease and Adiposity
- Hormonal Regulation and Hypertension
- Birth, Development, and Health
The First Affiliated Hospital, Sun Yat-sen University
2013-2024
Sun Yat-sen University
2014-2024
Quanzhou Institute of Equipment Manufacturing Haixi Institute
2024
Fujian Institute of Research on the Structure of Matter
2024
Chinese Academy of Sciences
2007-2024
Changzhou University
2024
Guangxi Normal University
2024
Shenzhen Luohu People's Hospital
2024
Shanghai Ocean University
2024
Guangdong Pharmaceutical University
2024
The recent outbreak of betacoronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which is responsible for the Disease 2019 (COVID-19) global pandemic, has created great challenges in viral diagnosis. existing methods nucleic acid detection are high sensitivity and specificity, but need complex sample manipulation expensive machinery slow down disease detection. Thus, there an urgent demand to develop a rapid, inexpensive, sensitive diagnostic test aid point-of-care...
Age and obesity are dominant risk factors for several common cardiometabolic disorders, both known to impair adipose tissue function. However, the underlying cellular genetic linking aging on function have remained elusive. Adipose stem precursor cells (ASPCs) an understudied, yet crucial cell type due their deterministic adipocyte differentiation potential, which impacts capacity store fat in a metabolically healthy manner. We integrated subcutaneous (SAT) bulk (n=435) large single-nucleus...
Background The relationship between diabetes mellitus (DM) and cancer incidence has been evaluated in limited kinds of cancer. effect anti-diabetic therapy (ADT) on carcinogenesis among diabetic patients is also unclear. Materials Methods Using population-based representative insurance claims data Taiwan, 36,270 DM 145,080 comparison subjects without were identified from 2005 to 2010. association the top ten leading causes cancer-related death Taiwan was evaluated. Whether ADT altered risk...
Physical effort stimulates the reninangiotensin system (RAS). We studied effect of an angiotensin-converting enzyme inhibitor (ACE inhibitor) in a double-blind placebo-controlled study, on eight volunteers undergoing physical stress ergometric bicycle. The effects captopril (C) (50 mg, three times daily for 3 days) arterial pressure (AP), O2 consumption (VO2), variations auricular natriuretic factor (ANF), renin, angiotensin II (AII) plasma levels, as well glomerular filtration rate (GFR)...
Oxidized LDL cholesterol (ox-LDL-C) is considered to be a key factor of initiating and accelerating atherosclerosis (AS). The purpose this study elucidate the sensitivity specificity ox-LDL oxidation ratio in diagnosis coronary artery disease (CAD). For first time, we investigated ALB(ox-LDL/ALB).Blood ox-LDL, total (TC), high density lipoprotein (HDL-C), low (LDL-C), triglyceride (TG) albumin (ALB) were measured patients with acute myocardial infarction (AMI, n = 80), unstable angina...
Though glioblastoma multiforme (GBM) is the most frequently occurring brain malignancy in adults, clinical treatment still faces challenges due to poor prognoses and tumor relapses. Recently, microRNAs (miRNAs) have been extensively used with aim of developing accurate molecular therapies, because their emerging role regulation cancer-related genes. This work aims identify miRNA signatures related survival GBM patients for therapies. proposes a support vector regression (SVR)-based...
This study aimed to investigate whether cadmium induces ovarian granulosa cell damage by activating protein kinase R-like endoplasmic reticulum (PERK)-eIF2α-ATF4 through (ER) stress and elucidate the underlying regulation mechanism. Two models of exposure were established. In one model, cells isolated from 21-day-old female Sprague Dawley rats cultured in vitro for 36 h exposed CdCl2 (0, 5, 10, 20 μM), another a human tumor line (COV434) was used construct binding immunoglobulin...
<b><i>Purpose:</i></b> Lactate dehydrogenase A (LDHA), which functions as a crucial enzyme in transforming from pyruvate into lactate, has been reported to be overexpressed various advanced cancer and its silencing turned out tumor suppressive. Previous studies have showed that the expression of LDHA was higher renal cell carcinoma (RCC) than corresponding normal tissue. However, function RCC, possible mechanism progression, not investigated....