A5087776255- Acute Lymphoblastic Leukemia research
- Hematopoietic Stem Cell Transplantation
- Chronic Myeloid Leukemia Treatments
- Acute Myeloid Leukemia Research
- Renal Transplantation Outcomes and Treatments
- Diversity and Career in Medicine
- Sexual Differentiation and Disorders
- Chronic Lymphocytic Leukemia Research
- Virus-based gene therapy research
- Childhood Cancer Survivors' Quality of Life
- Biomedical Ethics and Regulation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Innovations in Medical Education
- CRISPR and Genetic Engineering
- Blood groups and transfusion
- Neutropenia and Cancer Infections
- CAR-T cell therapy research
- Autoimmune and Inflammatory Disorders Research
- Hemoglobinopathies and Related Disorders
- Transplantation: Methods and Outcomes
- Parvovirus B19 Infection Studies
- Urological Disorders and Treatments
- Healthcare professionals’ stress and burnout
- Health Systems, Economic Evaluations, Quality of Life
- Ideological and Political Education
Dana-Farber Cancer Institute
2022-2025
Dana-Farber/Boston Children's Cancer and Blood Disorders Center
2022-2024
Boston Children's Hospital
2023-2024
Harvard University
2024
Rutgers Cancer Institute of New Jersey
2022
Rutgers, The State University of New Jersey
2022
University of Chicago
2019
National Institutes of Health Clinical Center
2012-2013
Patients with congenital adrenal hyperplasia (CAH) often suffer from long-term complications secondary to chronic glucocorticoid therapy and suboptimal treatment regimens.
The gene for congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency, CYP21A2, is flanked by the encoding tenascin-X (TNXB), a connective tissue extracellular matrix protein that has been linked both autosomal dominant and recessive Ehlers-Danlos syndrome (EDS). A contiguous deletion of CYP21A2 TNXB described.The objective study was determine frequency clinical significance haploinsufficiency in CAH patients.A total 192 consecutive unrelated patients being seen as part an...
Anaplastic sarcoma of the kidney (ASK) is a DICER1-related neoplasm first identified as distinctive tumor type through evaluation unusual cases putative anaplastic Wilms tumors. Subsequent case reports presence biallelic DICER1 variants well progression from cystic nephroma, benign neoplasm. Despite increasing recognition ASK distinct entity, optimal treatment remains unclear.
Immunosuppression in solid organ transplant recipients inhibits protective immune responsiveness to pathogens and vaccines. However, specific cell states that associate with failure generate immunity are not known. Here, we perform scRNAseq CyTOF analyses of PBMC from 12 pediatric 8 healthy children revealing the full spectrum present these individuals, examine association generation humoral cellular following vaccination. We determined clonal expansion a subset CD8+ effector T cells is...
Abstract The pediatric hematology and oncology (PHO) workforce landscape has been evolving over the past decades, with concern for waning interest in subspecialty. We aimed to evaluate impact of initial PHO job search on fellow stress anxiety, addition perceptions experience potential areas improvement. An anonymous survey consisting demographics, emotional health impacts such as experiences was developed distributed program leadership at all 74 fellowship programs. At least one...
Recent American Society for Transplantation and Cellular Therapy guidelines have sought to establish clinical research expectations participants in blood marrow transplantation (BMT) cellular therapy (CT) fellowships. However, little is known about BMT/CT fellowships the value they find from this additional training. We wanted characterize demographics, motivations, experiences of recent developed a 27-item online survey addressing backgrounds, application processes, training experiences,...
BACKGROUND:The natural history of typical pulmonary carcinoid tumors has not been described and important implications for counseling elderly patients or with high operative-risk about surgical resection.METHODS: Data from the Surveillance, Epidemiology, End Results Program were used to identify 4,111 biopsy specimen-proven lymph node-negative tumor lung between 1988 2010; 306 had no resection, 929 underwent sublobar 2,876 lobectomy. Overall survival disease-specific (DSS) analyzed using...