A5001909211- Solar and Space Plasma Dynamics
- Ionosphere and magnetosphere dynamics
- Magnetic confinement fusion research
- Monoclonal and Polyclonal Antibodies Research
- Blood groups and transfusion
- Complement system in diseases
- Stellar, planetary, and galactic studies
- Geomagnetism and Paleomagnetism Studies
- Immunodeficiency and Autoimmune Disorders
- Erythrocyte Function and Pathophysiology
- Glycosylation and Glycoproteins Research
- Fusion materials and technologies
- Cellular Automata and Applications
- Particle accelerators and beam dynamics
- Superconducting Materials and Applications
- Complex Systems and Time Series Analysis
- Statistical Mechanics and Entropy
- Astro and Planetary Science
- Gamma-ray bursts and supernovae
- Theoretical and Computational Physics
- Plasma Diagnostics and Applications
- Hemoglobinopathies and Related Disorders
- Digestive system and related health
- Chaos control and synchronization
- Vitamin K Research Studies
Aristotle University of Thessaloniki
2016-2025
University of Lausanne
1979-2015
Center for Cancer Research
1982-2015
Dana-Farber/Boston Children's Cancer and Blood Disorders Center
2015
Netherlands Institute for Radio Astronomy
2006
University of Patras
1997
ETH Zurich
1991-1994
University of Bern
1949-1986
University of Basel
1975
Swiss Cancer Center Léman
1969
Summary Intravenous administration of standard human γ‐globulin can lead to untoward reactions. This is due at least one endogenous and an exogenous factor. The “endogenous” factor revealed by the finding that certain subjects only ‐ especially patients with antibody deficiency syndrome react intravenous infusions administered under conditions. “exogenous” resides in preparation itself related its anticomplementary activity. be temporarily eliminated “desensitizing” patient; may...
Five differently isolated and purified human C1q preparations were examined by electron microscopy analyzed polyacrylamide gel electrophoresis in 0.1% sodium dodecyl sulfate 0.5 M urea. The amino acid carbohydrate composition of the DNA method are reported compared with results obtained on other procedures. Electron showed that all had six peripheral subunits connected fibrillar strands to a central subunit. presence small amounts dimers was also observed. physico-chemical properties...
Fibronectin immobilized to plastic tubes binds soluble C1q with a Kd of 82 +/- 2.6 nM. The binding fibronectin is relatively insensitive pH but sensitive ionic conditions. covalently bound Sepharose selectively cellular produced by hamster fibroblast cell line. globular head regions have no effect on the collagenous tails interfere competitively Ki 59 We conclude that via its collagen-like tail region and thus process resembles gelatin. This further emphasized our observation gelatin 131...
The purpose of this tutorial is to introduce the main concepts behind normal and anomalous diffusion. Starting from simple, but well known experiments, a series mathematical modeling tools are introduced, relation between them made clear. First, we show how Brownian motion can be understood in terms simple random walk model. Normal diffusion then treated (i) through formalizing model deriving classical equation, (ii) by using Fick's law that leads again same (iii) stochastic differential...
A detailed cross-device investigation on the role of filamentary dynamics in high-density regimes has been performed within EUROfusion framework, comparing ASDEX Upgrade (AUG) and TCV tokamaks. Both devices run density ramp experiments at different levels plasma current, keeping toroidal field or q95 constant order to disentangle parallel connection length current. During scan a field, both scrape-off layer (SOL) profiles tend develop clear SOL shoulder lower edge whenever current is...
The TCV tokamak is augmenting its unique historical capabilities (strong shaping, strong electron heating) with ion heating, additional heating compatible high densities, and variable divertor geometry, in a multifaceted upgrade program designed to broaden operational range without sacrificing fundamental flexibility. rooted three-pronged approach aimed at ITER support, explorations towards DEMO, research. A 1 MW, tangential neutral beam injector (NBI) was recently installed promptly...
Electron and proton acceleration in three-dimensional electric magnetic fields is studied through test particle simulations. The are obtained by a magnetohydrodynamic simulation of reconnection slab geometry. nonlinear evolution the system characterized growth many unstable modes initial current sheet fragmented with formation small scale structures. We inject at random points inside evolving Maxwellian distribution particles. In relatively short time (less than millisecond) particles...
Lipid vesicles containing phospholipids known to be present in substantial amounts mitochondrial membranes were tested for their capacity activate C1. Among them, only cardiolipin (CL) was highly efficient C1 activation; no such effect observed with phosphatidylcholine, phosphatidylethanolamine, or phosphatidylinositol. CL shown bind specifically C1q, because unlabeled C1q competed 125I-C1q binding CL. The requirement confirmed by the finding that fully reconstituted macromolecular C1,...
Aims.To perform numerical experiments of particle acceleration in the complex magnetic and electric field environment stressed solar corona.Methods.The fields are obtained from a 3-D MHD experiment that resembles coronal loop with photospheric regions at both footpoints. Photospheric footpoint motion leads to formation hierarchy stochastic current sheets. Particles (protons electrons) traced within these sheets starting thermal distribution using relativistic test code.Results.In corona...
The concentration of IgG, IgA and IgM has been measured in the cervico-vaginal secretions 8 women with a normal menstrual cycle, 52 pregnant women, 6 post-menopausal 12 total hysterectomy. No significant difference immunoglobulin levels was found cycle as compared to those or women. A decrease IgG/IgA ratio noticed during ovulation consequence increased secretion. In patients hysterectomy, are vaginal origin only contain negligible quantities IgA. Secretory is essentially superior genital...
We analyze statistically the energization of particles in a large scale environment strong turbulence that is fragmented into number distributed current filaments. The turbulent generated through strongly perturbed, 3D, resistive magnetohydrodynamics simulations, and it emerges naturally from nonlinear evolution, without specific reconnection geometry being set up. Based on test-particle we estimate transport coefficients energy space for use classical Fokker-Planck (FP) equation, show...
This Letter presents an analysis of particle acceleration in a model the complex magnetic field environment flaring solar corona. A slender flux tube, initially hydrodynamic equilibrium, is stressed by random photospheric motions. three-dimensional MHD code used to follow stochastic development transient current sheets. These processes generate highly fragmented electric field, through which particles are tracked using relativistic test code. It shown that both ions and electrons accelerated...
With the characterization of an increasing number molecules that are capable activating 1st component classical pathway complement (C), possibility some Gram-negative bacteria may activate C1 independent naturally occurring antibody has been reexamined. We have confirmed a previous report purified (the activated form C1) can bind to certain strains and it retains its enzymatic activity when thus bound. The availability in precursor allowed us extend these observations native molecule. Using...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Christos Tsironis, Arthur G. Peeters, Heinz Isliker, Dafni Strintzi, Ioanna Chatziantonaki, Loukas Vlahos; Electron-cyclotron wave scattering by edge density fluctuations in ITER. Phys. Plasmas 1 November 2009; 16 (11): 112510. https://doi.org/10.1063/1.3264105 Download citation file: Ris (Zotero) Reference...
We review the current literature on formation of coherent structures (CoSs) in strongly turbulent 3D magnetized plasmas. CoSs [Current Sheets (CS), magnetic filaments, large amplitude disturbances, vortices, and shocklets] appear intermittently inside a plasma are collectively locus energy transfer (dissipation) into particle kinetic energy, leading to heating and/or acceleration latter. especially CSs also evolving fragmenting, becoming locally source new clusters CoSs. Strong turbulence...
We study the acceleration of electrons and protons interacting with localized, multiple, small-scale dissipation regions inside an evolving, turbulent active region. The are unstable current sheets (UCSs), in their ensemble they form a complex, fractal, evolving network centers. Acceleration energy thus assumed to be fragmented. A large-scale magnetic topology provides connectivity between UCSs this way determines degree possible multiple acceleration. particles travel along field freely...
We consider a large scale environment of turbulent reconnection that is fragmented into number randomly distributed Unstable Current Sheets (UCS), and we statistically analyze the acceleration particles within this environment. address two important cases mechanisms when interact with UCS: (a) electric field acceleration, (b) through reflection at contracting islands. Electrons ions are accelerated very efficiently, attaining an energy distribution power-law shape index $1-2$, depending on...
Turbulence, magnetic reconnection, and shocks can be present in explosively unstable plasmas, forming a new electromagnetic environment, which we call here turbulent where spontaneous formation of current sheets takes place. We will show that the heating acceleration particles is result synergy stochastic (second order Fermi) systematic (first inside fully developed turbulence. The solar atmosphere magnetically coupled to driver (the convection zone), therefore appearance reconnection...
Solar energetic particles are an integral part of the physical processes related with space weather. We present a review for acceleration mechanisms to explosive phenomena (flares and/or coronal mass ejections, CMEs) inside solar corona. For more than 40 years, main two-dimensional cartoon representing our understanding corona remained almost unchanged. The flares and CMEs also unchanged were same cartoon. In this review, we revise standard evidence from recent global magnetohydrodynamic...